Ursodeoxycholic Acid / Ursodiol
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Molecule Summary
| Uses | Gallstones, liver disorders |
| Therapy | Drugs For Cholelithiasis |
| Side Effects | Diarrhoea, sticky stool, abdominal pain, rashes |
Assurance
available
Regulated
Molecule Description
Ursodeoxycholic Acid / Ursodiol is a bile acid that is naturally produced in the liver. This medication is primarily prescribed for treating liver-related disorders, such as primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and cholesterol-based gallstones. It is also used to manage liver conditions associated with cystic fibrosis. The primary mechanism of action of Ursodeoxycholic Acid / Ursodiol is to reduce the cholesterol content in bile.
Ursodeoxycholic Acid / Ursodiol should be taken after a meal, with a glass of milk or water. The dosage will depend on the condition being treated and your body weight. Take it regularly for maximum benefit, for the duration prescribed (several months or longer), even if symptoms disappear.
Common side effects may include abdominal pain, diarrhoea, hair loss, itching, nausea, and rash. Not everyone experiences these side effects. If you are concerned or if the side effects persist, inform your doctor.
Before taking this medicine, inform your doctor if you have inflammation of the gallbladder or bile ducts, experience frequent cramp-like pain in your upper abdomen, have been coughing up blood, or have gained weight rapidly.
Ursodeoxycholic Acid / Ursodiol may reduce the effectiveness of other medications, so inform your doctor about all other medicines you are taking. Women should stop using hormonal birth control pills, as they can increase the risk of gallstones. Ultrasound scans and regular blood tests may be needed to monitor your liver function during treatment.
Uses
Ursodeoxycholic Acid / Ursodiol is used to treat liver diseases, including primary biliary cirrhosis, gallstones, and liver disease associated with cystic fibrosis.
Contraindications
When should one not use Ursodeoxycholic Acid / Ursodiol
- If you are allergic to ursodeoxycholic acid or any ingredient of this medicine.
- If you are suffering from inflammation/blockage of the gall bladder or biliary tract.
- If you have stomach or intestinal ulcer or bleeding.
- If you have recently had surgery involving any part of your intestine.
- If you have a liver-related disorder and non-functional gall bladder.
- If you are suffering from a liver or intestinal condition which affects the circulation of bile substances like blockage of the bile duct.
Side effects
Common side effects of this drug are:
- Diarrhoea
- Sticky stool
- Abdominal pain
- Rashes
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You experience persistent diarrhoea, and the doctor should discontinue the therapy immediately.
- You have a history of liver disease or obstruction in bile passage, your doctor may ask you to do liver function tests regularly.
- Your doctor may ask you for an ultrasound after six months of the treatment to check the therapeutic improvement.
Mode of Action
How Does It Work?
Ursodeoxycholic Acid / Ursodiol reduces the synthesis and formation of cholesterol and thus reduce the cholesterol content in bile which leads to gradual solubilisation and dissolution of cholesterol gallstones.
Interactions
Interactions with food items
Ursodeoxycholic Acid / Ursodiol should be taken with food to avoid abdominal discomfort or other gastrointestinal side effects.
Dosage
Overdose
The most common symptom of an overdose of Ursodeoxycholic Acid / Ursodiol is diarrhoea. Consult your doctor immediately if you have taken an excessive dose of this medicine.
Missed a Dose
If you have missed taking any dose of this medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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