Tranexamic Acid

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Molecule Description

Tranexamic Acid is a medication used to manage and stop excessive bleeding. It is often prescribed to women who experience heavy menstrual bleeding, also known as menorrhagia, helping to significantly reduce the amount of blood lost during their period. It is a non-hormonal option, making it a good choice for those who want to avoid or can't use hormone-based treatments like certain birth control pills. Tranexamic Acid works by temporarily blocking the enzyme that dissolves these blood clots. By keeping the clot stable for longer, TXA effectively reduces and controls bleeding. It's not just for heavy periods; it's also used in other situations where excessive bleeding needs to be controlled, like nosebleeds or after dental procedures in people with bleeding disorders.

Uses

Tranexamic acid is used to treat heavy bleeding during periods (menstruation). It is also used to treat the blood loss from trauma, surgery, tooth removal and nose bleed.

Contraindications

When should one not use Tranexamic Acid

Allergic reaction due to tranexamic acid
Have blood clot or history of blood clot
Kidney disease
History of fits

Side effects

Common side effects of this drug are:

Back pain
Headache
Joint pain
Rash
Nausea, vomiting, diarrhea
Vision disturbance
Muscle pain
Stomach pain
Tiredness
Dizziness

Precautions and Warnings

Pregnancy

Probably safe during pregnancy. This medicine should be used during pregnancy only if prescribed by your doctor or physician.

Breast Feeding

It passes into breast milk in low quantities and is not recommended during breastfeeding.

Driving

No information is available on the ability to drive or use machines, however, if you observe or experience any side effect, it is advised not to drive or use machines. Contact your doctor or pharmacist for further information.

Alcohol

No information is available on interactions of medicine when taken with alcohol. You may consult your doctor or pharmacist for further information.

Other General Warnings

Talk to your doctor if

You have any medical history, especially of: bleeding in the brain (subarachnoid hemorrhage), history of blood clots (such as in the legs, lung, brain, eye), certain heart diseases (irregular heartbeat, heart valve problems), blood clotting problems, kidney problems (including blood in the urine), irregular menstrual bleeding of unknown cause
On long term use, regular eye check-up should be done

Mode of Action

How Does It Work?

In response to any bleeding in the body, blood clots are formed. This medicine prevents blood clot from breaking too quickly. This helps in controlling excessive bleeding.

Interactions

Interactions with other medicines

This medicine interacts with hormonal birth control pills and this can increase the risk of blood clots.
Anticoagulants like warfarin heparin that may decrease the tranexamic acid effect.

Interactions with food items

There is no food interaction that is reported with tranexamic acid.

Dosage

Overdose

Symptoms of overdose may include severe dizziness and vomiting, low blood pressure, fainting. Seek immediate emergency medical advice in case of an overdose.

Missed a Dose

Take the missed dose as soon as you remember and then take your next dose at least 6 hours later. Do not take a double dose of medicine to make up for a missed one.

Frequently Asked Questions (FAQs)

Use tranexamic acid with caution in children and elderly as they are more sensitive to it.

For heavy periods, you typically take the tablets only when your period has started and you are actively bleeding as directed by your physician. Your doctor will give you specific instructions, but it's generally taken 2-3 times a day for up to 5 days during your menstrual cycle. Do not take it when you are not on your period. Only use it under strict medical supervision.

It is very important to tell your doctor about your medical history, as it is not safe for everyone. You should not take this medicine if you have:A history of blood clots, such as deep vein thrombosis (DVT), pulmonary embolism (PE), or a stroke.Certain serious eye problems related to blood clots.Certain kidney problems (your doctor may adjust the dose).Tell your doctor if you are using a combined hormonal birth control (like the pill, patch, or ring), as taking both can increase the risk of blood clots.

Common side effects may include:Stomach or abdominal pain/discomfortHeadacheMuscle pain or stiffnessBack painTirednessIf you experience signs of a blood clot (such as sudden pain or swelling in your leg, shortness of breath, or sudden change in vision), seek medical help immediately.

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