Pantoprazole+Cinitapride
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Molecule Summary
| Uses | Gastro-oesophageal reflux disease (GERD) & functional indigestion |
| Therapy | Antacid And Anti-Reflux |
| Side Effects | Drowsiness, diarrhoea, slow movements, stomach polyps |
Assurance
available
Regulated
Molecule Description
Pantoprazole+Cinitapride is a combination medicine used to treat gastro-oesophageal reflux disease (GERD) & other conditions such as indigestion, acidity. It contains pantoprazole and cinitapride as main components. Gasteroesophageal reflux disease or GERD is a condition where acid from the stomach comes up to the food pipe. This backflow of acid irritates the lining of the food pipe and leads to chest pain and heartburn. Pantoprazole+Cinitapride should be taken as directed by the doctor and in doses and duration as prescribed. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.
Uses
Pantoprazole+Cinitapride is used for the treatment of gastro-oesophageal reflux disease (GERD) & functional indigestion.
Contraindications
When should one not use Pantoprazole+Cinitapride
- If you are allergic to pantoprazole, cinitapride, or any other ingredient in Pantoprazole+Cinitapride
- If you are allergic to other proton pump inhibitor medicines such as pantoprazole, omeprazole, rabeprazole, etc.
- If you have bleeding in the stomach or intestine (gastrointestinal bleeding).
- If you are suffering from holes in the walls of the stomach and intestine (gastrointestinal perforation)
- If you are suffering from complete or partial blockage in the intestine
- If you have a condition of involuntary muscle movements due to some psychiatric medicines.
Side effects
Common side effects of this drug are:
- Drowsiness
- Diarrhoea
- Slow movements
- Stomach polyps (abnormal tissue growths within the inner lining of the stomach)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any liver-related problems
- You have a vitamin B12 deficiency
- You are taking any anti-HIV medicines such as atazanavir or painkillers like aspirin
- You are suffering from perforation in the digestive tract
- You have weak bones, or you are prone to fractures or have bone disorders like weak & brittle bones (osteoporosis)
- You are taking the medicine for the long duration (over a year)
- You are supposed to take a blood test (Chromogranin A)
- You are pregnant or breast-feeding
- You are suffering from stomach or intestinal bleeding
- You have a stomach ulcer or a bleeding disorder
- You are suffering from intestinal blockage
- You are suffering from low magnesium levels
- You had developed an allergic reaction after taking a similar medicine
- You have an underlying medical condition and are taking medicines for any disorder
- Prolonged treatment may lead to involuntary muscle movement in elderly patients
- Use with caution in elderly patients as the risk of side-effects is high
- Pantoprazole+Cinitapride is not recommended to be used in children due to limited safety data
Mode of Action
How Does It Work?
- Pantoprazole+Cinitapride works by the combined action of both its components - pantoprazole and cinitapride.
- Pantoprazole works by inhibiting a pump called the proton pump in the stomach wall, responsible for the secretion of stomach acids for digestion and hence leads to reduced acid production.
- Cinitapride works by increasing the movement in the stomach and intestines, thus accelerates emptying of the stomach. It also eases bowel movements by increasing the coordination between the stomach and intestine.
Interactions
Interactions with other medicines
- Some medicines can affect the way Pantoprazole+Cinitapride works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat your fungal infections, psychiatric illnesses, heart problems, cancer, HIV-infection, or you are taking blood thinners, Methotrexate, Rifampicin, St John's wort, digoxin, painkillers.
Dosage
Overdose
Seek urgent medical help in case you have consumed too much of Pantoprazole+Cinitapride.
Missed a Dose
If you missed any dose of Pantoprazole+Cinitapride, take it as soon as you remember. However, if it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Pantoprazole sodium delayed-release tablets, oral suspension USP [Internet]. Accessdata.fda.gov. 2026 [cited 14 Jun 2026]
- Pantoprazole 40 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 14 Jun 2026]
- Pantoprazole 40 mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 14 Jun 2026]
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