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Eribulin Mesylate

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Molecule Summary

Uses
Breast cancer
Therapy
Anti-Neoplastic
Side Effects
Hair loss, nausea, constipation, decreased white blood cell count, fatigue, peripheral neuropathy
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Molecule Description

Eribulin Mesylate is used to treat breast cancer. It contains the active substance eribulin, which belongs to the class of antineoplastic agents. Eribulin Mesylate can be administered alone or in combination with certain other medicines as part of combination chemotherapy. It is given as an injection under the supervision of a doctor. Your doctor will determine the necessary dose and how often you need to take it. The most common side effects of this medicine include weakness, hair loss, nausea, and constipation. Before taking it, inform your doctor if you have heart disease, liver or kidney issues, or if you are taking any medications to treat infections. Many other medicines can affect or be affected by this medicine, so make sure to inform your doctor about all medications you are currently using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception for both males and females during treatment is essential to prevent pregnancy.

Uses

Eribulin Mesylate is used to treat breast cancer.

Contraindications

When should one not use Eribulin Mesylate

If you are allergic to Eribulin or any of the other ingredients in Eribulin Mesylate.

Side effects

Common side effects of this drug are:

  • Hair loss
  • Nausea
  • Constipation
  • Decreased white blood cell count
  • Fatigue
  • Peripheral neuropathy

Precautions and Warnings

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience signs or symptoms of peripheral motor and sensory neuropathy (e.g., numbness, tingling, weakness in your arms or legs).
  • You have pre-existing neuropathy greater than Grade 2.
  • You have congestive heart failure.
  • You have bradyarrhythmias (slow heart rate).
  • You are taking other medications known to prolong the QT interval, including Class Ia and III antiarrhythmics.
  • You have electrolyte abnormalities such as hypokalaemia (low potassium), hypocalcaemia (low calcium), or hypomagnesaemia (low magnesium).
  • You have congenital long QT syndrome.

Mode of Action

How Does It Work?

Eribulin is a chemotherapy drug that disrupts cell division by interfering with microtubules, which are essential for cell structure and movement. It inhibits microtubule growth, leading to mitotic spindle dysfunction and, ultimately, cell death.

Dosage

Overdose

Your doctor or nurse will administer this medicine. As a result, the chances of an overdose are very rare. If you experience symptoms shortly after receiving the medicine, seek medical assistance.

Missed a Dose

Your doctor or nurse will monitor and schedule your medicine carefully, making it unlikely that a dose will be missed. However, if you suspect that a dose has been overlooked, let them know immediately.

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