Atorvastatin+Fenofibrate+Ezetimibe
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Molecule Summary
| Uses | High cholesterol and high triglycerides |
| Therapy | Hypolipidemic Drugs |
| Side Effects | Nausea, stomach pain, constipation, gas, headache |
Medicines
available
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Molecule Description
Atorvastatin+Fenofibrate+Ezetimibe is a fixed-dose combination medicine used to manage high cholesterol and triglyceride levels in the blood. It is used along with a low-fat diet and healthy lifestyle changes in patients who require better lipid control. By lowering bad cholesterol (LDL) and triglycerides, this medicine helps reduce the risk of heart disease, stroke, and other cardiovascular complications.
It works through the combined action of its active ingredients. Atorvastatin reduces the production of cholesterol in the liver, ezetimibe decreases the absorption of cholesterol from the intestine, and fenofibrate helps in the breakdown and removal of triglycerides from the blood. Together, these mechanisms provide comprehensive lipid control and improve overall cholesterol balance.
Atorvastatin+Fenofibrate+Ezetimibe should be taken exactly as prescribed by the doctor. The medicine should be taken with a sufficient amount of water, with or without food, preferably at the same time each day. Do not crush, chew, or break the medicine, and do not take more than the recommended dose, as this may increase the risk of side effects.
Some common side effects of using Atorvastatin+Fenofibrate+Ezetimibe include headache, nausea, indigestion, constipation or loose motions, stomach or back pain, muscle or joint pain, and fatigue. These effects are usually mild and resolve with time. However, consult your doctor immediately if you experience severe muscle pain, weakness, unusual tiredness, or other symptoms.
Uses
Atorvastatin+Fenofibrate+Ezetimibe is used to:
Contraindications
When should one not use Atorvastatin+Fenofibrate+Ezetimibe
- If you are allergic to atorvastatin, ezetimibe, fenofibrate, or any other ingredient of Atorvastatin+Fenofibrate+Ezetimibe
- If you have active or severe liver disease or persistently increased liver enzymes
- If you have severe kidney disease
- If you have gallbladder disease or a history of gallstones
- If you are pregnant or planning to become pregnant
- If you are breastfeeding or planning to breastfeed
- If you have a history of muscle disorders related to cholesterol-lowering medicines
- If you are taking medicines that may significantly increase the risk of serious muscle or liver problems, unless advised by your doctor
Side effects
Common side effects of this drug are:
Common side effects may include:
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have kidney disease or reduced kidney function
- You have liver disease or a history of liver problems
- You have unexplained muscle pain, tenderness, weakness, or cramps
- You have a history of muscle disorders or muscle injury related to medicines
- You have diabetes or are at risk of developing diabetes
- You have an underactive thyroid (hypothyroidism)
- You have gallbladder disease or a history of gallstones
- You have had a recent stroke or any serious cardiovascular event
- You have persistent fatigue, loss of appetite, or yellowing of the skin or eyes
- You have dark-colored urine or severe muscle pain with fever
- You have allergy symptoms such as swelling of the face, lips, tongue, or throat
- You have a fever or skin rash after taking this medicine
- You are elderly or have any long-term medical condition
- You are taking other cholesterol-lowering medicines, blood thinners, or immunosuppressants
Mode of Action
How Does It Work?
- Atorvastatin lowers cholesterol production in the liver
- Ezetimibe reduces cholesterol absorption from food
- Fenofibrate helps break down triglycerides
- This combined action improves lipid control and lowers cardiovascular risk.
Dosage
Overdose
Symptoms may include severe muscle pain or breathing difficulty. In case of overdose, seek immediate medical attention.
Missed a Dose
- Take the missed dose as soon as you remember
- Skip it if it is almost time for the next dose
- Do not double the dose
Frequently Asked Questions (FAQs)
Articles
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References:
- Zetia (ezetimibe) prescribing information [FDA label]. U.S. Food and Drug Administration. 2023. [cited 2026 Jun 3].
- Tricor (fenofibrate) tablet prescribing information [FDA label]. U.S. Food and Drug Administration. 2019. [cited 2026 Jun 3].
- Atorvastatin prescribing information [FDA label]. U.S. Food and Drug Administration. 2026. [cited 2026 Jun 3].
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