Polystyrene Sulfonate

Uses	High potassium levels
Therapy	Drug For Chronic Kidney Disease
Side Effects	Nausea, vomiting, constipation, low potassium levels

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Molecule Description

Polystyrene Sulfonate reduces high potassium levels in your blood, a condition known as hyperkalaemia. It works by removing the extra potassium in your body. It can be used in both adults and children. Take this medicine strictly as recommended by your doctor. Other orally administered medications may bind to Polystyrene Sulfonate, reducing their absorption and efficacy. Co-administration with other oral medications is not recommended. Polystyrene Sulfonate should be taken at least 3 hours before or after other oral medications and 6 hours apart for patients with gastroparesis. Avoid using sorbitol at the same time. Seek medical attention if you are experiencing severe abdominal pain, nausea, vomiting, stomach distension or rectal bleeding. Keep an eye out for other electrolyte imbalances caused by calcium and magnesium binding. If you experience clinically significant constipation, stop using Polystyrene Sulfonate. Laxatives containing magnesium should be avoided. Those on low-salt diets or at risk of sodium-related health problems should monitor their sodium intake. Patients suffering from congestive heart failure, hypertension, kidney damage or oedema should be closely monitored.

Uses

Polystyrene Sulfonate is used for reducing high levels of potassium in the blood in adults and children.

Contraindications

When should one not use Polystyrene Sulfonate

If you are allergic to polystyrene sulfonate or any other ingredient of Polystyrene Sulfonate.
If you have low levels of potassium in your blood.
If your stomach/intestine is partially or completely blocked.
In infants less than four weeks of age and/or with reduced movement of the stomach/intestine, Polystyrene Sulfonate should not be given orally.

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Constipation
Low potassium levels

Precautions and Warnings

Pregnancy

There is limited information on the effect of Polystyrene Sulfonate in pregnancy. This medicine should only be used in pregnant women if recommended by the doctor after assessing the need and the risk.

Breast Feeding

No information is available if Polystyrene Sulfonate passes into human breast milk. Polystyrene Sulfonate may be used in breastfeeding women only if recommended by the doctor after assessing the need and the risk.

Driving

There is limited information on the effect of Polystyrene Sulfonate on driving ability. If you experience any symptoms which may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

There is limited information available regarding the interaction of alcohol with Polystyrene Sulfonate. Ask your doctor for advice on alcohol intake along with Polystyrene Sulfonate.

Other General Warnings

Talk to your doctor if

You take any other oral medicines for other diseases.
You have heart or kidney problems.
You have high blood pressure.
You have swelling in your arms or legs.
Your child was prematurely born, had a low birth weight, or has decreased movement of the stomach/intestine.
You develop symptoms like muscle pain/cramps, headaches, increased thirst, dizziness, restlessness, tiredness, confusion, sleeplessness after using this medicine.
You experience constipation after taking this medicine.

Mode of Action

How Does It Work?

Polystyrene Sulfonate is an ion-exchange resin that works by exchanging potassium ions in the body with other ions. Thus, Polystyrene Sulfonate removes the extra potassium in the body and brings the potassium levels back to normal.

Interactions

Interactions with other medicines

Some medicines can affect the way Polystyrene Sulfonate works or Polystyrene Sulfonate itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
Polystyrene Sulfonate should not be used if you are taking a sugar-free sweetener called sorbitol.
Particular care should be taken if you are taking medicines for constipation that contain magnesium or aluminium (magnesium hydroxide, aluminium carbonate, aluminium hydroxide), heart failure (digoxin), thyroid disorders (thyroxine, levothyroxine), mental illness (lithium), medicines that contain salts such as magnesium or potassium.

Dosage

Overdose

The symptoms of an overdose of Polystyrene Sulfonate are irritability, muscle weakness, slowed thought process.

Missed a Dose

If you have missed taking a dose of Polystyrene Sulfonate take it as soon as you remember it. If it's time for the next dose, skip the missed dose and continue with the regular dose schedule. Avoid taking a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Polystyrene Sulfonate exchanges potassium ions in the body with other ions. Thus, Polystyrene Sulfonate removes the extra potassium in the body and brings the potassium levels back to normal.

You should inform your doctor if you have kidney disease. Your doctor will recommend whether Polystyrene Sulfonate is suitable for you.

Polystyrene Sulfonate may cause diarrhoea in some individuals. If diarrhoea occurs, it is recommended to stay hydrated.

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