Cabergoline

Molecule Description

Cabergoline is a ‘Dopamine Agonist,’ which is used to treat Parkinson’s disease

(a disease of the brain that causes tremors).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Cabergoline

Treat symptoms of a nerve disorder due to deficiency of Dopamine (Parkinson’s disease) in whom other treatment options were not effective. Cabergoline can be used alone or in combination with other me...

Contraindications of Cabergoline

When should one not use Cabergoline

Allergy to Cabergoline or any components of the medicine, or to other medicines of the similar group called ‘Ergot Alkaloids’
Any disease of the heart valves (long term usage of Cabergoline also can affect the heart valves)
History of stomach, lung or heart disorders

Side effects of Cabergoline

Common side effects of this drug are:

Heart valve and related problems, infection of the lining of the heart (pericarditis) – difficulty in breathing, pounding heartbeat (palpitations), pain in the chest, back and hip region, swelling of ...
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Feeling sick (nausea), accumulation of fluid causing swelling of feet and ankles
Vomiting, digestion problems, stomach pain, irritation of lining of the stomach, constipation, low blood pressure, sleep disturbances, confusion, headache, dizziness, spinning of head, weakness, breat...
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Strong feeling or impulse to do things which you would not do normally – gambling, increased sexual drive, excessive spending, shopping or eating
Severe allergic skin reactions causing rashes, itching, burning, redness, swelling, muscle spasms (hard and painful), fatigue, psychiatric disorders (uncommon)

Precautions and Warnings of Cabergoline

Pregnancy

Can I take Cabergoline during pregnancy?

Parkinson’s disease is unlikely to affect women of reproductive age. However, data suggests Cabergoline has the potential to harm the unborn baby and must be used in pregnant women only if alternatives do not exist. It is also advised to use birth control methods to avoid getting pregnant while using Cabergoline.

Breast Feeding

Can I take Cabergoline while breastfeeding?

It is unknown if Cabergoline secretes in breast milk, but the production of breast milk in the mother can be affected by this medicine. It is recommended to avoid Cabergoline while breastfeeding.

Driving

Can I drive if I have consumed Cabergoline?

Cabergoline is used to treat a disorder that causes a lack of coordination in movements. It also causes side effects such as drowsiness, feeling sleepy, or decreased alertness. Hence caution is advised if you have to drive while taking this medicine and avoid driving in the presence of side effects.

Alcohol

Can I consume alcohol with Cabergoline?

In disorders of the brain, alcohol is not safe because it depresses brain activity and can increase the side effects. If you are taking Cabergoline, limit your consumption of alcohol.

Other General Warnings

Talk to your doctor if

Heart, lung or liver problems
Reduced blood supply to hands and feet in cold conditions (Raynaud's disease)
Ulcers or bleeding of the stomach and intestines
Psychiatric disorders
Growth of scar tissue (fibrosis) in the heart, lungs or the stomach
Regular monitoring of heart, lungs, kidneys, and blood is required, especially if long-term treatment with Cabergoline is planned

Mode of Action of Cabergoline

How Does It Work?

Dopamine is a substance secreted in the brain that transmits signals (neurotransmitters), whose primary function is to regulate movements. Cabergoline acts by increasing Dopamine levels in the brain a...

Interactions of Cabergoline

Interactions with other medicines

Cabergoline may interact with medicines used to treat migraine (Ergot medicines), sickness or vomiting (Metoclopramide), mental illness (Prochlorperazine, Chlorpromazine, Haloperidol, Chlorprothixene)
Antibiotics (Erythromycin, Clarithromycin)

Interactions with food items

You are advised to take Cabergoline with food and a glass of water.

Dosage of Cabergoline

Overdose

Unintentional overdose with Cabergoline may not be harmful. But if you experience any side effects such as stomach pain, low blood pressure, vomiting, or any behavioral changes, consult your doctor.

Missed a Dose

Take the missed dose as promptly as you remember. Skip the missed dose if it is too late, but do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Q: What is Parkinson’s disease, and how can this affect me?

A: Parkinson’s disease is caused due to age-related death of nerve cells in the brain that secrete Dopamine. Decreased levels of Dopamine in the brain will cause problems with movement, loss of coordinated actions, and loss of control over some functions. Unintentional tremors, slow movement, loss of balance, and stiffness are the main symptoms. Parkinson’s disease may not be curable. Still, the symptoms can be controlled, and the patient can lead an ordinary life if he or she takes medicines regularly and exercises caution and is monitored effectively.

Q: What else should I know before starting Cabergoline?

A: Cabergoline can lower your blood pressure (especially when you suddenly stand up or sit down), most commonly in the first few days. You need not stop the treatment, but consulting your doctor is necessary. Long-term therapy with Cabergoline can cause side effects and should be monitored carefully. Regular testing of the functions of your heart, lungs, kidneys, and blood are required. Cabergoline can cause specific behavioral side effects such as urge or impulse to gamble, spend money, eat, increased sexual drive, etc. (impulse control disorders). If you experience such side effects, inform your doctor promptly, as he/ she may stop your treatment.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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