In other hyperuricemic conditions (increased uric acid level in blood) but very rarely
Contraindications of Febuxostat
When should one not use Febuxostat
Do not take it if you have any allergic reactions to Febuxostat.
Side effects of Febuxostat
Common side effects of this drug are:
Nausea, diarrhea, joint pain, headache
Increased liver enzyme levels and rash
Sometimes severe allergic reactions.
Severe skin reaction like blister, shading of skin, rashes (Steven’s Johnson syndrome)
Precautions and Warnings of Febuxostat
Can I take Febuxostat during pregnancy?
No adequate data about the safety of this medicine in pregnancy. Febuxostat should not be used during pregnancy.
Can I take Febuxostat while breastfeeding?
It is unknown whether Febuxostat may pass into human breast milk. Hence it is unsafe to use if you are breastfeeding or if you are planning to breastfeed.
Can I drive if I have consumed Febuxostat?
If during Febuxostat treatment, you feel dizziness, sleepiness or blurred vision, try to avoid driving.
Can I consume alcohol with Febuxostat?
No known interaction with alcohol. Alcohol is known to increase uric acid levels in the body and can worsen the underlying condition of gout. Avoid excessive consumption of alcohol.
Other General Warnings
Talk to your doctor if
You have heart problems
You have renal disease
You have serious allergic reaction to Allopurinol (a medication used for the treatment of Gout)
You have liver disease
You have thyroid problems
While starting treatment with this medicine, you may get gout flare up. However, continue taking medicine
Mode of Action of Febuxostat
How Does It Work?
Gout is associated with increased uric acid levels
Febuxostat blocks an enzyme in the production of this uric acid and lowers its level
Interactions of Febuxostat
Interactions with other medicines
Medicines used to treat cancer (Mercaptopurine)
Medicines used to reduce immune response (Azathioprine)
Medicines used to treat asthma (Theophylline)
Interactions with food items
No information is available on interactions of this when taken with food, consult your doctor or pharmacist for further information.
Dietary Restrictions of Febuxostat
Avoid meat, beef as these can increase uric acid levels. You are advised to maintain a good amount of water intake while on this medicine.
Dosage of Febuxostat
Symptoms of overdose of Febuxostat may include dizziness, nausea, vomiting, rash, headache, etc. Seek emergency medical care immediately.
Missed a Dose
If you missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compensate for a missed one....
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