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Balsalazide

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Molecule Description

Balsalazide is a form of another medicine called mesalamine. It is available in inactive form and can be activated by the colonic bacteria into its medicine form.

Uses

Swelling of colon (Inflammation) Long-standing sores and swelling in intestine (Ulcerative colitis)

Contraindications

When should one not use Balsalazide

  • Liver disorder
  • Kidney diseases
  • Any allergic reaction with Salicylate medicines or anti-inflammatory medicines
  • And in those who have suffered from allergic reactions earlier with Aspirin or any other pain reliever medicines

Side effects

Common side effects of this drug are:

  • Headache
  • Nausea
  • Vomiting
  • Joint pain 
  • Diarrhea
  • Abdominal pain 
  • Fever
  • Sore throat
  • Sleeping problems or sleeplessness
  • Poor appetite

Precautions and Warnings

Pregnancy

Pregnancy

This medicine can be used during pregnancy only if advised by a physician.

Breast Feeding

Breast Feeding

It is probably unsafe to use this medicine during breastfeeding due to lack of evidence.

Driving

Driving

Usually, it does not affect your ability to drive.

Alcohol

Alcohol

No study found about interactions with alcohol.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have asthma, any blood disorders, kidney disorder, a confirmed liver disease, an active ulcer
  • You should inform your doctor regarding all the products you use (including prescription medicines, non-prescription medicines and herbal products)
  • Children shouldn't consume this medicine

Mode of Action

How Does It Work?

This medicine works by reducing the production of selective chemicals (prostaglandins) that cause swelling in the intestines.

Interactions

Interactions with other medicines

  • It is advised to avoid the intake of Balsalazide along with Salicylate medicines like Aspirin, NSAIDs like Ibuprofen, etc.
  • Drugs for diabetes (e.g., Repaglinide), Sulfonylureas (e.g., Glipizide), convulsions like Valproic Acid are contraindicated because Balsalazide may increase the risk of the medicine's side effects
  • Drugs for increased blood pressure like Angiotensin-converting enzyme inhibitors like Enalapril, for gouty arthritis like Probenecid or Sulfinpyrazone, should not be taken along with Balsalazide because Balsalazide can decrease their therapeutic activity

Interactions with food items

There has not been a report on the interaction of Balsalazide with food. Consult the doctor in case of any food interactions.

Dietary Restrictions

No information is available on dietary restrictions while you are on a medication of Balsalazide, consult your doctor or pharmacist for further details.

Dosage

Overdose

There is not much information about the symptoms of Balsalazide overdose. Seek immediate medical attention if you took an overdose of this medicine.

Missed a Dose

If you missed any dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose, and take the next dose at the scheduled time. Do not take extra medicine just because you missed the last dose.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations, and nutritional supplements that you may be taking before you start this medication. Tell your doctor if you have allergy with any substance, food or medicine. Inform the doctor if you have any kidney issues or stomach problems like stenosis.

It can be swallowed whole with or without food. The contents of the capsule can be emptied and consumed immediately. You can also chew Balsalazide medicine. Color variation of inner materials may occur if you empty out the contents of the tablet.

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