VYMADA 50MG TABLET

• If you are allergic to sacubitril, valsartan or any other ingredients of Vyamda 50.
• If you have diabetes or kidney disease and taking aliskiren-containing blood pressure-lowering medicine.
• If you have severe liver disease.
• If you are pregnant and pregnancy is of more than 3 months.
• If you are taking any medicines from the angiotensin-converting enzyme (ACE) inhibitor group of medicine used for the treatment of high blood pressure or heart failure, you should wait for at least 36 hours after taking the last dose, before taking Vymada 50mg tablet.
• If you or any member of your family has a history of swelling of lips, face, tongue, or throat after taking any medicine from the ACE inhibitor group of medicine or angiotensin II receptor blocker group of medicine.

• Dizziness
• Light-headedness
• Nausea
• Headache
• Fainting
• Loose motions
• Cough
• Tiredness or weakness
• Pain in stomach
• Spinning sensation

Other General Warnings

• You are taking medicines such as aliskiren and any medicine from the angiotensin II receptor blocker group of medicine.
• You have swelling of lips, face, tongue, and throat after taking this medicine.
• You have low blood pressure or taking any other medicine to lower blood pressure.
• You have vomiting, loose motions or has dehydration, and your age is more than 65 years.
• You have kidney disease and low blood pressure.
• You have severe kidney disease or liver disease.
• Your kidney artery has been narrowed.

• Take this medicine with or without food as prescribed by your doctor.
• Do not stop taking Vymada 50mg tablet on your own.
• Take it regularly at the same time for optimal results.

• Store Vymada 50mg tablet at room temperature and away from light.
• Keep away from children and pets. Store this medicine in the original package to protect it from moisture.

• Vymada 50 mg table is used in the treatment of heart failure in patients having a type of long-term heart failure.
• Take Vymada 50 as prescribed by your doctor for the prescribed duration. Do not skip or miss the dose of Vymada 50mg.
• If you stop taking Vymada suddenly, it may worsen the disease condition.
• Inform your doctor if you have a history of liver or kidney diseases.
• Dizziness, light-headedness, nausea, headache and fainting are a few common side effects of Vymada. These side effects are usually mild and resolve with time.

Overdose

Missed a Dose

How Does It Work?

• Sacubitril lowers blood pressure by causing blood vessel relaxation, excretion of sodium through urine and increasing urination.
• Valsartan works by relaxation of blood vessels so that the heart pumps blood more easily through blood vessels to the body.

Interactions with other medicines

• Vymada 50mg can interact with several other medications, potentially leading to serious side effects.
• ACE Inhibitors: Combining Vymada with ACE inhibitors (like enalapril or lisinopril) significantly increases the risk of angioedema, a severe allergic reaction causing facial swelling.
• Aliskiren: Concomitant use with aliskiren (another blood pressure medication) can dangerously lower blood pressure, increase potassium levels, and impair kidney function.
• Sildenafil (Viagra): Combining Vymada with sildenafil can further decrease blood pressure, potentially causing dizziness or fainting.
• Potassium-Sparing Diuretics: Medications like triamterene, amiloride, spironolactone, and eplerenone, along with potassium supplements or salt substitutes, can increase potassium levels when taken with Vymada.
• NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): In elderly individuals with dehydration or kidney disease, combining Vymada with NSAIDs (like ibuprofen or naproxen) can worsen kidney function.

Interactions with food items