Atovastrin Ez F Strip Of 10 Tablets

• If you are allergic to atorvastatin, fenofibrate, ezetimibe, other statins or fibrates, or any of the other ingredients of this medicine.
• If you have active liver disease or persistently raised liver enzymes of unexplained cause.
• If you are pregnant, breastfeeding, or of childbearing age and not using reliable contraception.
• If you have severe kidney impairment.
• If you have gallbladder disease or gallstones.
• If you have had a photoallergic or phototoxic reaction to a fibrate or to ketoprofen.
• If you have chronic or acute pancreatitis not caused by raised triglycerides.

• Muscle aches
• Headache
• Abdominal pain
• Nausea
• Diarrhoea
• Wind
• Constipation
• Raised liver enzymes
• Tiredness
• Dizziness

Other General Warnings

• You have kidney disease or reduced kidney function
• You have liver disease or a history of liver problems
• You have unexplained muscle pain, tenderness, weakness, or cramps
• You have a history of muscle disorders or muscle injury related to medicines
• You have diabetes or are at risk of developing diabetes
• You have an underactive thyroid (hypothyroidism)
• You have gallbladder disease or a history of gallstones
• You have had a recent stroke or any serious cardiovascular event
• You have persistent fatigue, loss of appetite, or yellowing of the skin or eyes
• You have dark-colored urine or severe muscle pain with fever
• You have allergy symptoms such as swelling of the face, lips, tongue, or throat
• You have a fever or skin rash after taking this medicine
• You are elderly or have any long-term medical condition
• You are taking other cholesterol-lowering medicines, blood thinners, or immunosuppressants

• Take Atovastrin Ez F tablet as directed by your doctor.
• Swallow the tablet whole with a glass of water and do not crush or chew it.
• Take it at the same time each day, with or without food, though taking it with a meal may reduce stomach upset.
• Continue the low-fat diet and exercise plan your doctor has advised, as this medicine works alongside them.
• Keep taking it long term, as your blood fats will rise again if you stop.

• Store Atovastrin Ez F tablet in a cool and dry place, protected from direct sunlight, moisture and heat.
• Keep it in the original packaging until you take it.
• Keep the medicine out of the reach of children and pets.
• Do not use it after the expiry date or if it looks damaged.
• Do not flush unused medicine down the toilet or throw it into a drain. Return it to a pharmacy for safe disposal.

• Take Atovastrin Ez F tablet at the same time each day and continue it long term, as your blood fats will rise again if you stop.
• Tell your doctor promptly about unexplained muscle pain, tenderness, weakness or cramps, particularly with fever or dark urine. The statin and fibrate together raise this risk.
• Keep to the low-fat diet and exercise plan, as these have a direct effect on triglycerides.
• Limit alcohol, which raises triglycerides and adds to liver and pancreas risk.
• Avoid large amounts of grapefruit and grapefruit juice.
• Report severe upper abdominal pain spreading to the back, as the fenofibrate component can rarely inflame the pancreas or form gallstones.
• Keep your blood fat, liver function, kidney function and muscle enzyme tests as arranged.
• Tell your doctor immediately if you become pregnant or are planning to.

Overdose

Missed a Dose

Interactions with other medicines

• Tell your doctor about all the medicines, supplements and herbal products you use before starting Atovastrin Ez F tablet, and before any surgery.
• Ciclosporin, clarithromycin, erythromycin, itraconazole, ketoconazole and some HIV medicines raise the level of atorvastatin and markedly increase the risk of muscle damage.
• Gemfibrozil must not be combined with this medicine, as the risk of serious muscle injury is too high.
• Taking a statin and a fibrate together, as in this medicine, already carries a higher risk of muscle problems, so report muscle symptoms promptly.
• This medicine increases the effect of blood thinners such as warfarin, so your clotting tests will need checking more often.
• Colestyramine and antacids reduce how much ezetimibe is absorbed, so space them apart from your dose.
• Rifampicin and St John's wort can lower the level of atorvastatin and make it less effective.
• Nicotinic acid, colchicine and some antifungals add further to the risk of muscle side effects.

Interactions with food items