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Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine

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Molecule Summary

Uses
Irritable bowel syndrome, peptic ulcer disease, gall bladder colic
Therapy
Drugs For Irritable Bowel Syndrome
Side Effects
Drowsiness, dryness of mouth, constipation, dizziness, shaking of arms, hands and legs
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Molecule Description

Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine has a combination of three different drugs. The three components of Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine are Chlordiazepoxide, Clidinium and Dicyclomine. These help in providing relief from abdominal pain, spasms, bloating, diarrhoea or constipation in a condition called irritable bowel syndrome (IBS). Irritable bowel syndrome is a common condition of the gut causing cramps in the abdomen, diarrhoea or constipation, bloating and gas. Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine causes relaxation of the muscles of the gut and provides relief from pains and cramps. It also reduces gastric secretions and helps in reducing pain associated with peptic ulcers. Apart from irritable bowel syndrome, Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine is used to treat other conditions such as anxiety and peptic ulcer disease. The treatment for each of these conditions should be taken as advised by the doctor.

Uses

  • Irritable bowel syndrome
  • Abdominal pain due to intestinal, kidney or gall bladder colic
  • Relief of anxiety associated with spasms and pain
  • Menstrual pain
  • Peptic ulcer disease
  • Alcohol withdrawal symptoms

Contraindications

When should one not use Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine

  • If you have known hypersensitivity to this medicine or any of its ingredients.
  • If you have Glaucoma.
  • If you are taking opioid and opioid derivatives.
  • If you are pregnant or a breastfeeding mother.

Side effects

Common side effects of this drug are:

  • Constipation
  • Shakiness in legs, feet or hands
  • Altered taste
  • Blurry vision
  • Fatigue
  • Confusion, forgetfulness
  • Fast heartbeat
  • Drowsiness
  • Dryness of mouth
  • Rashes
  • Some of the rare and serious side effects are:
  • Hallucination
  • Delirium
  • Signs showing intestinal paralysis
  • Severe hypersensitivity reaction- swelling of the face, tongue, eyes
  • Contact a doctor immediately if you experience any of these side effects.

Precautions and Warnings

Pregnancy

Pregnancy

Studies have shown that there is a risk of certain congenital anomalies if this medicine is taken during pregnancy. If you are pregnant or planning to conceive during the course of the treatment, discuss with your doctor. This medicine is not recommended during pregnancy.

Breast Feeding

Breast Feeding

There may be a little risk to the infant if you are taking this medicine and breastfeeding the child. Data shows that this drug passes through the breast milk to the child and may induce breathing problems. This medicine is not recommended during breastfeeding. Inform your doctor if you are breastfeeding the child.

Driving

Driving

No. Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine may cause drowsiness or dizziness. Therefore, your ability to drive safely may be affected.

Alcohol

Alcohol

Having alcohol while on treatment with Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine raises the risk of side effects such as drowsiness, dizziness and breathing problems.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine should be taken only on the advice of the doctor. You should not drive or consume alcohol while on this medication. You should not stop the medicine on your own. Talk to your doctor before starting this treatment if:
  • You are pregnant, breastfeeding the child, or planning to conceive.
  • You have a history of any liver disease, kidney disease
  • You have any respiratory disease or heart condition.
  • You are on other medications that you are already taking.
  • You are allergic to any of the ingredients.
  • You are taking sleeping pills or anti-anxiety medicines.

Mode of Action

How Does It Work?

The three ingredients in Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine work together to provide relief from painful spasms of the abdomen and the anxiety associated with these conditions. Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine is composed of Chlordiazepoxide, Clidinium, and Dicyclomine. Chlordiazepoxide is a sedative-hypnotic. It acts on excessive activity in the brain and produces a calming effect by binding certain chemicals in the brain. It alleviates anxiety-related recurrent abdominal spasms in irritable bowel syndrome. It is also used to reduce the effects of alcohol withdrawal. Clidinium is an anticholinergic drug and has antispasmodic action. It acts by blocking the secretions of certain chemicals in the smooth muscles, thereby providing relief from abdominal spasms and cramps. It is also used to relieve pain in peptic ulcer disease. Dicyclomine acts by relaxing the muscles in the intestines and slows down the movements of the intestinal tract, thereby bringing relief from muscle pain in the abdomen.

Interactions

Interactions with other medicines

  • Concomitant use with opioids is not recommended as it has a potential risk of respiratory depression, coma and death.
  • Concomitant use with other psychotropic agents (medicines that affect the brain and mood) should be discussed with your doctor.
  • Certain pain-relievers may increase the intensity of the side effects caused by the dicyclomine content of the medicine. These medicines are acetaminophen, acemetacin, aceclofenac, acetylsalicylic acid. You should consult your doctor before taking this medicine.
  • Some medicines increase the risk of side effects caused by Clidinium, such as acetazolamide, acetophenazine, benzodiazepines, atropine, belladonna, baclofen.
  • Sleeping pills or anti-anxiety medicines such as alprazolam may increase drowsiness and should be discussed with your doctor.

Interactions with food items

  • Alcohol consumption should be avoided while on this medication. Alcohol may increase the risk of the side effects related to the medicine, such as drowsiness and dizziness.
  • Avoid caffeine or carbonated drinks.
  • Avoid rich, oily and spicy food.

Dosage

Overdose

The symptoms of overdosage are headache, dry skin, excessive dryness of mouth, blurring of vision, nausea, vomiting, dizziness, difficulty in breathing and swallowing. Reach out to emergency services or your doctor if you experience one or more of these symptoms

Missed a Dose

If you have missed a dose, then take the medicine as soon as you remember it. But if the time to take the next dose is near, then stick to the scheduled dose and do not take the missed dose. You should not take the missed dose and the next dose together.

Frequently Asked Questions (FAQs)

Yes. Chlordiazepoxide, one of the ingredients of Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine, is a sedative-hypnotic. It helps in calming the brain and alleviating anxiety. It should be taken only after consulting the doctor.

Dryness of mouth is one of the side effects of Chlordiazepoxide+Clidinium+Dicycloverine / Dicyclomine. Drinking plenty of water and taking sips of water throughout the day helps keep the mouth moist. You can use lip balm if your lips feel dry.

Avoid smoking and alcohol. Alcohol increases the risk of drowsiness and dizziness when consumed while taking this treatment. Avoid spicy and fried food to reduce the risk of heartburn. Avoid caffeinated and carbonated drinks as they may induce bloating and discomfort.

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