Tolperisone
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Molecule Description
Tolperisone is used to relieve muscle spasms and related pain. It is a skeletal muscle relaxant that acts centrally on the spinal cord. It works by improving the blood flow towards skeletal muscles and reducing pain. Tolperisone is available in the form of a tablet. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.
Uses
Tolperisone is used for the relief of painful muscle spasms of the skeletal muscles.
Contraindications
When should one not use Tolperisone
- If you are allergic to tolperisone or similar medicines
- If you are breastfeeding
- If you are suffering from an autoimmune disease characterized by muscle weakness (myasthenia gravis)
Side effects
Common side effects of this drug are:
- Drowsiness
- Diarrhea
- Fatigue
- Headache
- Dizziness
- Dry mouth
- Skin rash
- Itching
- Low blood pressure
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have problems with your liver or kidney
- You are on or taking any other medicines
- Tolperisone is not recommended for use in children and adolescents.
Mode of Action
How Does It Work?
Tolperisone acts on the spinal cord and by blocking the exchange of sodium and calcium ions within the cells, thereby relaxing the muscle. Decreased blood supply to various small blood vessels due to muscle contraction can cause trauma to the blood vessels leading to the release of the chemical substance responsible to cause pain. However, tolperisone works by increasing the blood supply to skeletal muscles.
Interactions
Interactions with other medicines
- Some medicines can affect the way tolperisone works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction. Especially if you are taking other muscle relaxants, painkillers
Frequently Asked Questions (FAQs)
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Did you find this helpful?
References:
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 13 December 2021]
- Tolpermyo film-coated tablets [Internet] 2021 [cited 13 December 2021]
- TOLPERISONE-CONTAINING ORAL FORMULATIONS - - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 13 December 2021]
- Assessment report for tolperisone-containing medicinal products (emc) [Internet]. Medicines.org.uk. 2021 [cited 13 December 2021]
- National insitute of pharmacy and nutrition. Merisone [Internet] 2021 [cited 13 December 2021]
- Tolmus [Internet]. Beximcopharma.com. 2021 [cited 13 December 2021]
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