Met Xl Trio 50Mg Strip Of 15 Tablets

• Met Xl Trio tablet is used to treat uncontrolled essential hypertension (high blood pressure).
• It is also indicated for the management of stable ischemic heart disease.

• You are allergic to metoprolol, cilnidipine, telmisartan, or any other ingredient in this medicine.
• You have severe heart problems, such as sinus bradycardia (heart rate less than 45 beats per minute), second- or third-degree heart block, cardiogenic shock, or uncontrolled heart failure.
• You have an obstruction of blood outflow from the left ventricle of the heart (such as high-grade aortic stenosis).
• You have low blood pressure (hypotension).
• You have reduced blood supply to your limbs (severe peripheral arterial circulatory disorders).
• You have severe asthma or a history of severe bronchospasm or chronic obstructive pulmonary disease (COPD).
• You have severe liver disease or a blockage in the ducts that carry bile from your liver to your gallbladder (obstructive biliary disorders).
• You experience difficulty passing urine or are completely unable to urinate (anuria).
• You have diabetes associated with frequent episodes of low blood sugar (hypoglycemia).
• You have diabetes or impaired kidney function (GFR < 60 mL/min/1.73 m²) and are currently taking aliskiren.
• You have metabolic acidosis (increased acidity in your blood) or are taking medications that stimulate heart contractions through beta-receptors.
• You have an untreated adrenal gland tumor (phaeochromocytoma).
• You are in the second or third trimester of pregnancy.

• Tiredness and fatigue
• Slow heart rate (bradycardia)
• Dizziness or lightheadedness
• Headache
• Swelling in the legs, ankles, or feet (peripheral edema)
• Flushing (warmth or redness of the face and skin)
• Back pain and muscle cramps (myalgia)
• Upper respiratory tract infections, sore throat, or cough
• Nausea, vomiting, or abdominal pain
• Diarrhea or constipation
• Shortness of breath
• Low blood pressure when standing up suddenly (orthostatic hypotension)

Other General Warnings

• You have kidney disease, have had a kidney transplant, or have mild-to-moderate liver disease (severe liver disease is contraindicated).
• You have known narrowing of the blood vessels supplying one or both kidneys (renal artery stenosis).
• You experience dehydration, vomiting, or diarrhea, which can cause your blood pressure to drop too low. Ensure you stay properly hydrated.
• You have a circulation problem in your arms, legs, fingers, or toes (peripheral vascular disease), as beta-blockers can aggravate symptoms of poor blood flow.
• Do not stop taking Met Xl Trio tablet abruptly without your doctor's advice. Sudden discontinuation, especially if you have ischemic heart disease, can cause severe chest pain (angina) or even a heart attack. If the medication needs to be stopped, your doctor will reduce the dose gradually over 1 to 2 weeks.
• Inform your doctor, surgeon, or dentist that you are taking this medication before undergoing any surgical procedure or general anesthesia.
• Consult your doctor immediately if you have heart failure and experience warning signs of worsening heart failure, such as rapid weight gain or increasing shortness of breath.
• Report to your doctor immediately if you develop sudden, severe abdominal pain, nausea, vomiting, or persistent diarrhea, as this may indicate a condition called intestinal angioedema.
• If you have diabetes or an overactive thyroid gland (hyperthyroidism), this medicine may hide certain warning signs, like a fast heartbeat (tachycardia). However, other warning signs of low blood sugar, such as sweating, are usually not affected.

• Take Met Xl Trio tablet exactly as directed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• Take it preferably with or immediately following meals.
• Always take it at the same time each day for the best results.
• Never change the dose or stop taking this medicine abruptly on your own.

• Store Met Xl Trio tablet at a temperature not exceeding 30°C.
• Keep it protected from light and moisture, preferably stored in its original Alu-Alu blister packaging.
• Ensure it is kept out of the sight and reach of children.
• Do not use this medication after the expiry date mentioned on the package.

• Swallow this medicine whole with a glass of water; never chew, break, or crush it.
• Take Met Xl Trio tablet at the exact same time every day, preferably with or immediately after a meal.
• Never stop taking this medicine suddenly on your own. Doing so can cause a dangerous spike in blood pressure, severe chest pain, or heart complications.
• In addition to taking your medication on time, make healthy lifestyle changes: eat a low-salt, low-fat diet; maintain a healthy weight; exercise moderately for 30 minutes daily (as advised by your doctor); quit smoking; and avoid alcohol.
• If you feel dizzy or lightheaded when standing up (orthostatic hypotension), get up slowly from a sitting or lying position.
• Stay well-hydrated; if you suffer from severe diarrhea or vomiting, consult your doctor, as dehydration can cause your blood pressure to drop too low.

Overdose

• Symptoms of an overdose may include severe low blood pressure (hypotension), extremely slow heartbeat (severe bradycardia), dizziness, difficulty breathing or wheezing (bronchospasm), irregular heart rhythms (AV block), heart failure, cardiogenic shock, loss of consciousness, or coma.
• In the event of an overdose, contact your doctor immediately or visit the nearest hospital emergency department.

Missed a Dose

Interactions with other medicines

• Inform your doctor about all the medications, supplements, or herbal products you are taking to avoid any potential interactions.
• Especially if you are taking medicines to treat high blood pressure, heart failure, high cholesterol levels, anticoagulants, antifungals, antidiabetics, antihistamines, analgesics, immunomodulators, or medicines for brain-related disorders.
• Do not take it with medications such as Amiodarone or Disopyramide, or with painkillers such as Indomethacin, Sulindac, Diclofenac, or Focetan, as these can decrease the effect of Met Xl Trio tablet.
• If you have diabetes, dose adjustment may be needed as this medicine can cause a drop in blood glucose levels, and close glucose monitoring is advised.
• Medicines used to treat high blood pressure and benign prostatic hyperplasia (Prazosine, Tamsulosin, Terazosin, and Doxazosin)
• If you have diabetes and you are on Aliskiren, do not take this medicine.
• Caution is needed if you are taking Fluoxetine, Lithium, Paroxetine, Bupropion, Thioridazine (medicines for psychiatric illness), Diphenhydramine, Hydroxychloroquine, and Mefloquine.
• Medicines used to treat acidity or ulcers (antacids), like Cimetidine
• General anaesthetics or local anaesthetics (Lidocaine)
• Medications that may increase blood potassium levels, like salt containing potassium and potassium-sparing diuretics
• Medicines used to treat infections like Trimethoprim, Rifampicin or Terbinafine
• Medicines known as Diuretics (water pills) are used to treat high blood pressure, such as Furosemide and Hydrochlorothiazide

Interactions with food items

• Take Met Xl Trio tablet preferably with or immediately following meals, exactly as directed by your doctor.
• It is advisable to limit foods high in potassium, such as spinach, broccoli, and bananas, as Telmisartan can increase blood potassium levels.