Trikozine Plus Tablets
By TRIKO PHARMACEUTICALS
10 Tablet(s) in Strip
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Description
Trikozine Plus tablet is a prescription medicine. It is used to manage the symptoms of schizophrenia (a mental disorder), Parkinson’s disease (a central nervous system disorder that causes movement p
roblems and tremors), and anxiety. The active ingredients in Trikozine Plus Tablets are trifluoperazine and trihexyphenidyl. Trifluoperazine belongs to the class of antipsychotic medications. The mode of action of Trikozine Plus Tablets is to block certain receptors and improve behaviour and mood. However, trifluoperazine causes side effects like involuntary limb shaking and muscle spasms. Trihexyphenidyl is added to Trikozine Plus Tablets to prevent and manage these side effects. Direction for use of Trikozine Plus Tablets should be strictly followed. Most of the side effects of Trikozine Plus Tablets do not require any medical intervention as they subside gradually. However, the doctor should be alerted in case of persistent or worsening symptoms. Abrupt stoppage of this medicine can cause sweating, nervousness, vomiting, dizziness, etc.
Product Summary
| Offer Price | ₹15.00 |
| You Save | ₹5.00 (25% on MRP) |
| Contains | Trifluoperazine(5.0 Mg)+Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg) |
| Uses | Schizophrenia, Parkinson's disease, Anxiety |
| Side effects | Nausea, Weight gain, Constipation, Sedation, Orthostatic hypotension (sudden lowering of blood pressure on standing), Dryness in mouth, Increased prolactin level in the blood, Urinary retention, Dizziness, Blurred vision. |
| Therapy | ANTI-PSYCHOTICS |
Uses
- As per CDSCO, the Trikozine Plus tablet is used for:
- Managing positive and negative symptoms of schizophrenia (reduces strong and inappropriate symptoms, disturbed/unusual thinking, etc.)
- Treatment of symptoms associated with Parkinson’s disease (reduces involuntary movements)
- Treatment of neurosis (a mental disorder) as a psychoneurotic medicine
Contraindications
- Do not take Trikozine Plus Tablets, or use caution:
- If you have known hypersensitivity to any of the ingredients of the Trikozine Plus tablet.
- If you are pregnant; Trikozine Plus Tablet can adversely affect the foetus, especially if taken in the third trimester.
- If you are nursing; consult your doctor before taking Trikozine Plus Tablet.
- If you have severe central nervous system (CNS) depression (slow and steady decline of breathing).
- If you have narrow-angle glaucoma (a condition with increased pressure in the eye); this medicine worsens this condition.
- If you are already suffering from conditions like tardive dyskinesia (involuntary face movements).
- If you have dementia (memory loss); this medicine can increase the side effects and cause death. Dose adjustment is required.
- If you have infectious diarrhoea; Trikozine Plus Tablet makes eliminating bacteria difficult.
- If you have not reached adulthood. This medicine is not meant for children under 18.
- If you have a urinary problem; Trikozine Plus medicine can worsen it.
Side effects
- Side effects of Trikozine Plus Tablets include:
- Nausea
- Constipation
- Dizziness
- Weight gain
- Dry mouth
- Blurred vision
- Urinary retention
- Orthostatic hypotension (sudden fall in blood pressure with position change)
Precautions and Warnings
Pregnancy
Q:
Can I take the Trikozine Plus tablets during pregnancy?
A:
Consult your doctor before taking a Trikozine Plus tablet if you are pregnant. There is limited data on the safety of this medicine in pregnant women, but animal research has shown some harmful effects on the foetus.
Breast Feeding
Q:
Can I take the Trikozine Plus tablets while breastfeeding?
A:
Do not take this medicine while breastfeeding unless explicitly advised by a doctor. There is insufficient data on the effects of this medicine on breastfed babies and their mothers. However, it is likely that this medicine passes into breast milk and has unwanted effects on the baby.
Driving
Q:
Can I take the Trikozine Plus tablets during pregnancy?
A:
Do not drive after taking the Trikozine Plus tablet. The medicine may cause side effects that affect your ability to drive or operate heavy machinery. In some cases, you may experience blurring of vision, dizziness, mental confusion, nausea (mild), drowsiness, and other side effects.
Alcohol
Q:
Can I consume alcohol with the Trikozine Plus tablet?
A:
Do not consume alcohol with Trikozine Plus tablet. This medicine exaggerates the effects of alcohol. They can interact and cause side effects like lightheadedness, nausea, vomiting, loss of consciousness, dizziness, etc.
Other General Warnings
Talk to your doctor if
- You have hypertension or high blood pressure. This medicine can further increase blood pressure.
- You have seizure syndrome. Use extreme caution, as this medicine can increase the risk of seizures.
- You are an older adult. Dose adjustment is needed to prevent excessive side effects due to slow metabolism in this age group.
- You have been out in the sun for a long time. This medicine can cause heatstroke.
- You use any herbal or Ayurvedic medicines and supplements.
- You suddenly stopped using Trikozine Plus Tablets. This can cause neuroleptic malignant syndrome (fever, altered mental status, muscle stiffness, etc.).
