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Atracurium

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Molecule Summary

Uses
Muscle relaxation
Therapy
Muscle Relaxant
Side Effects
Rashes, itching, redness of skin, wheezing
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Molecule Description

Atracurium is a muscle relaxant. Atracurium is used to relax muscles and to help in the insertion of a breathing tube and with artificial breathing during surgery. It is also used to help patients in intensive care (ICU) with artificial breathing. Atracurium will be given to you by your doctor or nurse. Do not self-inject it. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.

Uses

  • Atracurium is used to relax muscles and to help in the insertion of a breathing tube and with artificial breathing during surgery.
  • It is also used to help patients in intensive care (ICU) with artificial breathing.

Contraindications

When should one not use Atracurium

If you are allergic to atracurium or to any of the other ingredients of Atracurium.

Side effects

Common side effects of this drug are:

  • Rashes
  • Itching
  • Redness of skin
  • Wheezing

Precautions and Warnings

Pregnancy

Pregnancy

The use of Atracurium should be avoided in the first three months of pregnancy and it should not be used during the last six months of pregnancy unless recommended by your doctor.

Breast Feeding

Breast Feeding

Atracurium should only be used in breastfeeding women if recommended by your doctor.

Driving

Driving

No, you should not drive within 24 hours of receiving Atracurium.

Alcohol

Alcohol

There is limited information available on the interaction of alcohol with Atracurium. Ask your doctor for advice on alcohol intake along with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are pregnant or breastfeeding.
  • You had allergic reactions to other muscle relaxants (e.g. curares) in the past.
  • You have heart or blood circulation problems.
  • You have lung disorders or a history of allergy or asthma.
  • You suffer from conditions like myasthenia gravis, Eaton-Lambert syndrome or other neuromuscular diseases.
  • You have severe electrolyte imbalances (unusual levels of ions such as sodium, potassium or chloride in your blood).
  • You are suffering from burns.

Mode of Action

How Does It Work?

Atracurium works by opposing the action of the chemical acetylcholine, which is responsible for muscle contraction. Thus, this opposing effect produces muscle relaxation.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Atracurium works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Particular care should be taken if you are taking antibiotics like aminoglycosides, polymyxins, spectinomycin, tetracyclines, lincomycin, clindamycin and vancomycin (used for treating bacterial infections), antiarrhythmic medicines like lidocaine, procainamide, quinidine (used to control abnormal/irregular rhythm of the heart), diuretics like furosemide, thiazides, acetazolamide, mannitol (used to reduce fluid accumulation), medicines used to control blood pressure or heart-related chest pain or other heart problems (like propranolol, oxprenolol, diltiazem, nicardipine, nifedipine, trimethaphan, hexamethonium and verapamil), antiepileptic medicines like carbamazepine, phenytoin (used for the treatment of fits/seizures), medicines used to treat rheumatism (chloroquine, d-penicillamine), corticosteroids (used to treat allergic emergencies, severe asthma and septic shock), inhalation anaesthetics like isoflurane, desflurane, sevoflurane (medicines to put you to sleep), dantrolene and ketamine (used in anaesthesia), magnesium sulphate (used to treat seizure and a complication of pregnancy called pre-eclampsia in pregnant women and some heart problems), lithium (used to treat mental disorders), quinine (used to treat malaria and leg cramps) and chlorpromazine (used to treat some psychiatric disorders and nausea).

Dosage

Overdose

The symptoms of an overdose of Atracurium are muscle paralysis for a long duration. However, since this medicine will be given to you by a doctor or nurse, the chances of an overdose are unlikely.

Missed a Dose

It is unlikely that a dose of Atracurium will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the medicine, inform the doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Atracurium is used to relax muscles and to help in the insertion of a breathing tube and with artificial breathing during surgery. It is also used to help patients in intensive care (ICU) with artificial breathing.

Atracurium will be given in the hospital by your doctor or nurse. Do not self-inject this medicine. Follow any aftercare instructions given by the doctor or nurse.

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