Unitrexate 50mg Injection 2ml

• If you are allergic to Methotrexate or any other component of Unitrexate Injection.
• If you are pregnant and breastfeeding.
• If you have severe liver or kidney disease.
• If you have pre-existing blood disorders such as decreased platelets and white blood cells.

• Diarrhoea
• Mouth ulcers
• Weakness
• Menstrual problems
• Skin rashes
• Persistent cough
• Pain in joints, muscles and stomach
• Swelling of feet
• Dizziness
• Yellowing of the skin (an indication of liver damage)
• Fever with chills
• Unusual bleeding
• Blurred vision
• Temporary hair loss
• Loss of appetite
• Difficulty in passing urine
• Nausea or vomiting
• Decrease white blood cells

Other General Warnings

• You have liver, kidney or bone marrow disease.
• You are pregnant or planning pregnancy and breastfeeding.
• You have any known medical condition.
• You are on any other medication or therapy.
• You have stomach-intestinal or lung disease or conditions such as ulcers, persistent cough.
• You have taken any vaccination recently (live vaccine).
• You experience any skin reaction or other side effect after taking this medicine.
• Unitrexate Injection should not be used in children below 3 years of age.

• Unitrexate Injection will be given by a doctor or nurse in a hospital/clinic.
• Do not self-inject. Follow any aftercare instructions given by the doctor/nurse.

• Store Unitrexate Injection at a temperature not exceeding 30 °C in the original package to protect from light. Do not freeze.
• Expired or unused medication should be disposed of via proper waste management protocol suggested by a pharmacist.

Overdose

• The overdose of Unitrexate Injection can cause vomiting, diarrhoea and gastrointestinal bleeding, severe bone marrow suppression, liver toxicity (more likely in patients with pre-existing risk factors for liver disease), sudden shortness of breath and a dry, persistent cough, and fever. A single overdose has also shown a fatal side effect. Another cause of death is bone marrow suppression.
• Several deaths have been reported all over the world from methotrexate overdose because of accidentally taking the injection daily instead of once a week dose as prescribed.
• This injection will be given by a doctor or nurse. Thus, the chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the nearest hospital.

Missed a Dose

How Does It Work?

Interactions with other medicines

• Some medicines can affect the way Unitrexate Injection works or the Unitrexate itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Especially, if you are taking painkiller medicines to provide relief from pain such as aceclofenac, ibuprofen, diclofenac or other immunomodulatory medicines such as cyclosporine.
• When the Unitrexate Injection is administered during the period of radiotherapy, it may increase the risk of cell death in soft tissues and bones.
• If you have recently take any live vaccines, this medicine may alter the effectiveness of medicine.