Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen
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Molecule Summary
| Uses | Pain relief |
| Therapy | Analgesic/Antipyretic, Muscle Relaxant |
| Side Effects | Dizziness, vomiting, diarrhoea, stomach pain |
Assurance
available
Regulated
Molecule Description
Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen is a painkiller and fever-reducing medicine. It is used to relieve pain associated with arthritis, headaches, colds, muscle cramps, menstrual pain, tooth pain, etc. It is a combination medicine containing aceclofenac, paracetamol, and thiocolchicoside as active substances.
Uses
- Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen is used for the treatment of pain and inflammation associated with osteoarthritis and rheumatoid arthritis.
- Headache, toothache, colds, influenza, and menstrual cramps.
- Painful muscle contractions.
Contraindications
When should one not use Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen
- If you are allergic to aceclofenac, paracetamol, thiocolchicoside, or any of the ingredients of Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen.
- If you are taking any other product that contains paracetamol.
- If you have a history of peptic ulcers or any blood disorder.
- If you are pregnant or breastfeeding.
Side effects
Common side effects of this drug are:
- Dizziness
- Vomiting
- Diarrhoea
- Stomach pain
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a severe liver or kidney disease
- You are suffering from bleeding in the stomach or peptic ulcers
- You are alcoholic or are suffering from chronic malnutrition
- You are an elderly person
- You have respiratory disorders like asthma
- You experience severe allergic reactions
- You may develop the liver disease due to prolonged use of Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen
Mode of Action
How Does It Work?
Prostaglandins are chemical substances that cause pain, swelling, and fever. Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen blocks the production of these prostaglandins, thus temporarily controlling fever or pain. It acts on the area of the brain which is responsible for controlling temperature. Thus, it controls the fever.
Interactions
Interactions with other medicines
- Some medicines can affect the way Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Medicines used to treat nausea or vomiting like metoclopramide or domperidone when used concomitantly can alter the effect of this medicine.
- The effect of blood pressure reducing medicines like captopril, enalapril, antidepressants like lithium, and medicines used to treat gout like probenecid can be altered when used concomitantly with this medicine.
- The effect of medicines to treat heart conditions like digoxin and HIV medicines like zidovudine is decreased when used along with this medicine.
- Water pills like furosemide, when used together with this medicine, can result in reduced potassium levels in the blood.
- The effect of blood thinners like warfarin can be enhanced when used together with this medicine.
Interactions with food items
It is advisable to take Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen with food or milk to minimize the risk of gastrointestinal discomfort.
Dosage
Overdose
Symptoms of overdose of Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen may include nausea, vomiting, loss of appetite, excitation, ringing in the ears, drowsiness, dizziness, and stomach ache. If you think you have taken too much Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you missed any dose of Aceclofenac+Thiocolchicoside+Paracetamol / Acetaminophen, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Paracetamol Tablets 500mg (POM) Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 12 June 2026]
- Thiocolchicoside - Drugs.com [Internet]. Drugs.com. 2022 [cited 12 June 2026]
- Aceclofenac 100 mg film-coated Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 12 June 2026]
- Paracetamol Tablets 500mg (POM) - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 12 June 2026]
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 9915886, Thiocolchicoside. Retrieved January 21, 2025
- Carta M, Murru L, Botta P, Talani G, Sechi GP, De Riu PL, Sanna E, Biggio G. The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. ScienceDirect. Accessed on: 21 January 2025.
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