Cinacalcet

• The treatment of high levels of calcium in the blood
• The treatment of high levels of parathyroid hormone in the blood due to parathyroid cancer or primary Hyperparathyroidism
• Treatment of secondary Hyperparathyroidism (HPT) in individuals with End Stage Renal Disease (ESRD) on maintenance dialysis therapy

When should one not use Cinacalcet

• Do not take if you are allergic to Cinacalcet or any ingredient of this medicine
• Do not take if you have low calcium levels in blood

Common side effects of this drug are:

• Nausea and vomiting
• Allergic symptoms - itching, hives, rash, swelling of lips, face, throat, etc.
• Muscle pain, tightness
• Convulsion
• Numbness around the mouth
• Shortness of breath, rapid weight gain

Other General Warnings

• In case you are taking treatment for high levels of parathyroid hormone in blood
• Your calcium levels are not monitored before beginning the treatment with this medicine and during the treatment with this medicine
• You feel any signs of low calcium level
• You have kidney disease, heart disease
• Person with severe kidney disease who are not on dialysis

How Does It Work?

Interactions with other medicines

• This medicine has significant interactions with Atomoxetine, Brexpiprazole, Eliglustat, Tamoxifen, Iloperidone, Thioridazine, Pimozide, Vortioxetine, and Tetrabenazine and minor to moderate interactions with numerous medicines
• A patient may require to adjust the dosage of Cinacalcet if he/she initiates or discontinues the therapy with a strong inhibitor (e.g., Ketoconazole, Itraconazole, Telithromycin, Voriconazole, Ritonavir) or inducer (e.g., Rifampicin) of related enzyme

Interactions with food items

Overdose

• The effects of an overdose may be lethal and needs immediate medical attention
• The symptoms of overdose can be – nausea, vomiting, etc. If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately

Missed a Dose