Megalis-D Tablet
By MACLEODS PHARMACEUTICALS
4 Tablet(s) in Strip
₹251.19
✱
₹364.04
31% OFF
₹62.8/tablet
(Inclusive of all taxes)
✱
Offer applicable on order above ₹100015 days return policyRead More
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Description
Megalis D tablet is a medication for treating erectile dysfunction and premature ejaculation in adult men. It contains a combination of two active ingredients: tadalafil and dapoxetine. Tadalafil is a PDE5 inhibitor that works by relaxing the smooth muscles and improving blood flow to the penis, which helps achieve and maintain an erection. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of serotonin in the nervous system. This action helps to increase the time it takes to ejaculate and improves control over ejaculation, providing a calming effect and reducing anxiety.
Megalis D tablet is only for men. It should be taken as advised by your doctor, usually a couple of hours before sexual intercourse. It is crucial not to take it more than once a day. The medicine does not cause dependency or severe withdrawal symptoms, but it is important to follow your doctor's instructions. Do not use this medication without a proper medical diagnosis.
You should not use Megalis D if you have low blood pressure, bleeding disorders, a history of heart conditions, or severe kidney or liver disease. It is contraindicated if you are under 18 years old, have been diagnosed with mania or bipolar disorder, or are using certain recreational or antidepressant medicines.
The medicine should be used with caution, and you should let your doctor know about any other medications, including herbal remedies or supplements, you are taking. This is to prevent potential severe interactions. For example, it can have dangerous interactions with certain antidepressants and medicines that affect heart rhythm.
Product Summary
| Offer Price | ₹251.19 |
| You Save | ₹112.85 (31% on MRP) |
| Contains | Tadalafil(10.0 Mg)+Dapoxetine(30.0 Mg) |
| Therapy | SEXUAL WELLNESS |
Uses
Megalis D tablet is used for treating erectile dysfunction and premature ejaculation in adult men.
Contraindications
- If you are allergic to any active substances or ingredients of the medicine
- If you have not been appropriately diagnosed with premature ejaculation or erectile dysfunction
- If you have low blood pressure (may cause orthostatic hypotension – a drop in blood pressure after suddenly changing positions)
- If you are younger than 18 years of age
- If you have bleeding disorders (this medicine may increase the risk of bleeding)
- If you have a seizure condition
- If you have been diagnosed with mania or bipolar disorder
- If you have been using any recreational drugs
- If you are using any antidepressant medication
- If you have a history of heart conditions, such as heart failure or heart rhythm disorders
- If you have serious kidney or liver disease
Side effects
- Drowsiness
- Nausea
- Vomiting
- Back pain
- Muscle pain
- Flushing
- Stuffy nose
- Dizziness
- Decreased libido
- Headache
- Increased sweating
- Low blood pressure
Precautions and Warnings
Driving
Q:
Can I drive if I have taken the Megalis D tablet?
A:
No, the Megalis D tablet can impair your driving ability. It can have adverse effects like dizziness, confusion, blurry vision, drowsiness, and concentration problems, making driving difficult and unsafe.
Alcohol
Q:
Can I consume alcohol with the Megalis D tablet?
A:
No, it is not safe to consume the Megalis D tablet with alcohol. It can interfere with the functioning of this medicine and cause increased side effects like drowsiness, tremors, dizziness.
Other General Warnings
Talk to your doctor if
- You have not been diagnosed with erectile dysfunction or premature ejaculation by a doctor. Do not self-medicate.
- You are under 18 years old and not suitable for children.
- You have been diagnosed with hypotension or low blood pressure; this medicine can cause a sudden drop in blood pressure.
- If you are over 65 years old, consult your doctor before taking this medicine.
- If you are using any ayurvedic, herbal medicines, or supplements for premature ejaculation or erectile dysfunction, notify your doctor to avoid potential side effects.
- You have any deformity or other conditions affecting the penis.
- You have been diagnosed with sickle cell anaemia, blood or bone marrow cancers, or other conditions that increase the risk of prolonged erection; inform your doctor.
- You have severe kidney or liver conditions.
- You experience any vision or hearing loss, immediately notify your doctor.
Directions for Use
- Use the Megalis D tablet precisely as directed by your doctor.
- Do not exceed the dosage.
- Do not crush, break, or chew the tablet.
- You must swallow the medicine whole, with a glass of water, immediately after opening the bottle.
