Pyridostigmine

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Molecule Description

Pyridostigmine belongs to the group of anti cholinesterase medicines. It is used for treating myasthenia gravis, which involves weakness or rapid fatigue of muscles.

Uses

Myasthenia gravis
Constipation (paralytic ileus)
Inability to pass urine after an operation

Contraindications

When should one not use Pyridostigmine

Allergy to this medicine
Obstructive condition of stomach or intestine
Urinary obstruction
Chronic cough
Recently had coronary blockage (heart attack)

Side effects

Common side effects of this drug are:

Visual disturbance
Excessive watering of eyes
Irregular heartbeat
Low blood pressure
Fainting
Increased secretion of phlegm (mucus) than usual combined with constriction of the airways
Vomiting
Diarrhea
Stomach cramps
Rashes
Excessive sweating
Sudden urge to urinate

Precautions and Warnings

Pregnancy

This medicine should be avoided during pregnancy. Consult your doctor if you are pregnant or planning pregnancy.

Breast Feeding

This medicine is secreted into breastmilk. To be taken if advised explicitly by your doctor.

Driving

It may cause visual disturbance and affect the ability to drive. Be cautious while driving.

Alcohol

Avoid alcohol consumption when taking this medicine.

Other General Warnings

Talk to your doctor if

Tell your doctor if:
Have low blood pressure
Have a stomach ulcer
Have epilepsy
Have Parkinson’s disease
Have kidney problems
Heart disease
You are allergic to Pyridostigmine or any of the other ingredients
You have obstructive urinary or gastrointestinal issues
Respiratory illness (COPD, asthma)

Mode of Action

How Does It Work?

Pyridostigmine is a cholinesterase inhibitor. It stops the excessive activity of cholinesterase , potentiates the concentration of acetylcholine and helps muscles to work correctly.

Interactions

Interactions with other medicines

Steroids or other immunosuppressant medicines
Antimuscarinic medicines (e.g. Atropine, Hyoscine)
Medicines containing Methylcellulose
Muscle relaxants like Suxamethonium
Aminoglycoside Antibiotics
Medicines to treat irregular heartbeat

Interactions with food items

No specific food interactions reported.

Dosage

Overdose

Overdose symptoms may include nausea, vomiting, difficulty in breathing, muscle weakness, hallucinations, irregular heart beat and unsteadiness. Seek emergency medical care in case of an overdose of this medicine.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

No, it is not advised to take this medicine during pregnancy. Take only if considered essential by your doctor.

No, this medicine is not addictive. Take it as prescribed by your doctor. Do not alter the dosage or duration of this medicine by yourself.

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