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Molecule Description

Prasugrel is used to prevent the formation of blood clots.

Uses of Prasugrel

Prasugrel is used in combination with low dose Aspirin in patients with chest pain, stroke, and heart attacks that have undergone angioplasty procedures (a procedure to open blocked blood vessels that supply blood to the heart). In some processes, a tube (stent) is placed in one or more coronary arteries. Prasugrel is used to prevent thrombosis.
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Contraindications of Prasugrel

When should one not use Prasugrel

  • Allergic to the medicine
  • Stomach ulcers
  • Severe liver diseases
  • Any conditions that cause bleeding in the intestines
  • Hemophilia and other diseases that show bleeding tendencies

Side effects of Prasugrel

Common side effects of this drug are:

  • Dizziness
  • Excessive fatigue
  • Cough
  • Decreased urination
  • Headache, confusion
  • Nausea, stomach pain
  • Itching rashes
  • Numbness or weakness
  • Fever
  • Yellowish discoloration of skin

Precautions and Warnings of Prasugrel


Can I take Prasugrel during pregnancy?
This medicine is probably unsafe to use in pregnant women. Discuss with your doctor before consuming this medicine.

Breast Feeding

Can I take Prasugrel while breastfeeding?
No specific information is available on the use of Prasugrel during breastfeeding. Hence it is better not to use unless prescribed by a physician.


Can I drive if I have consumed Prasugrel?
This medicine probably does not affect your ability to drive.


Can I consume alcohol with Prasugrel?
Use of alcohol while using this medicine may increase your risk of stomach bleeding.

Other General Warnings

Talk to your doctor if
  • This medicine is not for use in children and adolescents who are below 18 years of age
  • Elderly above 75 years of age
  • Any recent surgery
  • Any history of bleeding disorders
  • Bodyweight less than 60 kg
  • Any history of kidney disease

Mode of Action of Prasugrel

How Does It Work?

Prasugrel is an inhibitor of platelet (type of blood cells) activation and aggregation. This prevents platelets from forming a clot, and the blood can flow easily.

Interactions of Prasugrel

Interactions with other medicines

  • Blood thinners such as Warfarin, Heparin
  • Non-Steroidal Anti-Inflammatory Drugs (pain killers) such as Ibuprofen and Naproxen

Interactions with food items

Avoid alcohol while on treatment with Prasugrel as it increases the side effects.

Dietary Restrictions of Prasugrel

No information is available on dietary restrictions while you are taking Prasugrel, consult your doctor or pharmacist for further details.

Dosage of Prasugrel


If you take an overdose of Prasugrel, the complications may be fatal. Any of the known side effects of Prasugrel, especially bleeding symptoms, can be seen in an overdose. You must seek emergency medical attention immediately.
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Missed a Dose

Take the missed dose as soon as you remember. If you have missed a dose then do not take extra medicine to compensate for the missed dose.

Content Details


Dr. Rukman Mecca

MBBS, MD (Community Medicine)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Any precautions to be taken before starting on while on the treatment?

  • Inform your doctor if you are due to undergo any surgeries, including dental procedures or heart bypass surgery
  • Monitor bleeding and clotting investigation profile while on treatment with Prasugrel
  • If you notice the following symptoms while on therapy with Prasugrel, inform your doctor immediately
  • Unexplained or severe bleeding
  • Blood in urine or motion
  • Vomiting out blood
  • Coughing out blood

Q: What should I know regarding the storage of medication?

  • Store this medicine at room temperature should be away from excess heat and moisture
  • Keep out of the reach of children

Q: When and how to consume the medicine?

A: Prasugrel comes in the tablet or capsule form taken orally after a meal.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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