Bupropion
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Molecule Summary
| Uses | Treatment of smoking addiction and depression |
| Therapy | Deaddiction, Anti-Depressant |
| Side Effects | Sweating, insomnia or difficulty in sleeping, allergic reaction, dryness in the mouth, headache, abdominal pain, nausea, vomiting, taste change, fever, constipation |
Medicines
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Molecule Description
Bupropion is an antidepressant and anti-smoking medication. The medication works by improving some active messengers in the brain that ease the nerves and relax the mind. It is possible to consume Bupropion with or without meals around the same time every day.
Insomnia or difficulty sleeping, poor concentration, sweating, allergic response, headache, vomiting, and dry mouth are all typical adverse effects of this medication. Bupropion can make you unsteady and sleepy, so don't drive or do anything else that demands mental attention while taking Bupropion. Furthermore, most harmful effects are quick and usually subside with time. If these concerns you or do not go away completely, immediately notify your physician.
Uses
- As per CDSCO, Bupropion treats smoking addiction and depression.
Contraindications
When should one not use Bupropion
- If you feel allergic to any active components of Bupropion.
- If you are using Monoamine oxidase inhibitors or MAOI 14 days before Bupropion intake.
- If you possess eating disorders such as Anorexia nervosa or Bulimia.
- If you have a seizure disorder or a history of seizures.
Side effects
Common side effects of this drug are:
- Sweating
- Insomnia or difficulty in sleeping
- Allergic reaction
- Dryness in mouth
- Headache
- Abdominal pain
- Nausea
- Vomiting
- Taste change
- Fever
- Constipation
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You realise dramatic mood, behaviour modifications.
- You have suicidal ideation.
- You have a history of seizures, an eating disorder, or if you consume alcohol.
- You shall take Bupropion first thing in the morning to minimise sleeping problems later that night.
Mode of Action
How Does It Work?
Bupropion helps treat depression by raising the number of chemical signals in the brain that assist in mood regulation. However, the molecular mechanisms underlying its use in the treatment of smoking addiction are unknown.
Interactions
Interactions with other medicines
- Bupropion might interact with the following medications and cause severe adverse effects, including constipation, insomnia or vomiting. The medications are
- Xanthines or asthma medicines like Theophylline.
- Antidepressants such as Phenelzine, Desipramine, Isocarboxazid, Selegiline, Citalopram, Escitalopram, Imipramine, Paroxetine.
- Atypical antipsychotics include Risperidone, Thioridazine.
- Beta-blockers like Metoprolol.
- Antiarrhythmics or heart problems medicines such as Flecainide, Propafenone.
- Protease inhibitors include Ritonavir, Efavirenz.
Interactions with food items
- There is no severe interaction between Bupropion and food. However, you should avoid the junk, packaged or processed foods, grapefruit and caffeine while consuming Bupropion.
Dosage
Overdose
Seek medical help if you take too much Bupropion. If the sufferer has passed out, had a seizure, has problems breathing, or cannot be roused, go to a local hospital. Overdosing on Bupropion can result in hallucinations, seizures, loss of consciousness, and a racing or pounding pulse.
Missed a Dose
Follow your usual dosage plan and ignore the delayed dose. Allow enough time among doses of Bupropion to allow the body to adjust. To compensate for an overdue dosage, do not consume a double amount.
Frequently Asked Questions (FAQs)
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