Metital Strip Of 15 Tablets

• Metital tablet is used in the management of polycystic ovary syndrome (PCOS) in women with insulin resistance. It improves the body's sensitivity to insulin and helps regulate glucose metabolism.
• Helps restore regular menstrual cycles. Supports ovulation and ovarian function. It is intended to be used alongside dietary changes, regular exercise, and weight management, as advised by your doctor.

• Metital tablet should not be taken if you:
• Are allergic to metformin, myo-inositol, or any other ingredient of Metital tablet.
• Have severe kidney disease or reduced kidney function.
• Have diabetic ketoacidosis or diabetic pre-coma.
• Have any acute condition that can affect kidney function, such as severe dehydration, severe infection, or shock.
• Have a condition that reduces oxygen supply to the tissues, such as decompensated heart failure, respiratory failure, a recent heart attack, or shock.
• Have severe liver disease.
• Have acute alcohol intoxication or alcohol dependence.

• Diarrhoea
• Nausea and vomiting
• Abdominal pain or stomach discomfort
• Loss of appetite
• Metallic taste in the mouth
• Bloating or flatulence

Other General Warnings

• You have kidney disease or reduced kidney function. Your doctor will check your kidney function before starting treatment and at least once a year afterwards, or more often if needed.
• You have liver disease.
• You have heart failure or have had a recent heart attack.
• You are scheduled for surgery under general, spinal, or epidural anaesthesia. Metital tablet usually needs to be stopped before the procedure and restarted only after your kidney function has been reassessed.
• You are due to have a scan or X-ray involving contrast dye.
• You develop a serious infection, severe diarrhoea or vomiting, or become dehydrated, as these can affect kidney function. Contact your doctor, as treatment may need to be paused.
• You drink alcohol regularly or heavily.
• You have thyroid problems, as thyroid disorders can cause symptoms similar to PCOS.
• You are taking this medicine long-term, as vitamin B12 levels may need to be monitored.
• You develop any allergic reaction after taking Metital tablet.
• You do not notice any improvement in your symptoms. Menstrual regularity often takes three to six months to improve.
• Do not use Metital tablet for any condition other than that prescribed by your doctor, and do not share it with anyone else.

• Drink plenty of water and consume fibre-rich foods to alleviate constipation.
• If side effects persist or worsen, consult a healthcare professional.
• Do not exceed the recommended dose unless advised by a doctor.
• Use under medical supervision.
• Keep out of reach of children.

Overdose

Missed a Dose

• Metital tablet contains two agents that improve insulin sensitivity through complementary mechanisms.
• Metformin reduces glucose production by the liver, decreases intestinal glucose absorption, and increases the body's response to insulin. This lowers circulating insulin levels.
• Myo-inositol acts as a second messenger in insulin signalling inside the cell. In women with PCOS, improving this signalling pathway supports ovarian function and follicular development.
• Together, they help reduce elevated insulin levels and reduce excess ovarian androgen production. This supports hormonal balance, more regular menstrual cycles, and ovulation.

Interactions with other medicines

• Some medicines can affect how Metital tablet works, and Metital tablet can affect how other medicines work.
• Inform your doctor about all medicines, supplements, and herbal products you are taking or plan to take.
• Particular care is needed with iodinated contrast dye used in CT scans, angiography and some X-rays. Metital tablet should be stopped before the procedure and for 48 hours afterwards, as the combination can affect kidney function and increase the risk of lactic acidosis.
• Particular care is needed with medicines that can affect kidney function, including painkillers such as ibuprofen and diclofenac, blood pressure medicines such as ACE inhibitors and ARBs, and diuretics (water pills).
• Particular care is needed with insulin and other antidiabetic medicines such as sulfonylureas, which increase the risk of low blood sugar.
• Particular care is needed with corticosteroids, salbutamol and similar medicines, and some decongestants, which can raise blood glucose levels.
• Particular care is needed with alcohol, which increases the risk of lactic acidosis.
• Particular care is needed with cimetidine, dolutegravir, ranolazine and certain other medicines that compete with metformin for removal by the kidneys.
• Tell your doctor or dentist that you are taking Metital tablet before any surgery, or before any scan involving contrast dye.