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Methotraxete 50mg Vial Of 2ml Injection

By VENUS REMEDIES LTD
2ml Injection in Vial

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Methotrexate 50 MG Description

Methotrexate Injection has varied used based on conditions such as 'Immunosuppressant action' against psoriasis and rheumatoid arthritis while 'Anti-neoplastic' action against various types of cancer

. It contains methotrexate as its active ingredient. It acts by suppressing the immune response, reducing the swelling, stiffness and inflammation along with slowing down the skin proliferation in rheumatoid arthritis and psoriasis respectively, whereas it inhibits or slows down the growth of cancerous cells in various types of cancer. Methotrexate Injection is given under the medical supervision of a doctor or nurse at the hospital or clinic setup. It should not be consumed orally. It should not be used in pregnant and breastfeeding women. Inform your doctor about all the medical conditions and medication you have or had.

modeOfAction

Product Summary

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ContainsMethotrexate(50.0 Mg)
UsesPsorasis, Rheumatoid arthritis, Cancer
Side effectsDiarrhoea, Ulcer, Weakness, Cough
TherapyANTI-NEOPLASTIC
molecules
Check more medicines with composition as Methotrexate(50.0 Mg)
uses

Uses of Methotrexate 50 MG

Methotrexate Injection is used to treat varied conditions such as psoriasis, rheumatoid arthritis and various types of cancers such as breast and lung cancers.
contraindications

Contraindications of Methotrexate 50 MG

  • If you are allergic to Methotrexate or any other component of Methotrexate Injection.
  • If you are pregnant and breastfeeding.
  • If you have severe liver or kidney disease.
  • If you have pre-existing blood disorders such as decreased platelets and white blood cells.
sideEffects

Side effects of Methotrexate 50 MG

  • Diarrhoea
  • Mouth ulcers
  • Weakness
  • Menstrual problems
  • Skin rashes
  • Persistent cough
  • Pain in joints, muscles and stomach
  • Swelling of feet
  • Dizziness
  • Yellowing of the skin (an indication of liver damage)
  • Fever with chills
  • Unusual bleeding
  • Blurred vision
  • Temporary hair loss
  • Loss of appetite
  • Difficulty in passing urine
  • Nausea or vomiting
  • Decrease white blood cells
precautionsAndWarnings

Precautions and Warnings of Methotrexate 50 MG

pregnancy

Pregnancy

Q:
Can Methotrexate Injection be administered during pregnancy?
A:
Methotrexate Injection is not recommended during pregnancy as it can lead to threatened pregnancy along with causing serious harm to the unborn baby. Women of childbearing age should strictly use contraception and avoid pregnancy during its administration period. Inform your doctor if you are pregnant, think you may be pregnant or planning a pregnancy.
breastfeeding

Breast Feeding

Q:
Can Methotrexate Injection be taken during breastfeeding?
A:
Methotrexate Injection should not be administered during breastfeeding as it can cause harm to the newborn baby. Inform your doctor if you are a nursing mother.
driving

Driving

Q:
Can I drive after the administration of Methotrexate Injection?
A:
Do not drive until your vision is clear as the administration of Methotrexate Injection may cause dizziness and drowsiness.
alcohol

Alcohol

Q:
Can I consume alcohol after the administration of Methotrexate Injection?
A:
Alcohol should not be consumed with Methotrexate Injection, as it can increase the side effect. Inform your doctor if you consume it often.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have liver, kidney or bone marrow disease.
  • You are pregnant or planning pregnancy and breastfeeding.
  • You have any known medical condition.
  • You are on any other medication or therapy.
  • You have stomach-intestinal or lung disease or conditions such as ulcers, persistent cough.
  • You have taken any vaccination recently (live vaccine).
  • You experience any skin reaction or other side effect after taking this medicine.
  • Methotrexate Injection should not be used in children below 3 years of age.
modeOfAction

Mode of Action of Methotrexate 50 MG

How Does It Work?

The composition of Methotrexate Injection works by stopping or slowing down the growth of cancer cells and suppressing the immune system. In patients with rheumatoid arthritis, it reduces the activity...
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directionsForUse

Directions for Use of Methotrexate 50 MG

  • Methotrexate Injection will be given by a doctor or nurse in a hospital/clinic.
  • Do not self-inject. Follow any aftercare instructions given by the doctor/nurse.
interactions

Interactions of Methotrexate 50 MG

Interactions with other medicines

  • Some medicines can affect the way Methotrexate Injection works or the Methotrexate itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially, if you are taking painkiller medicines to provide relief from pain such as aceclofenac, ibuprofen, diclofenac or other immunomodulatory medicines such as cyclosporine.
  • When the Methotrexate Injection is administered during the period of radiotherapy, it may increase the risk of cell death in soft tissues and bones.
  • If you have recently take any live vaccines, this medicine may alter the effectiveness of medicine.
storageAndDisposal

Storage and disposal of Methotrexate 50 MG

  • Store Methotrexate Injection at a temperature not exceeding 30 °C in the original package to protect from light. Do not freeze.
  • Expired or unused medication should be disposed of via proper waste management protocol suggested by a pharmacist.
dosage

Dosage of Methotrexate 50 MG

Overdose

  • The overdose of Methotrexate Injection can cause vomiting, diarrhoea and gastrointestinal bleeding, severe bone marrow suppression, liver toxicity (more likely in patients with pre-existing risk facto...
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  • Several deaths have been reported all over the world from methotrexate overdose because of accidentally taking the injection daily instead of once a week dose as prescribed.
  • This injection will be given by a doctor or nurse. Thus, the chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the ne...
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Missed a Dose

It is unlikely that the dose of this injection will be missed if you are monitored in a healthcare set up. However, if you have missed taking any dose of this injection, inform your doctor or nurse im...
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Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

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Q: What precautions should I take before treatment with Methotrexate?

A: The use of the medicine for a prolonged duration may cause liver damage, including cirrhosis (irreversible scarring of the liver), which may be fatal. High doses of this injection can also damage the kidneys and cause their failure. This injection may not be suitable for individuals with psoriasis or rheumatoid arthritis if they: are alcoholics, have alcoholic liver disease or other chronic liver diseases; have an immunodeficiency syndrome; and have a blood deficiency disorder, such as low red blood cell counts, low white blood counts and low blood platelet counts.

Q: Can Methotrexate cause weight gain?

A: The side effects of Methotrexate Injection are nausea, diarrhoea and an upset stomach, which may cause loss of weight.

Q: Is Methotrexate Injection a steroid?

A: No, Methotrexate Injection is not a steroid. It is an immunosuppressant and anti-neoplastic medicine.

Q: Can this medicine cause infections?

A: This medicine is known to affect the immune system that can lead to some serious infections. Consult your doctor for more details about the same.

Q: What precaution should be taken if the expired dosage of Methotrexate is administered?

A: The administration of this injection is limited to a healthcare professional only. However, if expired injection has been administered to you, you should consult your doctor immediately.
Product Details
Brand
METHOTREXATE
Country of Origin
India
Last Updated on: 10 Jan 2023 | 01:04 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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