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Remogliflozin Etabonate+Vildagliptin

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Molecule Summary

Uses
Type 2 diabetes mellitus
Therapy
Anti-Diabetic
Side Effects
Constipation, diarrhoea, asthenia, pyrexia, bacteriuria, urinary tract infection
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Molecule Description

Remogliflozin Etabonate+Vildagliptin is a combination of remogliflozin etabonate and vildagliptin, used to manage blood sugar levels in adults with type 2 diabetes, especially when other treatments, such as metformin alone, are not enough. It helps improve blood sugar control, especially after meals and throughout the day. It should be taken as advised by your doctor, usually with or after food to reduce side effects, and always at the same time each day. Remogliflozin works by helping your kidneys remove extra sugar from your body through urine, which may also lead to slight weight loss and lower blood pressure. Vildagliptin increases the release of insulin after meals and reduces sugar production in the liver, helping to maintain more stable blood sugar levels. These effects are most effective when combined with a healthy diet and regular physical activity. Common side effects may include constipation, diarrhoea, weakness, fever, and urinary tract infections. If you have any allergies to the ingredients, please inform your doctor before starting. If you miss a dose, take it with food as soon as you remember, unless it's almost time for your next dose, then skip the missed one. Do not take extra doses to make up for a missed dose. The medicine is generally safe with other common drugs for diabetes, blood pressure, and cholesterol, but it may slightly reduce the effectiveness of birth control pills and increase the risk of swelling when used with ACE inhibitors. It is also important to be cautious if you are using steroids, water pills, or cold medications, as they can affect how well this medicine works. Avoid using this medicine if you are pregnant or breastfeeding, as its safety is not known in such conditions. Let your doctor know if you have liver or kidney problems, or if you feel very tired, nauseous, short of breath, or have stomach pain, which could be signs of serious side effects. If you notice skin rashes, foot issues, pain in the genital area, or signs of infection, please report them immediately.

Uses

Remogliflozin Etabonate+Vildagliptin is used in adults aged 18 years and older with type 2 diabetes mellitus.

Contraindications

When should one not use Remogliflozin Etabonate+Vildagliptin

If you are allergic to remogliflozin etabonate & vildagliptin or any other ingredients of Remogliflozin Etabonate+Vildagliptin.

Side effects

Common side effects of this drug are:

  • Constipation
  • Diarrhoea
  • Asthenia
  • Pyrexia
  • Bacteriuria
  • Urinary tract infection

Precautions and Warnings

Pregnancy

Pregnancy

You should not use Remogliflozin Etabonate+Vildagliptin during pregnancy.

Breast Feeding

Breast Feeding

It is not known if Remogliflozin Etabonate+Vildagliptin passes into breast milk. You should not use Remogliflozin Etabonate+Vildagliptin if you are breastfeeding or plan to breastfeed.

Driving

Driving

You may feel dizzy while taking Remogliflozin Etabonate+Vildagliptin; do not drive or operate machinery.

Alcohol

Alcohol

No known information is available.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have type 1 diabetes, diabetic ketoacidosis, liver disease, or serious kidney problems, as these medicines may not be safe for you.
  • You feel very tired, nauseous, short of breath, or have stomach pain; these could be signs of serious side effects like pancreatitis or diabetic ketoacidosis.
  • You are on water pills, sulfonylureas (like glimepiride), or birth control pills, as these may interact or increase side effects like low blood sugar or reduced effectiveness.
  • You notice unusual skin issues, foot problems, urinary infections, or genital pain or swelling; these may be signs of rare but serious reactions.

Mode of Action

How Does It Work?

  • Remogliflozin Etabonate is a medicine used to help lower blood sugar levels in people with type 2 diabetes. It works by helping your kidneys remove excess sugar from your blood through urination. This helps reduce the amount of sugar in your body, which can lead to improved blood sugar control over time. It may also aid in weight loss and slightly lower blood pressure, which are additional benefits for many people with diabetes.
  • Vildagliptin is a medicine used to help control blood sugar levels in people with type 2 diabetes. It works by helping your body increase the amount of insulin released after meals and reducing the amount of sugar made by your liver. This helps keep your blood sugar more balanced throughout the day, especially after eating. Vildagliptin is most effective when used in conjunction with a healthy diet and regular exercise.

Interactions

Interactions with other medicines

  • Vildagliptin has a low chance of drug interactions and is generally safe with common diabetes, blood pressure, and cholesterol medicines like metformin, pioglitazone, amlodipine, and simvastatin.
  • Vildagliptin may have a slightly increased risk of swelling (angioedema) when taken with ACE inhibitors like ramipril.
  • Steroids, water pills, thyroid medicines, and certain cold medications may make vildagliptin less effective at lowering blood sugar.
  • Remogliflozin Etabonate is also unlikely to interact with most medicines, including metformin, diuretics, and bupropion.
  • It may slightly reduce the effectiveness of birth control pills, so use non-hormonal contraception during treatment.
  • Medicines that boost liver enzyme activity may make remogliflozin less effective.
  • There is a small risk of low blood sugar when remogliflozin is taken with glimepiride, but this was not seen in human studies.

Dosage

Overdose

If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you miss any dose of Remogliflozin Etabonate+Vildagliptin, take it as soon as you remember with food. However, if it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Frequently Asked Questions (FAQs)

When taken alone, the risk is low. But when combined with sulfonylureas like glimepiride, it may increase the risk. Watch for symptoms like shakiness, sweating, or dizziness.

Inform your doctor if you have liver or kidney issues, frequent infections, genital discomfort, or unusual fatigue. In rare cases, serious conditions like pancreatitis or diabetic ketoacidosis may occur.

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