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molecule

Probenecid

Molecule Description

Probenecid is a uricosuric agent that helps the body to pass uric acid via urin

e, which in turn lowers the level of uric acid in blood.

uses

Uses of Probenecid

  • High uric acid levels (gout and gouty arthritis)
  • To prolong the action duration of some antibiotics like Penicillin
contraindications

Contraindications of Probenecid

When should one not use Probenecid

  • Allergy to this medicine
  • Children below two years of age
  • Kidney failure
  • Severe dehydration
  • Blood disorders
  • Kidney stones
sideEffects

Side effects of Probenecid

Common side effects of this drug are:

  • Headache
  • Joint pain
  • Nausea
  • Vomiting
  • Loss of appetite
  • Itching and rashes
  • Hair fall
  • Increased desire to pass urine
  • Anaemia
  • Unsteadiness
  • Pain in the abdominal area
  • Blood in urine
  • Severe side effects include liver and kidney disorders
precautionsAndWarnings

Precautions and Warnings of Probenecid

pregnancy

Pregnancy

Q:
Can I take Probenecid during pregnancy?
A:
Consult your doctor while taking this medicine if you are pregnant or planning a pregnancy. This medicine may cause harm to the baby and thus the benefits need to outweigh the risks.
breastfeeding

Breast Feeding

Q:
Can I take Probenecid while breastfeeding?
A:
You should consult a doctor if you are a breastfeeding mother.
driving

Driving

Q:
Can I drive if I have consumed Probenecid?
A:
This medicine may affect your alertness. Drive only if you feel comfortable.
alcohol

Alcohol

Q:
Can I consume alcohol with Probenecid?
A:
Limited intake of alcohol is advised while taking this medication. It may raise the level of uric acid in blood.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • Tell your doctor if-
  • You observe any signs of allergy – rashes, hives, swelling on face, etc. after taking this medicine
  • You have stomach ulcers
  • You find blood in urine
  • Your pain of arthritis worsens after taking this medicine
  • You are suffering from any medical condition
  • You are taking any medication (your doctor might adjust the doses of certain medicines when taking along with Probenecid)
modeOfAction

Mode of Action of Probenecid

How Does It Work?

It acts on the kidneys and increases the excretion of uric acid from the body by preventing its reabsorption into the blood. It thus lowers blood uric acid level.
interactions

Interactions of Probenecid

Interactions with other medicines

  • Captopril
  • Ketoprofen
  • Naproxen
  • Penicillins
  • Methotrexate and Acyclovir
  • Avoid Salicylate with this medicine

Interactions with food items

No information available.
dosage

Dosage of Probenecid

Overdose

Overdose of Probenecid includes symptoms like drowsiness, stomach upset, vomiting, convulsions, breathlessness and nausea. Immediately contact a healthcare provider if an overdose is suspected.

Missed a Dose

If you have missed the Probenecid regular dose, then take the missed dose as soon as you remember it. If it is almost time for the next dose, then skip the missed dose and continue with the subsequent...
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Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What special precautions should I follow?

A: Probenecid may cause kidney problems, so drink plenty of water to prevent kidney stones. It also causes dizziness, so avoid driving and operating heavy machines. Patients with a history of peptic ulcers should be careful while taking this medicine.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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