Grafyrec 900 Iu Injection 1 Ml

• Grafyrec Injection is used to manage specific reproductive health conditions in women.

• Known hypersensitivity to recombinant FSH products or any component of Grafyrec Injection (reactions have included anaphylaxis).
• High FSH levels indicating primary ovarian or testicular failure.
• Uncontrolled non-gonadal endocrine disorders (for example, thyroid, adrenal, or pituitary disorders).
• Sex hormone-dependent tumors of the reproductive tract or accessory organs.
• Tumors of the pituitary gland or hypothalamus.
• Abnormal uterine bleeding of unknown cause.
• Ovarian cyst or enlargement of unknown cause.

• Ovarian cyst
• Headache
• Abdominal pain
• Ovarian hyperstimulation
• Nausea
• Flatulence (gas)
• Pain
• Intermenstrual (between-period) bleeding
• Pelvic pain

Other General Warnings

• You have, or have had, ovarian cysts, ovarian torsion, polycystic ovarian disease, or abnormal vaginal bleeding of unknown cause (women).
• You have a personal or family history of blood clots, or other risk factors for blood clots such as severe obesity.
• You have asthma or a history of lung problems.
• You have had stomach (abdominal) surgery.
• You have thyroid, adrenal, or pituitary problems that are not well controlled.
• You have had a tumor of the reproductive organs, breast, pituitary gland, or hypothalamus.
• You are pregnant, think you may be pregnant, or are breastfeeding.

• Grafyrec Injection is given as an injection under the skin only, by a trained healthcare provider, exactly as prescribed by your doctor.
• At times, your doctor might ask you to self-administer the medicine at home, but this should be done only after proper training from a healthcare provider.
• Do not change the dose or schedule unless your healthcare provider tells you to. Change the injection site as shown by your healthcare provider to reduce discomfort.
• Never attempt to change, delay, skip, or repeat a dose on your own.

• Before first use, unopened vials of Grafyrec Injection are stored either in the refrigerator, between 36°F and 46°F (2°C to 8°C), or at room temperature, between 68°F and 77°F (20°C to 25°C), until the expiry date, protected from light.
• Grafyrec Injection and all medicines are kept out of the reach of children.

• Follow your monitoring schedule closely, including blood tests, urine tests, and ultrasound scans, as this therapy requires close supervision.
• Report severe pelvic pain, sudden weight gain, nausea, vomiting, diarrhea, or reduced urination immediately to your doctor, as these may be signs of OHSS.
• If you develop symptoms like one-sided abdominal pain, or shoulder, neck, or rectal pain together with nausea, inform your doctor immediately, as this may signal an ectopic pregnancy.
• Talk with your partner about the possibility of a multiple pregnancy before starting therapy.
• Do not change your dose or injection schedule unless your healthcare provider tells you to. Change your injection site each time, as shown by your healthcare provider.

Overdose

Missed a Dose

Interactions with other medicines

• Patients should tell their doctor about all prescription medicines, over-the-counter medicines, supplements, and herbal products they are taking before and during Grafyrec Injection treatment.