Buprenorphine
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Molecule Summary
| Uses | Severe pain, Opioid de-addiction |
| Therapy | Analgesic For Severe Pain |
| Side Effects | Headache, constipation, stomach pain, excessive sweating, sleep disturbances. |
Medicines
available
19k pincodes
Molecule Description
Buprenorphine is a strong painkiller used to treat severe pain in adults. Buprenorphine belongs to a class of opioid medicine that reduces severe pain by changing the normal response of the brain and nervous system towards pain.
Uses
- Severe pain
- De-addiction therapy for those addicted to narcotics
Contraindications
When should one not use Buprenorphine
If you're allergic to buprenorphine or any other ingredients present in the medicine
Side effects
Common side effects of this drug are:
- Stomach pain
- Constipation
- Headache
- Sleep disturbances
- Blurred vision
- Excessive sweating
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You are taking medications before starting Buprenorphine.
- You have severe breathing problems.
- You have suffered any head injury or brain disorders.
- You have liver or kidney problems.
- You suffer from pancreas disease.
Mode of Action
How Does It Work?
Buprenorphine reduces pain by changing the normal response of the brain and nervous system towards pain. It also prevents the withdrawal symptoms in patients undergoing de-addiction from opioids by producing similar effects as an opioid.
Interactions
Interactions with other medicines
- Buprenorphine may adversely interact with medicines to treat depression, such as paroxetine, to cause fits and seizures and may even lead to coma (as the brain activity is suppressed significantly).
- Buprenorphine may cause breathing difficulties, increased sleepiness, and even coma when taken along with medicines to treat pain (morphine), medicines to treat cough (codeine) and medicines for allergy.
- Buprenorphine becomes less effective when taken with medicines to treat tuberculosis like rifampicin.
Interactions with food items
- Buprenorphine may interact adversely with:
- St. John's Wort (herbal medicine for depression)
- Tryptophan containing dietary supplements (milk, cheese, oats, chicken, tuna fish and nuts)
Dosage
Overdose
- Symptoms of an overdose of Buprenorphine can be fatal and include increased sleepiness, difficulty breathing, blurred vision, dizziness, and even coma. If you happen to take too much of Buprenorphine, reach out to your doctor or the nearest hospital immediately.
Missed a Dose
Buprenorphine must be taken as prescribed by your doctor. If you miss a dose, take it just when you remember it. However, you should skip a missed dose when enough time has passed, and it is time for your next dose. Do not take a double dose of Buprenorphine to make up for the missed dose. This may lead to overdosing.
Frequently Asked Questions (FAQs)
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