Vicks Action 500 Advanced Tablet
10 Tablet(s) in StripProduct Summary
Vicks Action Advanced 500 mg Tablet is a cold-symptom medicine from Procter & Gamble Hygiene and Health Care used to treat common cold symptoms. It contains paracetamol 500 mg, phenylephrine 5 mg and other cold-symptom ingredients. They reduce pain and fever, narrow swollen nasal vessels, block histamine and support alertness.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 3:39 PM (IST)
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Dose Form
TABLET
Expiry
General Information
Phenylephrine 5.0 Mg+Caffeine 30.0 Mg+Diphenhydramine 25.0 Mg+Paracetamol / Acetaminophen 500.0 Mg

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*Offer applicable on orders above ₹1000About Vicks
Vicks 500 tablet is a cold and flu medicine. It helps relieve symptoms such as a runny or stuffy nose, common cold, sneezing, body aches, headache, dry cough, and fever. The tablet contains a combination of diphenhydramine, phenylephrine, caffeine, and paracetamol.
Some other tablets containing the same active molecules are Nam Cold New tablet, New Hatric 3 tablet, Teplota Cold tablet, Sudin Cold tablet, and Rinostat Plus tablet. It acts by inhibiting the release of the chemical substance histamine. It constricts the nasal blood vessels, thus aiding in clearing the nasal passage and inhibiting the chemical substance involved in pain and fever.
Vicks 500 tablets should not be used in children below 12. Inform the doctor if you are on other medications or have medical conditions. Do not consume more than what is suggested by the doctor. Inform your doctor if you are breastfeeding a baby, intend to get pregnant, or are already pregnant.
Uses
Contraindications
- If you are allergic to paracetamol, phenylephrine, diphenhydramine, caffeine or any other Vicks 500 tablet ingredients.
- If you have a stomach ulcer or obstruction of the stomach and intestine.
- If you have a non-cancerous tumour of the adrenal gland (pheochromocytoma).
- If you have eye conditions such as glaucoma.
- If you have severe liver or kidney disease, high blood pressure, hyperthyroid (overactive thyroid), diabetes and heart disease.
- If you are on antipsychotic medicines (medicines used in brain diseases) such as imipramine, amitriptyline, doxepin, desipramine or beta-blockers (drugs used in high blood pressure) such as metoprolol, propranolol, atenolol.
- If you are or were on Monoamine oxidase inhibitors (MAOIs) such as selegiline, isocarboxazid, phenelzine and tranylcypromine in the past 14 days.
Side effects
- The most common side effects of taking Vicks 500 tablet include:
- Nausea
- Vomiting
- Drowsiness
- Dizziness
- Fatigue
- Dry mouth
- Headache
Precautions and Warnings
Alcohol
UNSAFENo, you should not consume alcohol with Vicks Action 500 Advance tablet. It may increase the side effect of sleepiness and liver damage. Talk to your doctor if you consume it often.
Pregnancy
UNSAFEVicks Action 500 Advance tablet is not recommended during pregnancy. Consult your doctor before using this medicine if you are pregnant or think you may be pregnant.
Breastfeeding
UNSAFEIt is not advisable to breastfeed while taking Vicks Action 500 Advanced Tablets. Some components of this medication may pass into breast milk and could potentially harm a nursing infant. If you are a breastfeeding mother, it's important to inform your doctor.
Driving
UNSAFEVicks Action 500 Advance tablet can make you feel dizzy, drowsiness after taking this medicine. Hence, avoid driving.
Other General Warnings
- You are on other medicines containing paracetamol.
- You are on other cough cold medicines.
- You may have heart or vascular disease such as Raynaud's phenomenon.
- You may consume coffee, tea other product containing caffeine.
- You have liver disease.
Directions for use
Storage and disposal
- Store Vicks 500 tablets at temperature below 25°C in a cool, dry place.
- Keep it out of the reach of children and pets.
Quick tips
- Avoid drinking alcohol while taking this medicine, as it may increase the risk of side effects.
- Do not take Vicks 500 for longer than recommended or in larger doses.
- Eat nutritious foods and increase your intake of fruits, vegetables, and whole grains to improve your condition.
- Get enough sleep and avoid over-exertion. This can help your body recover faster.
- Vicks 500 tablet may not be used by children below 12 years of age.
Dosage
Overdose
Missed a dose
How Vicks works
- Vicks 500 tablet contains phenylephrine, paracetamol, diphenhydramine, and caffeine.
- Phenylephrine is a nasal decongestant; it shrinks or constricts the blood vessels in the nasal passage and improves congestion.
- Diphenhydramine acts by blocking the action of histamine, a natural substance produced by the body during an allergic reaction, and improves allergic symptoms like sneezing, watery eyes, and throat irritation.
- Caffeine acts by increasing alertness and wakefulness.
- Paracetamol acts by inhibiting the synthesis of prostaglandins, which are responsible for causing pain, swelling, and inflammation. Thus, it offers anti-inflammatory properties.
Interactions
Interactions with other medicines
- Vicks 500 tablet can interact with certain medications, potentially increasing the risk of side effects or reducing their effectiveness.
- Antipsychotics: Medications like imipramine, amitriptyline, and doxepin can increase sedation when taken with Vicks 500.
- Cardiovascular Medications: Using Vicks 500 with certain heart medications, such as beta-blockers and digoxin, may increase the risk of heart problems.
- Blood Thinners: Combining Vicks 500 with blood thinners like warfarin can increase the risk of bleeding.
- MAO Inhibitors: Using Vicks Action 500 Advance within 14 days of taking MAO inhibitors can significantly increase the risk of side effects.
- Other Medications: Vicks 500 Advance may also interact with other medications, including lithium.
Food interactions
Frequently asked questions
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References
- U.S. National Library of Medicine. Phenylephrine. MedlinePlus. 2025 [cited 19th Oct 2025]
- Drugs.com. Phenylephrine: Uses, Dosage, Side Effects, Warnings. 2025 [cited 19th Oct 2025]
- MedlinePlus. Diphenhydramine. [Internet]. U.S. National Library of Medicine. 2025 [cited 19th Oct 2025]
- National Institute of Diabetes and Digestive and Kidney Diseases. Diphenhydramine [Internet]. National Institutes of Health; 2025 [cited 19th Oct 2025]
- Drugs.com. Paracetamol [Internet]. 2025 [cited 19th Oct 2025]
- U.S. National Library of Medicine. Acetaminophen [Internet]. National Institutes of Health; 2025 [cited 19th Oct 2025]
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