Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm)
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Molecule Summary
| Uses | Osteoarthritis, Joint and Bone disorders |
| Therapy | Drugs For Osteoarthritis |
| Side Effects | Nausea, vomiting, diarrhoea, headache |
Medicines
available
19k pincodes
Molecule Description
Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) is used in the treatment of osteoarthritis of the knee and hip joint. It is a combination medicine containing methyl sulfonyl methane (MSM), diacerein and glucosamine as the active ingredients. It reduces pain and swelling by reducing inflammation. It also reduces friction in the joints and provides comfort during physical movements. They do so by increasing the cushioning effect between the joints. It should be taken as directed by the doctor and in doses and duration as prescribed. You may experience diarrhoea, headache, nausea and stomach pain after taking Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm). If these symptoms do not resolve or worsen, consult your doctor. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm).
Uses
Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) is used to treat osteoarthritis of the knee and hip joints, especially in the initial stage of the disease.
Contraindications
When should one not use Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm)
If you are allergic to glucosamine, diacerein, methyl sulfonyl methane (MSM) or any other component of Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm).
Side effects
Common side effects of this drug are:
- Nausea
- Vomiting
- Diarrhoea
- Constipation
- Heartburn
- Headache
- Insomnia
- Itching
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of or are suffering from liver, heart or kidney disease.
- If you have any other joint disease/ condition, find out the exact cause.
- You are suffering from diabetes or asthma.
- You are on antibiotics for any other medical condition, as it may increase the risk of stomach problems.
- You are pregnant, think you may be pregnant or are breastfeeding.
- You have experienced diarrhoea due to Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) earlier.
- You have constipation and are on laxative medication for the same.
- Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) is not recommended for use in children below 18 years of age.
Mode of Action
How Does It Work?
- Methyl Sulfonyl Methane (MSM) acts as a nutritional supplement to the bones. It contains sulphur which is vital in the production of collagen and glucosamine, which in turn help in strengthening and repairing the bones and joints. MSM additionally lowers inflammation (swelling) of the joints.
- Diacerein works by blocking the actions of a chemical substance called interleukin-1 beta, which leads to swelling, pain and degradation of cartilage at the joints. It also helps in the built-up of cartilage thereby aiding in joint repair and healing.
- Glucosamine is a chemical substance found in the fluid around the joints (synovial fluid). It helps the synthesis of synovial fluid which keeps the joints lubricated and provides better movement and flexibility. It promotes the build-up of cartilage, thereby helping in joint repair and reduces pain and improves its healing.
Interactions
Interactions with other medicines
- Some medicines can affect the way Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) works or Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) itself can affect the action of other medicines taken at the same time.
- Tell your doctor about all the medicines you are currently taking, recently taken or might take to avoid any possible interactions.
- Particularly, if you are on medicines used to treat diabetes such as tolbutamide, painkillers such as indomethacin, aspirin or medicine used to treat brain-related disorders such as chlorpromazine.
- Use of Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) with blood-thinning medicines like warfarin can increase the risk of bleeding.
Dosage
Overdose
Taking more than the recommended dosage of Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm) can cause profuse diarrhoea. If you have taken too much of this medicine, then contact your doctor or reach out to the nearest hospital immediately.
Missed a Dose
If you have missed taking any dose of Diacerein+Glucosamine Sulphate+Methyl Sulfonyl Methane(Msm), then take it as soon as you remember. If it's already time for the next dose, then skip the missed dose and follow the regular dosing schedule.
Frequently Asked Questions (FAQs)
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References:
- Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017 Mar 16;9(3):290. [cited 4 June 2026].
- Guo S, Guo X, Zhang H, Zhang X, Li Z. The Effect of Diacerein on Type 2 Diabetic Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis. J Diabetes Res. 2020 Feb 10;2020:2593792. [cited 4 June 2026].
- Veronese N, Demurtas J, Smith L, Reginster JY, Bruyère O, Beaudart C, Honvo G, Maggi S; on behalf on the European Geriatric Medicine Society Special Interest Groups in Systematic Reviews and Meta-Analyses and Arthritis. Glucosamine sulphate: an umbrella review of health outcomes. Ther Adv Musculoskelet Dis. 2020 Dec 26;12:1759720X20975927 [cited 4 June 2026].
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