Aztreonam

Uses	Bacterial infections
Therapy	Antibiotic
Side Effects	Headache, dizziness, rashes, weakness

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Molecule Description

Aztreonam is an antibiotic medication. Aztreonam is used for the treatment of bacterial infections of the urinary tract, lower respiratory tract, skin, soft tissue, bone, joint, intra-abdomen, presence of bacteria in the blood, septicemia, gynaecological infections, and gonorrhoea. This medicine works by killing the infection-causing bacteria. Aztreonam will be given to you by your doctor or nurse. Do not self-inject it. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.

Uses

Aztreonam is used for the treatment of bacterial infections of the:
urinary tract
lower respiratory tract
skin
soft tissue
bone, joint
intra-abdomen
presence of bacteria in the blood
septicemia
gynaecological infections
gonorrhoea

Contraindications

When should one not use Aztreonam

If you are allergic to aztreonam or L-arginine or to any of the other ingredients of this medicine.
If you are pregnant or planning to become pregnant.

Side effects

Common side effects of this drug are:

Headache
Dizziness
Rashes
Weakness

Precautions and Warnings

Pregnancy

Aztreonam is contraindicated for use during pregnancy.

Breast Feeding

Aztreonam passes into human breast milk. This medicine should not be used in breastfeeding women.

Driving

Aztreonam may have an effect on driving ability. If you experience any effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

There is limited information available on the interaction of alcohol with Aztreonam. Ask your doctor for advice on alcohol intake along with this medicine.

Other General Warnings

Talk to your doctor if

You have had an allergic reaction to any antibiotics in the past.
You have diarrhoea or usually get diarrhoea when you take antibiotics.
You have had problems with your stomach or intestines.
You develop severe or prolonged or bloody diarrhoea during or after using Aztreonam.
You have liver or kidney problems.
You are taking medicines to prevent blood clots (anticoagulants).
You have any blood disorders like low blood cells count.
You have skin disorders like blistering of the skin.
You get a positive result in a Coombs test.
You experience fits/seizures.
You are taking any other antibiotic.
You experience symptoms of encephalopathy like unexplained confusion, altered mental function, seizure, or weakness.

Mode of Action

How Does It Work?

Aztreonam works by preventing the formation of the bacterial cell wall which kills the infection-causing bacteria.

Interactions

Interactions with other medicines

Some medicines can affect the way Aztreonam works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
The levels of Aztreonam in the body can be raised when taken along with medicines like probenecid (used for treating gout) and furosemide (used for the treatment of fluid accumulation).
Particular care should be taken if you are taking medicines used to thin the blood.

Dosage

Overdose

The symptoms of an overdose of Aztreonam are confusion, movement disorders, and fainting. However, since this medicine will be given to you by a doctor or nurse, the chances of an overdose are unlikely.

Missed a Dose

It is unlikely that a dose of Aztreonam will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the medicine, inform the doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Aztreonam is used for the treatment of bacterial infections of the: • urinary tract, • lower respiratory tract, • skin, • soft tissue, • bone, joint, • intra-abdomen, • presence of bacteria in the blood, • septicemia, • gynaecological infections, and • gonorrhoea.

Aztreonam will be given in the hospital by your doctor or nurse. Do not self-inject this medicine. Follow any aftercare instructions given by the doctor or nurse.