Mefenamic Acid+Tranexamic

When should one not use Mefenamic Acid+Tranexamic

• If you are allergic to mefenamic acid, tranexamic acid or any of the ingredients of Mefenamic Acid+Tranexamic.
• If you have a history of stomach or intestinal bleeding due to painkillers.
• If you have or have ever had a blood clot in your blood vessels (thrombosis).
• If you have a severe liver, kidney or heart function problem.
• If you have a bleeding disorder.
• If you recently had a bypass surgery of the heart.
• If you have a history of convulsions or inflammatory bowel disease.
• This medicine should not be taken in the last trimester of pregnancy.

Common side effects of this drug are:

• Diarrhoea
• Back pain
• Headache
• Muscle pain
• Nausea
• Constipation
• Ringing in the ears
• Bloating

Other General Warnings

• You have any medical history especially of bleeding in the brain (subarachnoid haemorrhage) and a history of blood clots (such as in the legs, lung, brain or eye).
• You are suffering from certain heart diseases (irregular heartbeat, heart valve problems) and blood clotting disorders.
• You have a kidney function problem or you are passing blood in the urine.
• You have epilepsy, seizures (fits) or respiratory disorders such as asthma.
• You experience visual disturbances after taking this medicine, discontinue the treatment immediately.
• You should not take Mefenamic Acid+Tranexamic if you have an irregular menstrual bleeding pattern.
• You are an elderly person, there is an increased risk of side effects such as ulcers and bleeding.
• You are taking oral contraceptives, be cautious as there is a risk of thrombosis.
• Mefenamic Acid+Tranexamic can impair your fertility. Thus, you should not take this medicine if you are trying to conceive or taking treatment of fertility.

How Does It Work?

• Mefenamic Acid+Tranexamic works by the combined action of its two components Tranexamic acid and Mefenamic acid.
• Tranexamic acid works by improving the blood clotting by preventing or slowing down the process of break down of blood clots called fibrinolysis.
• Mefenamic acid helps in relieving the sensation of pain by inhibiting the formation of inflammatory mediators such as prostaglandin which is responsible for pain and swelling.

Interactions with other medicines

• Sometimes Mefenamic Acid+Tranexamic may affect the way other medicines work and other medicines may affect how this medicine works if taken at the same time. Discuss with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible interactions.
• In particular, if you are taking medicines like blood thinners (like warfarin, heparin), antidiabetic medicines, heart-related medicines, anti-hypertensive medicines, antibiotics like gentamicin, chloramphenicol, anti-HIV medicines, etc.
• The effect of Mefenamic Acid+Tranexamic will be reduced if taken along with blood thinners (like warfarin, heparin) which are medicines that inhibit clot formations.
• An additive effect may be seen if the patient is taking medications that increase blood clot formation (like aprotinin).
• Oral contraceptive pills, when taken with Mefenamic Acid+Tranexamic, may promote blood clot formation which can be harmful, leading to blockage of blood vessels by abnormal clot formation. Inform your doctor if you are taking birth control pills.

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