Melamet Cream
15g Cream in TubeProduct Summary
Melamet Cream is a topical combination used to treat moderate to severe facial melasma, the dark facial patches caused by increased pigment production. Made by Uth Healthcare, it contains hydroquinone 2% w/w, mometasone furoate 0.1% w/w and tretinoin 0.025% w/w, which reduce melanin production and inflammation and increase skin-cell renewal.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 4:49 PM (IST)
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UTH HEALTHCARE
Dose Form
CREAM
Expiry
General Information
| Therapy | Drugs for melasma |
| Composition | Hydroquinone(2.0 %W/W)+Mometasone Furoate(0.1 %W/W)+Tretinoin(0.025 %W/W) Hydroquinone 2.0 %W/W+Mometasone Furoate 0.1 %W/W+Tretinoin 0.025 %W/W |
Hydroquinone 2.0 %W/W+Mometasone Furoate 0.1 %W/W+Tretinoin 0.025 %W/W

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15 days easy return policy
*Offer applicable on orders above ₹1000About Melamet
Melamet cream is a dermatological treatment used for managing melasma, age spots, and dark patches on the skin. It works by reducing excess melanin production, which causes skin darkening. By targeting uneven pigmentation, Melamet helps restore a clearer, brighter skin tone when used correctly under medical guidance.
This cream contains a potent combination of mometasone (a mild steroid), tretinoin (a retinoid), and hydroquinone (a skin-lightening agent). Together, these ingredients help reduce inflammation, promote skin renewal, and help lighten dark spots. However, since it includes a steroid, it should only be used for short periods and strictly as prescribed by your dermatologist.
When using Melamet cream, always apply a thin layer to the affected area at night, as your doctor said. Avoid direct sunlight after application, and use sunscreen during the day to prevent further pigmentation. Overuse or prolonged use without medical supervision may increase the risk of side effects.
Possible side effects include burning, itching, redness, dryness, and mild skin irritation. These are usually temporary, but please consult your dermatologist if reactions worsen or continue. Always inform your doctor about other skin products or treatments you are using to avoid harmful interactions. Pregnant and breastfeeding women should seek medical advice before using Melamet cream.
Other creams with a similar composition of mometasone, tretinoin, and hydroquinone include Eukroma Plus, Melabest, Melacare cream, and Clear Skin. Your doctor may recommend one of these alternatives based on your skin condition and medical history. Always follow your dermatologist’s advice for safe and effective treatment.
Uses
Contraindications
- If you have a known allergy to mometasone, tretinoin, hydroquinone, or any other ingredient of Melamet cream.
- Melamet cream should not be used by a person having skin conditions such as eczema (infected skin due to allergy), rosacea (small red pustules on face), rashes around the mouth (perioral dermatitis) or on damaged skin anywhere in the body.
- Do not use this cream if you have a history of skin tumour, viral or fungal infection of the skin, any ulcers on the skin or tuberculosis.
Side effects
- Itching
- Redness
- Burning
- Irritation
- Thin skin
Precautions and Warnings
Alcohol
SAFEIt is not known if constituents of Melamet cream interacts with alcohol.
Pregnancy
CONTRAINDICATEDMelamet cream should not be used in pregnant women as it has the potential to cause birth defects.
Breastfeeding
UNSAFEIt is not known if the ingredients of Melamet cream pass into the breast milk. It is not recommended to use if you are breastfeeding. In case your doctor prescribes you with this cream, try to use it for the shortest possible duration in small areas of skin.
Driving
SAFEMelamet cream is meant for external application and thus may not affect driving ability.
Other General Warnings
- You have a history of allergic reactions upon application of topical medicines.
- You are pregnant, may be pregnant or breastfeeding.
- You experience skin rashes and infections after the application of Melamet cream.
Directions for use
Quick tips
- This medicine is meant for external application and should not be swallowed. Do not apply to open wounds or weeping areas.
- Do not use more than the recommended amount of this medicine or for longer periods of time than directed.
- Avoid exposure to sun rays after applying Melamet cream.
- Inform your doctor if you have a skin tumour or a family history of skin tumours.
- Melamet cream has no anti-acne or anti-pimple action and should not be used to treat such skin conditions.
- A prolonged application may lead to side effects such as Cushing's syndrome (weight gain, fatty deposits under the skin, moon face, purple patches on the skin, etc.) and increased sugar levels in the blood and urine.
- Avoid exposure to sun rays, as they may be harmful after applying this cream, and use a broad-spectrum sunblock while using this cream.
Dosage
Overdose
- Since Melamet cream is meant for external application, cases of overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital.
- If you have overapplied it, wipe out the excess cream with a clean tissue or cotton. Excessive use for a prolonged duration is not advised as it can lead to hormonal issues.
Missed a dose
How Melamet works
Interactions
Drug interactions of Melamet with other medicine salt
Food interactions
Frequently asked questions
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References
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 11th Nov 2025]
- Drugs H. Tretinoin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [cited 11th Nov 2025]
- NCBI. 2% hydroquinone, 0.025% tretinoin, and 1% mometasone [Internet]. 2025 [cited 11th Nov 2025]
- Drugs H. Mometasone Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [cited 11th Nov 2025]
- Hydroquinone Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD [Internet]. Webmd.com. 2025 [cited 11th Nov 2025]
- Cleveland Clinic. Hydroquinone (skin cream, gel, emulsion, lotion, or solution) [Internet]. Cleveland Clinic; 2025 [cited 11th Nov 2025]
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