- This medicine can be taken with or without food.
- You must take the tablet one hour before sexual intercourse or as advised by your doctor.
Storage and disposal
- Store the Megalis D tablets at room temperature in a dry, airtight container. This medicine should not be exposed to heat or wet surfaces. Keep it away from the reach of children and pets.
- Carefully dispose of unused or expired medicine. Do not use the medicine if the package is already broken before using.
Quick Tips
- Take the Megalis D tablet exactly as directed by your doctor.
- Do not crush, break, or chew the tablet; swallow it whole with a glass of water.
- The medicine can be taken with or without food.
- Take the tablet one hour before sexual intercourse or as your doctor advises.
- Do not exceed the prescribed dosage or take the tablet more than once a day.
- Do not consume alcohol while on this medication, as it can increase side effects.
- Avoid driving or operating heavy machinery as the medicine can cause dizziness and drowsiness.
- Inform your doctor if you are taking any other medicines, especially nitrates, antifungals, or antidepressants.
- Store the tablets at room temperature in a dry, airtight container, and keep them out of reach of children.
Dosage
Overdose
The Megalis D tablet overdose can cause adverse reactions such as gastrointestinal disturbances like nausea and vomiting, prolonged erection, low blood pressure, chest pain, increased heart rate, dry mouth, nose bleeds, indigestion, flushing, agitation, and dizziness. In cases of overdose, consult your doctor and seek medical treatment....
Missed a Dose
The dose and duration of the Megalis D tablet are not fixed. Missing a dose is highly unlikely if you are using these tablets for erectile dysfunction and premature ejaculation, as it is used when required or suggested by the doctor....
Mode of Action
How Does It Work?
Megalis D tablet contains two active ingredients: tadalafil and dapoxetine. Tadalafil inhibits certain enzymes like PDE5. It results in causing smooth muscles to relax and improve blood flow into the penis. It increases erectile ability. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) medicine. It works by increasing serotonin levels in the nervous system, a neurotransmitter in the body. It results in an increase in the time it takes to ejaculate, and it also improves control over ejaculation. It is also responsible for reducing anxiety and frustration and producing a calming effect....
Interactions
Interactions with other medicines
- If you use the Megalis D tablet and certain antidepressants (MAO inhibitors), it can cause severe and fatal interactions.
- If you are using medicines that affect the heart rhythm, such as thioridazine, Megalis D tablet can worsen their effects and cause heart rhythm problems.
- If you are using any antipsychotic medicines, sleeping medication, opioid pain relievers, anti-seizure medicines, it can increase the effects of drowsiness, etc.
- Do not use Megalis D tablet if you are using nitrates and medication for pulmonary hypertension.
- Megalis D tablet can also interact with the effects of antibiotics, antifungals, anti-TB medicines, anti-anginal medicines, HIV medication, etc.
Interactions with food items
Avoid consuming grapefruit or its juice, as it can increase the levels of Megalis D tablet medicine in the body. Do not take St. John’s wort, a herbal product that aids in the treatment of depression, with this medication....
Content Details
WRITTEN BY
Ravindra Ghongade
B. Pharm
REVIEWED BY
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Can I stop using the Megalis D tablet whenever I want?
A: The Megalis D tablet should be only used when required or exactly in the way your doctor prescribed. This medicine will help you control ejaculation and cause an erection while using it. If you stop it suddenly, these conditions might return. Consult your doctor if you wish to discontinue use.
Q: Can I have any side effects if I suddenly stop using the Megalis D tablet?
A: Do not stop taking this medicine without informing your doctor. But, if you stop using the Megalis D tablet, it does not cause any serious side effects. However, erectile dysfunction or premature ejaculation can return without this medicine. Consult your doctor if you want to stop using it.
References
View All
- The safety of Dapoxetine/Tadalafil combination therapy - full text view [Internet]. Full Text View - ClinicalTrials.gov. 2025 [cited 24th September 2025]
- Dresser MJ, Desai D, Gidwani S, Seftel AD, Modi NB. Dapoxetine, a novel treatment for premature ejaculation, does not have pharmacokinetic interactions with phosphodiesterase-5 inhibitors. [Internet]. International journal of impotence research. U.S. National Library of Medicine; 2025 [cited 24th September 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 24th September 2025]
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Product Details
Brand
MEGALIS
Country of Origin
India
Expiry Date
29/04/2027
Manufacturer Details
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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