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Doripenem

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Molecule Summary

Uses
Bacterial infection of stomach and urinary tract
Therapy
Antibiotic
Side Effects
Headache, nausea, diarrhoea, rash, inflammation or swelling of a vein
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Molecule Description

Doripenem is an antibiotic medicine that is used to treat severe bacterial infections of the stomach, urinary tract and swelling of the kidney due to a bacterial infection. It belongs to the carbapenem class of antibiotics. Doripenem is not to be used in viral infections like flu, cold, etc. It will be given to you in a hospital or clinic by a doctor or nurse as an injection. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history, before starting this medicine.

Uses

  • Complicated stomach infections
  • Complicated urinary tract infections, including pyelonephritis (a condition of swelling of the kidney due to a bacterial infection)

Contraindications

When should one not use Doripenem

  • If you are allergic to doripenem or any of the other ingredients of Doripenem.
  • If you are allergic to any other antibiotics belonging to the penicillin or cephalosporin class of antibiotics (called beta-lactams).

Side effects

Common side effects of this drug are:

  • Headache
  • Nausea
  • Diarrhoea
  • Rash
  • Inflammation or swelling of a vein

Precautions and Warnings

Pregnancy

Pregnancy

Doripenem should be avoided during pregnancy due to the lack of safety information. Tell your doctor if you are pregnant or think you may be pregnant while he prescribes you this medicine.

Breast Feeding

Breast Feeding

It is not known if Doripenem passes into breast milk. To avoid any harm to the breastfeeding infant, consult the doctor if you are breastfeeding before initiating therapy and he may suggest either discontinuing breastfeeding or treatment.

Driving

Driving

There is no information available on the effect of the medicine on the driving abilities of an individual. If you experience dizziness after the administration of Doripenem, avoid driving.

Alcohol

Alcohol

There is no known interaction between alcohol and Doripenem. However, long term use of alcohol weakens your immune system and body's response to pathogens and infections. Consult the doctor for more information if you drink too often.

Mode of Action

How Does It Work?

Doripenem inhibits the formation of the bacterial protective covering (cell wall), which is needed for bacteria to survive, thereby restricting their growth and eventually killing the bacteria.

Interactions

Interactions with other medicines

  • Some medicines affect the way Doripenem works or Doripenem itself reduces the effectiveness of other medicines taken at the same time.
  • Inform the doctor about medicines, supplements or herbals you are taking or might take to avoid possible interactions.
  • Especially if you are taking any brain-related medicines such as valproic acid and anti-gout medicines like probenecid.

Dosage

Overdose

Doripenem will be given by a doctor or nurse; thus, the chances of an overdose are unlikely. However, if you experience any discomforts or unusual symptoms, inform the doctor or reach out to the nearest hospital.

Missed a Dose

It is unlikely that the dose of the medicine will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the medicine, inform the doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Doripenem is an antibiotic medicine. It is used for the treatment of serious bacterial infections associated with the stomach and urinary tract, including swelling in the kidneys due to bacterial infection.

Doripenem will be given to you by a doctor in a clinic/hospital, avoid self-medicating. The route of administration, dose and duration will be decided by the doctor after careful assessment of the condition you are being treated for and other parameters. Do not self-inject this medicine. Follow the aftercare instruction given by the doctor.

Yes, Doripenem is an antibiotic medicine, that belongs to carbapenem group of antibiotics.

No, the doctor will prescribe you the appropriate medicine on the basis of the medical history and severity of the underlying condition and medical history. If you have been tested positive for covid-19, immediately inform your doctor. Do not take any medicine to treat or prevent covid-19 without consulting a doctor.

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