Promethazine

Uses	Antiallergic, antiemetic
Therapy	Anti-Allergic, Anti-Emetic
Side Effects	Sleepiness, dizziness, headache, constipation

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Molecule Description

Promethazine is an anti-allergic medicine used for the treatment of allergic symptoms such as a runny nose, itching and rash. It is also used for the treatment of nausea and vomiting caused due to motion sickness. Promethazine works by opposing the action of histamine (natural substances produced in the body during allergic conditions). Sleepiness, dizziness, headache, constipation are some of the side effects of using this medicine, if the side effects do not go away on their own or your condition does not improve over time then inform your doctor.

Uses

It is used for the treatment of allergic symptoms such as a runny nose, itching and rash. It is also used for the treatment of nausea and vomiting caused due to motion sickness.

Contraindications

When should one not use Promethazine

If you are allergic to promethazine or any other ingredients of this medicine. If you have a rash, difficulty in breathing, a problem in swallowing, swelling of lips, tongue, throat and face after taking this medicine.
If you have taken any other medicines from the monoamine oxidase inhibitor group with this medicine or have taken it within 14 days before taking this medicine.
If you have severe dizziness, sleepiness, headache or unconsciousness.
If you are using this medicine for the treatment of a child of age less than 5 years.

Side effects

Common side effects of this drug are:

Sleepiness
Dizziness
Headache
Constipation
Feeling restless
Blurring of vision
A dry mouth

Precautions and Warnings

Pregnancy

Components of this medicine can cause harm to the unborn baby if taken during pregnancy. This medicine should not be taken by pregnant women unless your doctor has prescribed this medicine.

Breast Feeding

Components of this medicine can pass into the breastmilk and can cause harm to the breastfed baby if taken by a lactating mother. This medicine should not be taken by a lactating mother.

Driving

This medicine can cause sleepiness. Avoid driving if you have sleepiness after taking this medicine.

Alcohol

Consumption of alcohol with this medicine can increase sleepiness. Therefore, avoid drinking alcohol while you are taking this medicine.

Other General Warnings

Talk to your doctor if

You have pre-existing medical conditions like breathing problems, liver, heart or kidney diseases, fits, etc.
You have an obstruction in the stomach or difficulty in urination.
You have difficulty while hearing.
Your eye pressure is increased.
You have loose motion or sleepiness after having a viral illness.
You have indigestion after taking some sugars.

Mode of Action

How Does It Work?

It works by opposing the action of histamine (natural substances produced in the body during allergic conditions). Histamine is responsible for allergic symptoms and thus blocking its actions helps to get rid of the allergies.

Interactions

Interactions with other medicines

Certain medicines can interfere with the action of Promethazine or Promethazine itself can affect the action of other medicines taken at the same time.
Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for any disorders.
Tell your doctor in particular if you are taking medicines for respiratory problems like asthma (such as theophylline) or bowel diseases along with Promethazine, as it can cause dizziness, blurring of vision and a dry mouth.
Concomitant use of other medicines such as diazepam, zolpidem (used in brain diseases) with this medicine can increase sleepiness.
Concomitant use of aspirin (painkiller) with this medicine can hide the side effects of Promethazine.

Dosage

Overdose

Symptoms of an overdose in children include seizures, difficulty in breathing, abnormal movements of hand and feet, unusual perception, etc. Symptoms of an overdose in adults include sleepiness, seizures, loss of consciousness, difficulty in breathing, etc. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of this medicine then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow your regular dosing schedule.

Frequently Asked Questions (FAQs)

Promethazine should not be taken for more than 7 days. If your condition is not relieved after using this medicine for 7 days, consult your doctor immediately.

While taking Promethazine you should avoid going in direct sunlight, as doing so can make your skin sensitive to sunlight. Consult your doctor if your skin becomes sensitive to sunlight.

If you have a dry mouth after taking Promethazine you should drink plenty of water, suck sugarless candy or ice chip or chew sugarless gum.

Promethazine can cause constipation as a side effect of using this medicine. Consult your doctor if constipation persists.

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