Atracurium
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Molecule Summary
| Uses | Muscle relaxation |
| Therapy | Muscle Relaxant |
| Side Effects | Rashes, itching, redness of skin, wheezing |
Medicines
available
19k pincodes
Molecule Description
Atracurium is a muscle relaxant. Atracurium is used to relax muscles and to help in the insertion of a breathing tube and with artificial breathing during surgery. It is also used to help patients in intensive care (ICU) with artificial breathing. Atracurium will be given to you by your doctor or nurse. Do not self-inject it. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.
Uses
- Atracurium is used to relax muscles and to help in the insertion of a breathing tube and with artificial breathing during surgery.
- It is also used to help patients in intensive care (ICU) with artificial breathing.
Contraindications
When should one not use Atracurium
If you are allergic to atracurium or to any of the other ingredients of Atracurium.
Side effects
Common side effects of this drug are:
- Rashes
- Itching
- Redness of skin
- Wheezing
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You are pregnant or breastfeeding.
- You had allergic reactions to other muscle relaxants (e.g. curares) in the past.
- You have heart or blood circulation problems.
- You have lung disorders or a history of allergy or asthma.
- You suffer from conditions like myasthenia gravis, Eaton-Lambert syndrome or other neuromuscular diseases.
- You have severe electrolyte imbalances (unusual levels of ions such as sodium, potassium or chloride in your blood).
- You are suffering from burns.
Mode of Action
How Does It Work?
Atracurium works by opposing the action of the chemical acetylcholine, which is responsible for muscle contraction. Thus, this opposing effect produces muscle relaxation.
Interactions
Interactions with other medicines
- Some medicines can affect the way Atracurium works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Particular care should be taken if you are taking antibiotics like aminoglycosides, polymyxins, spectinomycin, tetracyclines, lincomycin, clindamycin and vancomycin (used for treating bacterial infections), antiarrhythmic medicines like lidocaine, procainamide, quinidine (used to control abnormal/irregular rhythm of the heart), diuretics like furosemide, thiazides, acetazolamide, mannitol (used to reduce fluid accumulation), medicines used to control blood pressure or heart-related chest pain or other heart problems (like propranolol, oxprenolol, diltiazem, nicardipine, nifedipine, trimethaphan, hexamethonium and verapamil), antiepileptic medicines like carbamazepine, phenytoin (used for the treatment of fits/seizures), medicines used to treat rheumatism (chloroquine, d-penicillamine), corticosteroids (used to treat allergic emergencies, severe asthma and septic shock), inhalation anaesthetics like isoflurane, desflurane, sevoflurane (medicines to put you to sleep), dantrolene and ketamine (used in anaesthesia), magnesium sulphate (used to treat seizure and a complication of pregnancy called pre-eclampsia in pregnant women and some heart problems), lithium (used to treat mental disorders), quinine (used to treat malaria and leg cramps) and chlorpromazine (used to treat some psychiatric disorders and nausea).
Dosage
Overdose
The symptoms of an overdose of Atracurium are muscle paralysis for a long duration. However, since this medicine will be given to you by a doctor or nurse, the chances of an overdose are unlikely.
Missed a Dose
It is unlikely that a dose of Atracurium will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the medicine, inform the doctor or nurse immediately.
Frequently Asked Questions (FAQs)
Articles
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References:
- Atracurium Besilate 10 mg/ml Solution for Injection - vial - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 10 Jun 2026]
- Atracurium Besilate 10 mg/ml Solution for Injection - vial - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 10 Jun 2026]
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