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Domadol 50mg Injection 1ml

1ml Injection in Ampoule
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Domadol 50 MG Description

Domadol is a prescription medication available in injectable form. The active ingredient of Domadol is Tramadol 50 mg. Tramadol is used to manage severe pain, which is an uncomfortable sensation

that occurs due to the release of certain chemical substances relayed to the brain. It indicates tissue damage in the form of an injury. It can vary in severity from mild to very severe. Directions for use of Domadol should be strictly followed. The medicine should be administered as an injection by a trained healthcare professional, following the guidance of a medical doctor. It should never be self-administered. This medication is not recommended for use for more than five days in the management of acute pain. Long-term use of Domadol can be addictive and can be misused. Side effects of Domadol include nausea, dizziness, constipation, vomiting, and confusion. It is essential to inform the doctor of any underlying medical conditions and use of any other medications at the time of prescription of Domadol. Pregnant or breastfeeding women also need to inform the doctor.


Product Summary

Offer Price₹9.74
You Save₹1.72 (15% on MRP)
ContainsTramadol(50.0 Mg)
UsesTreatment of severe pain
Side effectsNausea, Constipation, Dizziness, Sleepiness, Dry mouth, Confusion, Vomiting
Check more medicines with composition as Tramadol(50.0 Mg)

Uses of Domadol 50 MG

  • As per CDSCO, Domadol is used in:
  • Treatment of severe acute and chronic pain
  • Management of procedural and post-surgical pain

Contraindications of Domadol 50 MG

  • Domadol injection should not be administered or be given with caution:
  • If you are hypersensitive to any of the components of this injection.
  • If you have a known or suspected intestinal obstruction, including paralytic ileus.
  • If you use this medication concomitantly with alcohol; this can be life-threatening and result in respiratory depression, coma and even death.
  • If you have any seizure disorders, especially those not adequately controlled with medications; Domadol is contraindicated in such cases.
  • If you are under 12; this injection is contraindicated in children.
  • If you are under 18 and have undergone tonsillectomy and/or adenoidectomy; this injection is contraindicated in post-operative management.
  • If you have severe/acute bronchial asthma in an unmonitored setting or the absence of resuscitative equipment.
  • If you have significant respiratory depression.
  • If you have severe liver or kidney disease.
  • If you are in labour; this injection is not meant for use during childbirth.
  • If you have a head injury; this injection is not meant for pain relief in such cases.

Side effects of Domadol 50 MG

  • Domadol injection can cause side effects such as:
  • Nausea
  • Dizziness
  • Constipation
  • Vomiting
  • Confusion
  • Dry mouth
  • Sleepiness (somnolence)

Precautions and Warnings of Domadol 50 MG



Can I take Domadol during pregnancy?
This medication is unsafe during pregnancy. It is a category C medication. Inform your doctor regarding your pregnancy or intention to conceive at the time of prescription of Domadol.

Breast Feeding

Can I take Domadol while breastfeeding?
This medication is unsafe during breastfeeding. Inform your doctor if you are breastfeeding at the time of prescription of Domadol.


Can I drive if I have taken a Domadol injection?
This medication can cause drowsiness, dizziness, and sleepiness. Driving or operating heavy machinery is not advisable when using this medication.


Can I consume alcohol with Domadol?
Mixing alcohol with this medicine can lead to severe effects on the brain, causing respiratory depression, coma, and even death. It is strongly contraindicated.

Other General Warnings

Talk to your doctor if
  • You take other medications for your existing conditions; tramadol in this injection interacts with many other medications that use the same metabolic enzymes.
  • You have liver or kidney issues.
  • You have a history of substance use/misuse.

Mode of Action of Domadol 50 MG

How Does It Work?

Tramadol is an opioid that acts on specific receptors in the brain to produce effects to decrease pain, otherwise known as analgesia. Certain chemical messengers in the brain, called neurotransmitters...
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Directions for Use of Domadol 50 MG

  • Domadol injection should be used as directed by your treating physician.
  • It should be strictly administered by a trained healthcare professional, like a doctor or a nurse.
  • Do not self-administer this medication.
  • This medication should not be administered outside of a healthcare facility setting.
  • Do not use it if the solution is unclear or has any suspended matter.

Interactions of Domadol 50 MG

Interactions with other medicines

  • Concurrent use of monoamine oxidase inhibitors (MAOIs) like selegiline and rasagiline or their use within the last 14 days is contraindicated.
  • This medicine can cause serotonin syndrome when used with other medicines that increase the level of serotonin in the brain; this condition is potentially life-threatening. Serotonergic medicines incl...
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  • It should not be used with other medications that are known to decrease the seizure threshold.
  • This injection should not be used with medications like warfarin that prevent blood clotting.
  • Domadol injection should not be mixed with benzodiazepines or other CNS depressants, including alcohol, as it may result in profound sedation, respiratory depression, coma, and even death.
  • Always inform your doctor about your medications to prevent unwanted interactions.

Storage and disposal of Domadol 50 MG

Store Domadol injection in its original container. Store the vial at room temperature, away from excess heat and humidity at 20 to 25℃. Keep this injection away from the reach of kids and pets. Do not...
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Dosage of Domadol 50 MG


Overdose with this medication can cause severe respiratory depression, coma, flaccidity of muscles, cold, clammy skin, fall in heart rate and blood pressure, and even death. It can cause severe liver ...
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Missed a Dose

If you miss a dose of Domadol injection, consult your treating doctor. Do not double the dose of the medication. Do not self-administer this medication in the absence of a trained healthcare professio...
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Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I was given a Domadol injection for pain. Since then, I have been experiencing continuous pain at the site of the injection. Do I need to consult a doctor?

A: Pain at the injection site is a common side effect of Domadol injections. The pain will subside on its own. However, if the pain persists, it is advisable to consult a doctor.

Q: I feel better while using this medication and want to continue taking it for managing my pain. Can I take this injection for the long term?

A: Domadol is recommended for the treatment of severe, acute pain for not more than five days. This medication has the potential to develop dependence in users. It should only be administered according to the directions of your treating doctor. Consult your doctor for more information on long-term pain management.

Q: My elderly father has severe pain following an injury. Can this medication be used to manage his pain?

A: This medication should be used very cautiously in older adults above 75, especially if there is any underlying liver or kidney impairment. Consult your treating doctor for their assessment and recommendation of painkillers. Do not use this medication without the guidance of a doctor.
Product Details
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Last Updated on: 04 Mar 2022 | 04:52 PM (IST)
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