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Voglibose+Metformin Hydrochloride

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Molecule Summary

Uses
Type 2 diabetes mellitus
Therapy
Anti-Diabetic
Side Effects
Nausea, vomiting, diarrhoea, stomach pain, constipation, taste disturbance, loss of appetite
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Molecule Description

Voglibose+Metformin Hydrochloride is used to treat type 2 diabetes. It is a combination of metformin and voglibose, which helps lower elevated blood sugar levels. It is important to take this medication as prescribed by your doctor for the specified duration. Voglibose+Metformin Hydrochloride should ideally be taken with food to help prevent nausea and abdominal discomfort. To maximize its effectiveness, take it consistently at the same time each day. Do not stop using the medication unless your doctor advises you to do so. Common side effects of Voglibose+Metformin Hydrochloride may include diarrhoea, nausea, vomiting, gas, weakness, indigestion, abdominal pain, headaches, and decreased appetite. Some individuals might also experience hypoglycemia (low blood sugar) when taking this medication in combination with other antidiabetic drugs, consuming alcohol, or missing meals. Be sure to monitor your blood sugar levels regularly while taking this medication. Before starting this medication, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Please ensure that you discuss all medications and supplements you are currently taking, as well as any existing health conditions or illnesses you may have. Managing diabetes is heavily affected by your lifestyle; therefore, it is vital to follow the diet and exercise plan recommended by your healthcare provider while using this medication.

Uses

Voglibose+Metformin Hydrochloride is used for type 2 diabetes mellitus when diet and exercise have not been able to control your blood glucose levels and to improve post-meal blood glucose levels with diet and exercise.

Contraindications

When should one not use Voglibose+Metformin Hydrochloride

  • If you are allergic to metformin, voglibose or any other ingredients of Voglibose+Metformin Hydrochloride.
  • If you have severe problems with your liver or kidneys.
  • If you are an alcoholic (you daily consume alcohol in excess).
  • If you have uncontrolled diabetes.
  • If you have any heart problems or if you have recently had a heart attack.
  • If you have a severe infection of the lung or kidney. Infections can increase the risk of lactic acidosis.
  • If you have a severe infection or are undergoing surgery.
  • If you recently had severe trauma or injury.
  • If you have a blockage in any part of your digestive system.

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Taste disturbance
  • Loss of appetite

Precautions and Warnings

Pregnancy

Pregnancy

Consult your doctor before taking Voglibose+Metformin Hydrochloride during pregnancy, as limited information is available about its safety in pregnant women.

Breast Feeding

Breast Feeding

Voglibose+Metformin Hydrochloride is known to pass into breast milk. However, the amount is significantly low to cause any side effects. So, Voglibose+Metformin Hydrochloride could be taken by a breastfeeding mother only if prescribed by her doctor.

Driving

Driving

If you are taking Voglibose+Metformin Hydrochloride along with other antidiabetic medications, there is a chance that your blood sugar may drop. You may experience dizziness, increased sweating, weakness, and difficulty concentrating, which can impair your ability to drive safely. Therefore, you should exercise extra caution when driving. Always keep sugar, juice or a bar of chocolate in your car while driving. If you experience any of the symptoms, stop driving immediately and have sugar or juice. Do not consume sugar-free items during such episodes.

Alcohol

Alcohol

Avoid excessive consumption of alcohol while taking Voglibose+Metformin Hydrochloride. Alcohol lowers blood sugar, which can be dangerous, and also increases the risk of a serious condition called lactic acidosis.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are suffering from continuous diarrhoea, vomiting, and loss of body fluids.
  • You experience signs of low blood glucose, such as dizziness, weakness, a rapid heartbeat, sweating, and difficulty concentrating. Metformin does not usually cause sudden low blood sugar (hypoglycemia). If Voglibose+Metformin Hydrochloride is prescribed with other anti-diabetic medications, low blood sugar may occur.
  • You experience muscle pain, stomach pain, vomiting, breathing difficulty, and low body temperature. This could be a serious condition known as lactic acidosis.
  • You have severe vomiting or diarrhoea. Your doctor may ask you to stop taking Voglibose+Metformin Hydrochloride for a short time.
  • You are stressed, have an injury, or an infection, as it can lead to loss of blood sugar control.

Mode of Action

How Does It Work?

  • Metformin works by reducing glucose production in the liver, slowing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin.
  • Voglibose works by delaying the digestion and absorption of carbohydrates in the intestine, thereby preventing a spike in blood glucose levels that occurs after a meal.

Interactions

Interactions with other medicines

  • Voglibose+Metformin Hydrochloride may interact with other medicines. Discuss all the medicines, supplements, or herbal preparations you are taking with your doctor. Additionally, please inform your doctor if you have a planned surgery or vaccination scheduled.
  • Medicines used to reduce pain and swelling, such as ibuprofen and celecoxib.
  • Medicines used to treat asthma, such as salbutamol or terbutaline.
  • Medicines like furosemide (diuretics).
  • If you need to receive an injection of iodine-containing contrast medium into your bloodstream for an X-ray or scan, your doctor will ask you to stop taking Voglibose+Metformin Hydrochloride before or at the time of the procedure.
  • If you are on medicines that are used to treat pain and inflammation (NSAIDs and COX-2 inhibitors, such as ibuprofen and celecoxib) for the long term, these can damage your kidneys. The use of such medicines in diabetes should be avoided.

Interactions with food items

  • The absorption of vitamin B12 appears to be reduced during long-term Voglibose+Metformin Hydrochloride therapy, and annual screening of serum vitamin B12 levels and red blood cell parameters is recommended.
  • It is advisable to have a diabetic diet as advised by your doctor or dietician. This medicine works best along with a good diet and exercise. Exercise is known to decrease insulin resistance.

Dosage

Overdose

An excess of Voglibose+Metformin Hydrochloride may lead to lactic acidosis, causing symptoms such as vomiting, stomachache, muscle cramps, and difficulty breathing. You must seek immediate emergency medical care if you suspect an overdose.

Missed a Dose

If you miss any dose of Voglibose+Metformin Hydrochloride, take it as soon as you remember with food. However, if it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Frequently Asked Questions (FAQs)

You can take Voglibose+Metformin Hydrochloride at any time of the day, as advised by the doctor. However, it's best to take this medicine with a meal to minimise side effects.

A diet should be high in fibre, low in fat, with adequate protein, carbohydrates, vitamins and minerals. A diet should include boiled, steamed, or baked foods. Ensure moderate use of edible oils (groundnut oil, olive oil). Maintain regular meal times and try to have 2-3 healthy snacks between meals, such as soups and salads.

No, you should never stop taking Voglibose+Metformin Hydrochloride without consulting the doctor. Abruptly stopping the medicine results in a sudden rise in blood glucose levels and causes further harm to the kidneys and other organs.

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