Cefotaxime

Uses	Bacterial infections
Therapy	Antibiotic
Side Effects	Pain at injection site, diarrhoea, rashes, nausea, vomiting

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Molecule Description

Cefotaxime is a cephalosporin antibiotic used to treat bacterial infections of the lungs, airways, skin, and genitals. This medicine should be used under medical supervision and for the duration that it is prescribed. Before using this medicine, inform the doctor about your detailed medical history. Cefotaxime will be given to you by your doctor or nurse. Do not self-inject this medicine.

Uses

Cefotaxime is used for the treatment of bacterial infections of the respiratory tract, urinary tract, skin, stomach, and genitals.

Contraindications

When should one not use Cefotaxime

If you are allergic to cefotaxime or any other ingredient of this medicine.
If you are allergic to beta-lactam antibiotics like penicillin and cephalosporins. If you are not sure what these medicines are, please confirm with your doctor.

Side effects

Common side effects of this drug are:

Pain at the injection site
Rashes
Diarrhoea
Nausea
Vomiting

Precautions and Warnings

Pregnancy

There is limited information on the effect of Cefotaxime during pregnancy. This medicine should be used in pregnancy only if your doctor recommends it.

Breast Feeding

Cefotaxime may pass into human breast milk. This medicine should be used in breastfeeding women only if recommended by the doctor.

Driving

Cefotaxime may cause dizziness and drowsiness. If you experience any such symptoms which may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

There is limited information available regarding the interaction of alcohol with Cefotaxime. Ask your doctor for advice on alcohol intake along with Cefotaxime.

Other General Warnings

Talk to your doctor if

You have or had an allergic reaction to cephalosporins or penicillins.
You experience skin redness or weakness after taking this medicine.
You develop persistent diarrhoea during treatment with this medicine
You have a pre-existing medical condition like liver, kidney, or heart disorder.
You are taking medicines like streptomycin or amikacin along with this medicine.

Mode of Action

How Does It Work?

Cefotaxime binds to certain proteins called penicillin-binding proteins (PBPs) and prevents the formation of the bacterial cell wall. This results in the death of infection-causing bacteria.

Interactions

Interactions with other medicines

Some medicines can affect the way Cefotaxime works, or Cefotaxime itself may reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
Antibiotics for treating bacterial infections (streptomycin) and water pills for treating fluid retention/high blood pressure (furosemide) when taken along with Cefotaxime may affect kidney functioning.
Particular care should be taken if you are taking medicines for treating gout (probenecid) if you already have an existing kidney disorder.

Dosage

Overdose

Cefotaxime will be given to you by a doctor or nurse, and hence, the chances of an overdose are unlikely.

Missed a Dose

If you think your doctor or nurse might have missed a dose of Cefotaxime, then inform them.

Frequently Asked Questions (FAQs)

You are supposed to complete the prescribed dosage of Cefotaxime. If you have skipped the dose or do not complete the course it may cause resistance and decrease the effectiveness of immediate treatment.

Inappropriate use of antibiotics constitutes taking antibiotics when not needed, for wrong diseases, taking inappropriate dosage and not completing the course of antibiotic treatment as prescribed by the doctor.

Antibiotic resistance is a natural process. It occurs when an antibiotic fails to efficiently control the growth or kill a bacteria causing infection. A bacteria resistant to antibiotics continues to multiply in the presence of antibiotics, which would generally kill them. As resistance develops, these antibiotic medicines become gradually less effective – and eventually, they lose their effectiveness entirely. Antibiotic resistance is a consequence of the excessive and inappropriate use of antibiotics and misuse even when not required.

Ask your doctor for advice on the use of Cefotaxime treating fever. This medicine is specific for treating bacterial infections whereas fever can have various underlying causes. Your doctor may recommend this medicine for fever if it is suitable for you.

Cefotaxime is used for the treatment of bacterial infections of the respiratory tract, urinary tract, skin, stomach, and genitals.

Cefotaxime itself is the active substance. It is a cephalosporin antibiotic.