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Papaverine

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Molecule Summary

Uses
Erectile dysfunction
Therapy
Drugs For Erectile Dysfunction
Side Effects
Dizziness, tiredness, abdominal discomfort, headache, difficulty in breathing, chest pain, weakness, hypotension
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Molecule Description

Papaverine is an opium alkaloid isolated from a plant known as Papaver somniferum, and then it is synthesised. It can be used for the treatment of erectile dysfunction.

Uses

  • Erectile dysfunction

Contraindications

When should one not use Papaverine

  • If you have an allergy to Papaverine.
  • If you have a complete AV heart block (a type of heart block in which the conduction is completely blocked between atria and ventricles).

Side effects

Common side effects of this drug are:

  • Difficulty in breathing.
  • Chest pain.
  • Weakness.
  • Hypotension (drop in blood pressure).

Precautions and Warnings

Pregnancy

Pregnancy

No, it is not indicated for use in pregnant women.

Breast Feeding

Breast Feeding

No, it is not indicated for use in breastfeeding mothers.

Driving

Driving

Papaverine can cause drowsiness and sleepiness, so you must avoid driving while you are on treatment with this medicine.

Alcohol

Alcohol

You must avoid alcohol as it can increase the side effects caused by Papaverine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have heart block.
  • You have high blood pressure
  • You've glaucoma (increased pressure in the eye)

Mode of Action

How Does It Work?

Papaverine acts by bringing about the relaxation of smooth muscles surrounding the blood vessels of the penis. As a result of this relaxation, the blood flow to the penis is increased, and this causes the penis to become erect when the person is sexually aroused. This medication doesn't act if the person is not sexually stimulated.

Interactions

Interactions with other medicines

  • Any medicine which makes you feel sleepy e.g. Alprazolam, clonazepam(sleeping pills), should be avoided with Papaverine.

Interactions with food items

  • Talk to your doctor if you find anything abnormal with a specific food while treating this medicine.

Dosage

Overdose

Symptoms of overdose are vomiting, blurred vision, Tachycardia (fast heartbeat), flushing, abnormal eye movements. Rush the patient to a nearby hospital as early as possible or call the poison control helpline or any emergency helpline.

Missed a Dose

Since this medicine is given under supervision, the chances to miss it are rare.

Frequently Asked Questions (FAQs)

It may be habit-forming, so its long term use must be avoided.

It can last between 3 to 4 hours.

Although it lowers blood pressure due to its relaxing effect on smooth muscles of blood vessels, it is not recommended to treat high blood pressure.

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