Estriol

Molecule Description

Estriol is similar to the naturally occurring hormone estrogen. It is used as H

ormone Replacement Therapy (HRT) in women after menopause.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Estriol

Osteoporosis (which cause weakening of bones)
Hormone replacement therapy
Vaginal dryness (topical cream/gel)

Contraindications of Estriol

When should one not use Estriol

Do not take this medicine if:
You are allergic to this medicine
You have breast cancer
You have liver disease
You have clots in blood
You have cancer of the womb lining (endometrial cancer)
You have an extensive thickening of the womb lining (endometrial hyperplasia)
You have any unexplained vaginal bleeding
You have porphyria

Side effects of Estriol

Common side effects of this drug are:

Nausea and vomiting
Breast tenderness
Headache
Vaginal spotting
Pain during urination
Stomach upset
Skin rash
Pain in legs
Difficulty to breath and swallow
Jaundice
Swelling of face or throat
Increase blood pressure

Precautions and Warnings of Estriol

Pregnancy

Can I take Estriol during pregnancy?

It is probably unsafe to use this medicine during pregnancy as it may harm the unborn baby.

Breast Feeding

Can I take Estriol while breastfeeding?

Limited data available for the amount of medicine passing in breast milk during breastfeeding. Therefore avoid this medicine if you are breastfeeding.

Driving

Can I drive if I have consumed Estriol?

Limited data are available about the effect of this medicine on driving.

Alcohol

Can I consume alcohol with Estriol?

No study available about the interaction of this medicine with alcohol.

Other General Warnings

Talk to your doctor if

You have abnormal growth in womb inside or outside
You have high blood pressure, heart disease, liver disease, kidney disease or diabetes
You have gallbladder stone, migraine, headache, seizures or asthma
You have a high triglyceride level and autoimmune disease called Systemic Lupus Erythematosus (SLE)

Mode of Action of Estriol

How Does It Work?

Estriol helps in maintaining the estrogen levels in postmenopausal females.

Interactions of Estriol

Interactions with other medicines

Medicines for epilepsy(like Barbiturates, Lamotrigine, Hydantoins, and Carbamazepine)
Medicines for infections (like Griseofulvin and Rifamycin)
Medicines for viral infections (like Nevirapine, Efavirenz, Ritonavir or Nelfinavir)
Corticosteroids
Theophylline or Succinylcholine

Interactions with food items

No specific interactions with food have been reported yet.

Dietary Restrictions of Estriol

No information is available on dietary restrictions while you are taking this medicine, so consult your doctor or pharmacist for further details.

Dosage of Estriol

Overdose

The effect of an overdose may be harmful and need immediate medical attention. The symptoms of overdose can be nausea, vomiting and headache. If you happen to take an overdose of the medicine, seek em...

Missed a Dose

Take the missed dose of medicine as early as you remember. Skip the missed dose and do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mahesh Muthe

MBBS

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Estriol?

Inform the doctor about your detailed medical, surgical and allergy history
Inform your physician if you have any of the following conditions -
Uterine fibroids, endometriosis
Breast cancer
Blood pressure, stroke
Liver disease
Gallbladder disease
Seizures
Asthma
Inform if you are pregnant, lactating or planning a pregnancy

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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