Rizatriptan

Molecule Description

Rizatriptan is primarily used to treat migraine headaches of recent origin. It

belongs to a class of medicines known as ‘Triptans’ or ‘Selective Serotonin Receptor Agonists’ and is available in the form of hard tablets, soft tablets (to be placed under the tongue) or dispersible tablets (to be dissolved in water).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Rizatriptan

Short-term relief in patients with migraine (severe headache) attacks, with or without aura (seeing dazzling or flashing lights).

Contraindications of Rizatriptan

When should one not use Rizatriptan

Allergy to Rizatriptan or any of the ingredients of the medicine
Uncontrolled blood pressure, history of chest pain or heart attacks
Severe liver or kidney problems
Blocked arteries (leading to pain in the legs or heart disease)
Brain stroke (rupture of blood vessels in the brain)
Specific class of antidepressants called Monoamine Oxidase (MAO) inhibitors (Moclobemide, Phenelzine, Tranylcypromine, Paragyline), etc.
Patients using these medicines or an antibiotic called Linezolid can take Rizatriptan only after 14 days after they stopped taking the treatment
Taking other medicines to treat migraine such as ‘Ergot Alkaloids’ or other ‘Triptans’

Side effects of Rizatriptan

Common side effects of this drug are:

Common & Serious:
Decreased sensitivity of skin, tingling, reduced alertness, sleep problems
Irregular or pounding heartbeats
Redness of skin (flushing), throat problems, feeling sick (nausea), vomiting, loose motions, dry mouth, indigestion, stomach or chest pain, heaviness in the body, neck pain and stiffness
Taste disturbances, unable to walk steadily, head spinning, tremors, fainting, blurry vision, confusion, feeling nervous, sweating, high blood pressure, abnormal ECG, tightness in the body, pain in th...
Read more
Severe allergic reaction causing swelling of the face, lips and throat, swallowing and breathing difficulties, with or without itching, rashes, skin peeling and blisters (serious but rare)

Precautions and Warnings of Rizatriptan

Pregnancy

Can I take Rizatriptan during pregnancy?

No evidence is available to confirm that Rizatriptan is harmful when taken during pregnancy — recommended to be used only if other alternatives are not available.

Breast Feeding

Can I take Rizatriptan while breastfeeding?

Rizatriptan is secreted in breast milk. It is advisable not to take this medicine if you are breastfeeding. If other alternatives are unavailable, take care that there is at least a 24-hour gap between taking the tablet and giving breast milk.

Driving

Can I drive if I have consumed Rizatriptan?

Rizatriptan can make you sleepy or dizzy. Driving should be attempted only in the absence of such symptoms.

Alcohol

Can I consume alcohol with Rizatriptan?

Rizatriptan and alcohol cause similar side effects such as feeling sick (nausea), dizziness, headache, dry mouth, etc. and when taken together, these side effects can become severe. Hence, it is advised to avoid alcohol.

Other General Warnings

Talk to your doctor if

High blood pressure, diabetes, smoking, kidney or liver problems, heart rhythm problems
Headache with light-headedness, walking, coordination and balance problems
A certain class of anti-depressants called Selective Serotonin Reuptake Inhibitors (SSRIs) (Sertraline, Escitalopram, Venlafaxine, Duloxetine)
Chest tightness and pain

Mode of Action of Rizatriptan

How Does It Work?

Rizatriptan works by increasing the levels of a useful chemical called ‘serotonin’ whose levels are low in migraine. Low levels of this substance which also transmit signals in the brain (neurotransmi...

Interactions of Rizatriptan

Interactions with other medicines

Avoid specific class of antidepressants called Monoamine Oxidase (MAO) inhibitors (Moclobemide, Phenelzine, Tranylcypromine, Paragyline), etc.
Linezolid (antibiotic)
Other medicines to treat migraine (other Triptans, Ergot derivatives, Methysergide)
You should wait for 14 days in case of MAO inhibitors and Linezolid and 24 hours in case of Ergot derivatives before taking Rizatriptan
Use with caution:
Propanolol (used to treat chest pain or high blood pressure)
A specific class of antidepressants called Selective Serotonin Reuptake Inhibitors (SSRIs) (Sertraline, Escitalopram, Venlafaxine, Duloxetine)
Inform the doctor about all the products you use (including prescription, non-prescription, and herbal medicines, vitamins or diet supplements)

Interactions with food items

Rizatriptan will act slowly if it is taken with food.

Dosage of Rizatriptan

Overdose

Take medication exactly as prescribed. If you are taking higher doses than prescribed, it will lead to severe headaches. Seek medical attention if you experience symptoms of overdose such as feeling d...

If you missed any dose, take it as early as you remember
If it is time for the next dose, skip the missed dose and continue your regular dosing schedule
Do not take a higher or a double dose of medicine to compensate for the missed dose
A minimum gap of 2 hours is required between two dosages and do not take more than two doses in 24 hours

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What causes migraine attacks? Can migraine be cured?

Migraines, in general, are headaches on either side of the head, which may change sides during different attacks. But when they come, the pain is only one side of the head. This headache may be associ...
Read more
Migraine with ‘aura’ is also known as classical migraine. More than 10% of population worldwide suffer from migraine attacks and it is one of the most common neurological disorders
The patterns of headache and triggering factors for migraine differ from patient to patient and cannot be pinpointed. Migraines of different origins and patterns respond to varying types of treatment
The most common reason for migraine is thought to be a highly sensitive brain which reacts to the slightest excitation or irritation, which results in the release of chemicals that irritate the nerves...
Read more
‘Triptans’ or Rizatriptan acts by increasing the levels of Serotonin which regulates the levels of other substances in the brain and normalizes the activity in the brain, thus relieving the pain
There are a total of 7 ‘Triptans’ that are in use to treat migraine headaches – Sumatriptan, Zolmitriptan, Naratriptan, Rizatriptan, Almotriptan, Eletriptan and Frovatriptan
Migraine has no cure but if the triggering factors can be assessed, keeping away from the factors that cause these headaches can keep migraine away

Q: Is Rizatriptan better than other medicines for migraine?

Rizatriptan gives faster relief compared to some other medicines
You can experience significant pain relief within 2 hours of taking this medicine
Overall quality of life is said to be much better with Rizatriptan, and is commonly used by people who go to work
This medicine does not produce the same effect in all patients but is of particular benefit in some kinds of migraines (which are Serotonin dependent)
Rizatriptan is well tolerated in children also
The maximum dose of Rizatriptan should not exceed 30 mg in 24 hours, and there should be a gap of 2 hours between two dosages
Rizatriptan has to be taken with a valid prescription under the supervision of a physician

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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एक स्वस्थ जीवन जीने और वज़न कम करने के लिए हम अलग-अलग तरीकों और स्वास्थ्यवर्धक काढ़ों जैसी चीज़ें आज़माते रहते हैं। अनगिनत स्वास्थ्य लाभों का वादा करने के अलावा, ये शरीर को डिटॉक्स करने और वज़न घटाने में मदद करने का भी दावा करते हैं। लेकिन एक पेय (ड्रिंक) है जो ऐसा करने में कामयाब

मशरूम (Mushroom in Hindi) के उपयोग, फ़ायदे, और न्यूट्रिशनल वैल्यू

परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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