Voltapraz 20 Tablet

• Voltapraz tablet is used to heal damage to the esophagus caused by excess stomach acid (erosive esophagitis) and alleviate associated heartburn.
• It also helps maintain healing and prevent recurrence of heartburn after the esophagus has healed. When prescribed with other antibiotics (such as amoxicillin alone or amoxicillin and clarithromycin), it helps eliminate Helicobacter pylori bacteria.

• Do not take Voltapraz tablet if:
• You are allergic to vonoprazan or any of the other ingredients of this medicine. Allergic reactions to vonoprazan have included severe reactions such as anaphylaxis.
• You are taking rilpivirine-containing medicines (used to treat HIV). Because Voltapraz tablet reduces stomach acid, it can make rilpivirine less effective.

• Gastritis (irritation of the stomach lining)
• Diarrhoea
• Abdominal bloating or fullness
• Stomach pain
• Nausea
• Indigestion
• Headache
• Altered sense of taste (more likely when taken with antibiotics for H. pylori)
• Vaginal yeast infection (thrush) or urinary tract infection (when used with antibiotics for H. pylori)

• Severe skin reactions (spreading rash, blistering, peeling skin, or mouth sores)
• Serious allergic reactions (swelling of the face, lips, or throat, or difficulty breathing)
• Persistent or severe watery diarrhoea
• Signs of kidney problems
• Signs of low magnesium (muscle cramps, tremors, or an irregular heartbeat)

• Take Voltapraz tablet exactly as prescribed by your doctor. Swallow the tablet whole with enough water. Do not chew or crush it. It can be taken with or without food. Vonoprazan is available as 10 mg and 20 mg tablets; your doctor will decide the strength, dose, and duration based on your condition.
• Erosive esophagitis is usually treated for several weeks, sometimes followed by a lower maintenance dose, while Helicobacter pylori infection is treated together with antibiotics for a shorter, fixed course. Complete the full course even if you feel better.

• Inform your doctor if you have low magnesium or other mineral levels, or low vitamin B12 levels. If you are undergoing long-term treatment (more than one year) with this medication, it may decrease magnesium levels or lead to bone weakness. Consult your doctor to determine if you may need supplements to address these deficiencies.
• Also, tell your doctor if you have any issues with your bones, kidneys, or liver.
• You can make lifestyle changes, such as avoiding excessive intake of acidic foods (including carbonated drinks and oily or fried foods), exercising regularly, and maintaining a healthy weight.
• It is also advisable to limit alcohol intake and quit smoking to improve the treatment of your acid reflux.
• Raise the head of the bed and leave a gap between your last meal and bedtime if night-time reflux is the problem.
• Consult a doctor immediately if you have difficulty swallowing, unintended weight loss, vomiting blood, or black stools. These need investigation, not stronger acid treatment.
• Ask before adding an anti-inflammatory painkiller, which is a common reason acid problems come back.

Overdose

Missed a Dose

Interactions with other medicines

• Some medicines can affect Voltapraz tablet, which can affect how they work. Tell your doctor about all the medicines, supplements, and herbal products you take. In particular:
• Rilpivirine (HIV medicine) - must not be taken with this medicine.
• Atazanavir, nelfinavir, and other HIV medicines - Voltapraz tablet can change how well they are absorbed; your doctor may avoid combining them.
• Medicines that need stomach acid to be absorbed, such as iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, and ketoconazole/itraconazole - Voltapraz tablet may reduce their effect.
• Clopidogrel (used to prevent blood clots) - Voltapraz tablet may reduce how well clopidogrel works, so your doctor may monitor you or suggest an alternative.
• Citalopram (an antidepressant) and cilostazol - their levels may rise, so your doctor may watch for side effects.
• Digoxin and water pills (diuretics) - relevant if your magnesium level drops (see warnings).
• Medicines that speed up drug breakdown in the liver (strong CYP3A4 inducers) - these can make Voltapraz tablet less effective and are usually avoided.
• Tell your doctor, especially if you are taking medicines for HIV/AIDS.

Interactions with food items

• You can take it with or without food
• Cut down on triggers rather than relying on the tablet alone. Common triggers include spicy and fried food, very acidic food, caffeine, and fizzy drinks.
• Avoid alcohol while the gullet or stomach lining is healing. It irritates the lining and works against the treatment.
• Avoid eating late at night and lying down soon after a meal, which lets acid track upwards.

Other general Interactions