Prochlorperazine

Description

Prochlorperazine is a medicine commonly used to relieve nausea, vomiting, and d

izziness, including those caused by migraines or after surgery. It works by blocking certain chemical signals in the brain, especially dopamine, that trigger nausea, helping you feel more stable and comfortable. This medicine can also help with vertigo and balance-related problems. Always use it exactly as advised by your doctor and inform them about any existing health conditions or other medicines you are taking to ensure safe and effective treatment.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses

Prochlorperazine is used for the treatment of nausea, vomiting, post operative vomiting & migraine induced vomiting.

Contraindications

When should one not use Prochlorperazine

If you are allergic to prochlorperazine

Side effects

Common side effects of this drug are:

Drowsiness
Dizziness
Amenorrhea
Blurred vision
Skin rash
Dry mouth

Precautions and Warnings

Pregnancy

Can I take Prochlorperazine during pregnancy?

There is limited information about the effect of Prochlorperazine on pregnancy. Thus, you should not consume this medicine unless prescribed by your doctor after assessing the need and benefit. Talk to your doctor if you are pregnant, think you may be pregnant, or are planning a pregnancy.

Breast Feeding

Can I take Prochlorperazine while breastfeeding?

Prochlorperazine may pass into the breastmilk. Thus, it is advisable to avoid breastfeeding while on this medicine.

Driving

Can I drive if I have consumed Prochlorperazine?

If you experience drowsiness after taking Prochlorperazine, then it is advised to avoid driving.

Alcohol

Can I consume alcohol with Prochlorperazine?

You should not consume alcohol along with this medicine, as it may increase the risk of side effects. Talk to your doctor if you consume it often.

Other General Warnings

Talk to your doctor if

You have heart problems or a history of heart disorders.
You have thyroid, liver, or kidney problems.
You have a tumor of the adrenal glands or a prostate problem.
You have fits or are suffering from Parkinson's disease.
You have low blood levels of calcium, potassium, and magnesium.
You have a history of alcohol consumption.
You have a stroke, low mood, blood clot disorder, diabetes, etc.
You are an elderly patient. Prochlorperazine may increase sensitivity to sunlight.
You should avoid exposure to direct sunlight while taking this medicine.

Mode of Action

How Does It Work?

Prochlorperazine works by blocking the action of dopamine receptors in the brain, which is responsible for causing nausea and vomiting.

Interactions

Interactions with other medicines

Some medicines can affect the way Prochlorperazine works, or Prochlorperazine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, an...
Read more
Medicines used for irritable bowel syndrome, asthma (anticholinergic medicines) may reduce the effectivity leading to constipation or heart stroke.

Dosage

Overdose

If you take more Prochlorperazine than you should, immediately contact your doctor as taking too much. Prochlorperazine may cause symptoms such as feeling sleepy or dizzy, increased or rapid heartbeat...
Read more

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose ...

Content Details

WRITTEN BY

Ravindra Ghongade

B. Pharm

REVIEWED BY

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery), WHO FIDES member

Frequently Asked Questions (FAQs)

Q: Can Prochlorperazine cause photosensitivity?

A: Yes, direct exposure to sunlight, while on Prochlorperazine, can cause your skin to be more sensitive to light. Thus, you should avoid exposure to direct sunlight to prevent photosensitivity. Always apply sunscreen before going out.

Q: Is Prochlorperazine addictive?

Prochlorperazine is not known to possess addictive properties. Talk to your doctor for more information.

Q: Can I stop taking Prochlorperazine if I start feeling better?

No, you should not stop taking Prochlorperazine even if you start feeling better after starting the treatment with this medicine. Always complete the course of treatment as advised by your treating do...
Read more

References

View All

Last Updated on: 10 Dec 2025 | 04:24 AM (IST)

Share This With Your Friends

Recent articles

See All

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.