Mitomycin

Uses	Cancer
Therapy	Anti-Neoplastic
Side Effects	Nausea, vomiting, low platelet count, bone marrow suppression

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Molecule Description

Mitomycin is an anti-cancer medicine. It is used to treat various kinds of metastatic and advanced cancer (that spreads in the body) such as breast, stomach, lungs or pancreas. It acts by killing cancer-causing cells, thereby preventing the spread of cancer cells. This medicine will be given by a doctor or nurse at a hospital or clinic.

Uses

It is used to treat stomach, breast, lung or pancreatic cancer that has spread to other parts of the body.

Contraindications

When should one not use Mitomycin

If you are allergic to Mitomycin or any other ingredient of this medicine.
If you have decreased blood cell count, such as low platelets, low white blood cells, etc.
If you are breastfeeding.

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Bone marrow suppression
Decreased white blood cells
Decreased platelets
Cough
Shortness of breath

Precautions and Warnings

Pregnancy

Mitomycin may cause harm to the unborn baby if used during pregnancy. Thus, this medicine should not be used during pregnancy unless advised by your doctor.

Breast Feeding

Mitomycin passes into the breast milk, thus it should not be used by a nursing mother.

Driving

If you experience altered consciousness after taking this medicine, it is advised to avoid driving.

Alcohol

You should avoid consuming alcohol while on Mitomycin. Talk to your doctor if you consume it often.

Other General Warnings

Talk to your doctor if

You have kidney disease or are on any other medicine that alters kidney function.
You are on dialysis.
You are allergic to this medicine or have had any other undesired side effects.
You have or had liver or lung disease.
You have or had bone marrow failure.
You are pregnant, planning a pregnancy or breastfeeding.
You have low haemoglobin, low blood count or altered blood function.
You are elderly.
You had or have planned live vaccination such as yellow fever.

Mode of Action

How Does It Work?

The growth and multiplication of cells take place through DNA, a genetic material. Mitomycin works by inhibiting the growth and multiplication of cancer cells by stopping them from making DNA, resulting in cell death.

Interactions

Interactions with other medicines

Some medicines can affect the way Mitomycin works or Mitomycin itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking other cancer medicines or vitamin supplements.
If you are taking or have recently taken any live vaccine such as yellow fever.

Dosage

Overdose

Your doctor or nurse will give this medicine so it is unlikely that you overdose on this medicine. Overdose of Mitomycin may cause serious effects such as bone marrow suppression, nausea and vomiting. Seek urgent medical help if you think you have been given too much of this medicine.

Missed a Dose

You will be monitored by your doctor or nurse as to when Mitomycin should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.

Frequently Asked Questions (FAQs)

Mitomycin is an anti-cancer medicine used to treat various types of cancers. It is used to treat advanced and metastatic (spreading) cancer such as breast, pancreas, stomach and lungs.

Do not stop Mitomycin treatment until and unless your doctor advises you. If you stop this treatment, it can lead to an incomplete killing of cancer cells and thus increase the risk of reoccurrence of cancer. The doctor will gradually decrease the dose as per the need.