Mode of Action
How Does It Work?
The Trikozine Plus tablet has two active ingredients: trifluoperazine and trihexyphenidyl/benzhexol.
Trifluoperazine belongs to the class of conventional or typical antipsychotic medications. It works by blocking dopamine receptors in the body. This results in the decreased effect of dopamine (a natural chemical substance in the body). Dopamine is responsible for affecting the quality of thoughts and mood. It also lowers the effects of hallucination and delusions.
Trihexyphenidyl or benzhexol hydrochloride belongs to the class of medicines called antispasmodics. It blocks acetylcholine receptors, a natural chemical substance in the body. It acts on the central nervous system. It reduces symptoms like involuntary shaking of arms and legs, muscle spasms, etc., which are the side effects of trifluoperazine. Trihexyphenidyl is added to Trikozine Plus Tablet to reduce the side effects of trifluoperazine. Trihexyphenidyl also lowers muscle stiffness and excess production of saliva and sweat....
Directions for Use
- Take Trikozine Plus Tablets in the recommended dose and duration.
- You can have these tablets with or without meals. Take it with food in case of stomach issues.
- Do not take more than a single tablet at one time without informing the doctor, as this can lead to an overdose.
- Use it immediately after opening the package.
- Try to swallow the tablet entirely with a glass of water, and do not break or chew the tablet.
- Try to take this medication on time.
- Check the expiration date before using this medicine.
- Consult the doctor if you want to give it to a child under 18. This medicine is not indicated for this age group.
Interactions
Interactions with other medicines
- Trikozine Plus Tablets can interact with many medicines and cause adverse side effects. It is advised to inform the doctor of all current medication to be checked for possible interaction issues. The following medicines are known to interact with Trikozine Plus Tablets....
- Do not take Trikozine Plus Tablets if you already use high blood pressure medication. This medicine can further increase blood pressure.
- Use of Trikozine Plus Tablets with opioid or narcotic pain relievers can cause drowsiness.
- If you use medicines that lower lung secretions or saliva, Trikozine Plus Tablets will negate the effects of those medicines.
- Do not use other antipsychotics, anticonvulsants, and anti-Parkinsonian medicines with Trikozine Plus Tablets. It can cause adverse reactions.
- Trikozine Plus Tablets also interact with other medicines like antihistamines (allergy medicine), blood thinners (warfarin), heart medicines, and fever-reducing medicines.
Storage and disposal
Store Trikozine Plus Tablets at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the tablets. Dispose of the packaging carefully after use. Do not flush extra or expired pills down the toilet. Dispose of unused or expired medicine as biomedical waste....
Dosage
Overdose
Trikozine Plus tablet overdose can cause severe drowsiness, dry mouth, abdominal pain, dizziness, fainting, vomiting, seizures, hallucination, sweating, cardiac arrest, agitation, involuntary movement of the muscles, liver failure (yellow skin and eyes), loss of consciousness, etc. In case of Trikozine Plus tablet overdose, seek immediate medical treatment from the nearest medical centre....
Missed a Dose
If you have missed a dose of Trikozine Plus tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regular dosing schedule. Do not take both of them together; this can lead to adverse reactions....
Content Details
WRITTEN BY
REVIEWED BY
Dr. Varsha Parihar
MBBS, MD (Community Medicine)
Frequently Asked Questions (FAQs)
Q: Can I stop taking Trikozine Plus tablets if I start feeling better?
A: Do not stop taking this tablet even if you feel well. If you suddenly stop using Trikozine Plus Tablet, serious withdrawal problems may occur. The dose needs to be slowly tapered by the doctor before stopping completely
Q: Will I gain weight if I use Trikozine Plus tablets daily?
A: Weight gain is one of the side effects of this tablet. To avoid this, try exercising regularly and maintaining a healthy lifestyle.
Q: Can Trikozine Plus tablets cause heatstroke?
A: Trikozine Plus tablets can reduce sweating. This results in a rise in body temperature (hyperthermia), leading to heatstroke. This side effect is greater in hot weather, so drinking a lot of fluids is recommended, especially in the summertime. However, people with a kidney disorder should consult a doctor before drinking excessive liquids.
References
View All
- Trifluoperazine: MedlinePlus Drug Information [Internet]. MedlinePlus. U.S. National Library of Medicine [cited 17 Mar 2022] -
- New Drugs Approved by CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 17 Mar 2022] -
- Trihexyphenidyl: MedlinePlus Drug Information [Internet]. MedlinePlus. U.S. National Library of Medicine [cited 17 Mar 2022] -
- Dabhade SL, Shetty AS, Ahmed M, Gopinath B, Sridhar K, Sureja ML. Simultaneous estimation of Trifluoperazine hydrochloride and Trihexyphenidyl hydrochloride in combined dosage form BY RP-HPLC method [Internet]. Int. J. Chem. Sci. 2010. 8(3): 1684-1694 [cited 17 Mar 2022] -
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Product Details
Brand
TRIKOZINE PLUS
Expiry Date
28/01/2026
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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