Leupo 11.25mg Dry Vial Of 1 Powder For Injection
Description
Leupo Powder For Injection contains leuprorelin (leuprolide), a synthetic GnRH analogue that suppresses testosterone in men and estrogen in women after continuous administration. It is used for prost
ate cancer, uterine fibroids, endometriosis, and central precocious puberty in children. By lowering sex hormone levels, it helps control hormone-dependent disease progression and related symptoms such as pelvic pain, heavy menstrual bleeding, or early sexual development. Leupo Powder For Injection is administered by a healthcare professional and should not be self-administered. It must not be used in patients allergic to leuprorelin or other GnRH analogues such as goserelin or triptorelin, during pregnancy or breastfeeding, or in women with unexplained vaginal bleeding. Inform your doctor if you have diabetes, heart disease, osteoporosis risk factors, liver problems, urinary obstruction, or a history of seizures. Initial treatment may temporarily worsen symptoms due to hormone flare. Long-term use may cause bone thinning. Blood sugar, lipids, liver function, and heart rhythm may change. Common side effects include hot flushes, headache, mood changes, joint pain, decreased libido, nausea, fatigue, and injection site reactions.
Product Summary
| Offer Price | ₹9055.55 |
| You Save | ₹2127.45 (19% on MRP) |
| Contains | Leuprolide / Leuprorelin(11.25 Mg) |
| Uses | Prostate cancer in men, uterine fibroids and endometriosis in women and early puberty in children |
| Side effects | Headache, nausea, fatigue, weight changes, hot flushes |
| Therapy | DRUGS FOR UTERINE FIBROIDS, ANTI-NEOPLASTIC, DRUGS FOR ENDOMETRIOSIS, DRUGS FOR FEMALE INFERTILITY |
Uses
- Leupo Powder For Injection is used in men for the treatment of prostate cancer. It lowers testosterone levels, which helps slow the growth of cancer cells that depend on this hormone.
- In pre and perimenopausal women, it is used for hormone-responsive early and advanced breast cancer. It may also be prescribed to preserve ovarian function during chemotherapy.
- It is used in women to treat endometriosis and uterine fibroids, which may cause pelvic pain, heavy menstrual bleeding, and pressure symptoms. It can also reduce the thickness of the uterine lining before surgery....
- In children, it is indicated for central precocious puberty. It helps delay early sexual development by suppressing premature hormone release from the pituitary gland.
Contraindications
- If you are allergic to leuprorelin or any of the components of this medicine.
- If you are allergic to similar GnRH analogues such as goserelin or triptorelin.
- If you are pregnant or planning pregnancy.
- If you are breastfeeding.
- If you have abnormal vaginal bleeding that has not been discussed with your doctor.
- If the girl being treated for central precocious puberty is pregnant or breastfeeding.
Side effects
- Hot flushes
- Sweating
- Headache
- Mood changes
- Depression
- Difficulty sleeping
- Bone pain
- Joint pain
- Muscle weakness
- Vaginal dryness
- Vaginal bleeding
- Decreased libido
- Erectile dysfunction
- Weight changes
- Injection site reactions
- Nausea
- Dizziness
- Fatigue
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have diabetes, as blood glucose levels may change during treatment and require monitoring.
- You have heart problems or arrhythmia, as the risk of heart rhythm disturbances may increase.
- You have risk factors for osteoporosis, as bone thinning may occur during prolonged therapy.
- You develop a depressed mood or have a history of depression, as symptoms may worsen.
- You or your child have a history of seizures, as seizure episodes have been reported.
- You experience severe headache, visual disturbances, or ringing in the ears, as this may indicate increased intracranial pressure.
- You have fatty liver, as monitoring of liver function may be required.
- You have spinal cord compression or urinary obstruction due to prostate cancer, as symptoms may initially worsen.
- You are taking medicines that affect heart rhythm such as quinidine, amiodarone, or sotalol, as QT prolongation risk may increase.
Mode of Action
How Does It Work?
Directions for Use
- Leupo Powder For Injection should be administered by a doctor or nurse. It is given as a subcutaneous injection in the arm, thigh, or abdomen. The injection site should be rotated regularly.
- It is usually given once every month. In specific conditions such as endometriosis or uterine fibroids, treatment duration may be limited as advised by the doctor. In children, dosing depends on body weight and is adjusted individually....
Interactions
Interactions with other medicines
- Leuprorelin may interact with:
- Antiarrhythmic medicines such as quinidine, procainamide, amiodarone, and sotalol, which may increase risk of QT prolongation.
- Methadone, moxifloxacin, and antipsychotics, which may increase risk of heart rhythm disturbances.
- Antidiabetics, as blood glucose control may be affected.
- Monitoring may be required during combined use.
Storage and disposal
- Do not store above 25°C. Do not refrigerate or freeze. Store in the original container to protect from light. Use immediately after mixing with the sterile solvent.
- Do not use after the expiry date. Dispose of unused medicine as advised by your pharmacist.
Dosage
Overdose
Missed a Dose
Content Details
Dr. Mansi Savla
B. Pharm, PharmD
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is the use of Leupo Powder For Injection?
- Leupo Powder For Injection is used in men for the treatment of prostate cancer.
- It is also used in women to treat uterine fibroids and endometriosis (causing symptoms such as menstrual cramps, excessive bleeding, pain while urinating, etc.).
- This medicine is also used in children to treat early puberty.
Q: What should be discussed with my healthcare professional before I start the treatment with Leupo Powder For Injection?
- Inform the doctor about your detailed medical & surgical history.
- Inform your doctor if you have heart, liver or kidney disease or have fits.
- Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.
- Leupo Powder For Injection may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also, inform your doctor if you are stopping any medicine....
Q: Does Leupo need to be refrigerated?
- Store Leupo under the conditions mentioned on the pack.
- It is usually stored at room temperature, protected from moisture.
- Keep it out of reach of children and pets.
Q: How do you take Leupo Powder For Injection?
- Leupo Powder For Injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
References
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