Brimonidine Tartrate+Brinzolamide

Uses	Glaucoma
Therapy	Glaucoma Drugs
Side Effects	Irritation or burning in eyes, altered taste sensation, tears from eyes, unsteadiness, headache

3 Step Quality
Assurance

Cash on delivery
available

NPPA
Regulated

Molecule Description

Brimonidine Tartrate+Brinzolamide eye drops contain two medications, brinzolamide and brimonidine. These medications work together to reduce high eye pressure, which helps alleviate symptoms such as eye discomfort and headaches. If left untreated, high eye pressure can cause vision problems. Brimonidine Tartrate+Brinzolamide eye drops should only be used in the affected eye as per your physician's instructions. Before using the eye drops, wash your hands. Always read the label for usage directions. It is important to complete the entire treatment course and take all doses, even if you start to feel better. Burning, irritation, and eye discomfort are common side effects of this medicine. If you experience bothersome side effects or if your condition does not improve, please consult your doctor.

Uses

For the treatment of increased pressure of eyes (open-angle glaucoma and ocular hypertension).

Contraindications

When should one not use Brimonidine Tartrate+Brinzolamide

If you are allergic to Brinzolamide, Brimonidine or any other ingredient of this eye drop.
If you are allergic to sulphonamide medicines.
If you are taking some medicines for mental health disorders (MAO inhibitors, tricyclic antidepressants).
If you are suffering from severe kidney disorder.
If you are suffering from increased acid levels in the blood (hyperchloremic acidosis).
For children below 2 years of age.

Side effects

Common side effects of this drug are:

Irritation or burning in eyes
Altered taste sensation
Tears from eyes
Unsteadiness
Discomfort in eyes
Headache

Precautions and Warnings

Pregnancy

Limited information is available about the safety of Brimonidine Tartrate+Brinzolamide eye drops in pregnancy. Use this medicine only when indicated and prescribed by your doctor.

Breast Feeding

It is not known whether this medicine passes in breastmilk or not. Consult your doctor whether you should continue to breastfeed while you are using Brimonidine Tartrate+Brinzolamide eye drops.

Driving

This medicine usually does not impact your driving ability. You may drive if you feel alert and comfortable.

Alcohol

It is not advised to consume alcohol while using Brimonidine Tartrate+Brinzolamide eye drops as it may lead to worsening of certain side effects.

Other General Warnings

Talk to your doctor if

You wear contact lenses, remove your lenses before instilling the eyedrop and wear it after 15-20 minutes.
You suffer from low blood pressure.
You suffer from raised eye pressure due to angle-closure type.
You have a serious disorder of liver, kidney or heart.
You have a problem with blood circulation (Raynaud's phenomenon, cerebral or coronary insufficiency, thromboangiitis obliterans).
You have a thin lining of eyes.

Mode of Action

How Does It Work?

The pressure inside eyes is raised due to either excessive secretion of fluid (aqueous humour) or reduced outflow of the fluid.
Brimonidine Tartrate+Brinzolamide eye drops contain a combination of two medicines, Brinzolamide and Brimonidine which work together to reduce the secretion of aqueous humour in the eye and increase its outflow from eyes which in turn reduces the pressure of eyes (intraocular pressure IOP).

Interactions

Interactions with other medicines

Concomitant use of oral medicines of the same group or blood pressure-lowering medicines should be done with caution.
Medicines containing salicylate may cause acid-base imbalance when given together with this medicine.
Side effects may worsen if medicines acting on the central nervous system like anaesthetic agents, opiates, barbiturates or sedatives are given concomitantly.
Medicines given for mental health disorders (MAO inhibitors, antidepressants) should be used with caution.
Discuss with your doctor about any other medicines, herbal preparations and supplements you are taking currently to avoid any interactions.

Dosage

Overdose

In case you happen to instil more than the prescribed dose of this medicine, immediately rinse your eyes with clean water. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed instilling this eyedrop, instil it as soon as possible. Do not over-apply the medicine to compensate for the missed application.

Frequently Asked Questions (FAQs)

Do not use this medicine while you are wearing contact lenses. If your doctor has allowed you to use lenses, remove contact lenses before instillation of Brimonidine Tartrate+Brinzolamide eye drops and wait at least 15 minutes or more before reinsertion. A component of this eye drop (Benzalkonium chloride) is known to discolour soft contact lenses.

No, Brimonidine Tartrate+Brinzolamide eye drops is meant to be used as an eye drop. Do not use it for ears. Consult your doctor for the problem in your ears.

If you have been prescribed multiple eye drops or ointments, make sure you give a gap of 15 to 20 minutes between the application of each.