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Levonorgestrel+Ethinylestradiol

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Molecule Summary

Uses
Oral contraceptive
Therapy
Female Hormone Pills
Side Effects
Headache, nausea, acne, nervousness, weight gain
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Molecule Description

Levonorgestrel+Ethinylestradiol is an oral contraceptive pill containing a combination of two active medicines, levonorgestrel and ethinylestradiol. It works by preventing the release of the egg and restricting the movement of the sperm in the womb. Thus, blocking its union with the egg. Take this medicine as prescribed and for the duration. Do not take this medicine if you are pregnant, breastfeeding, have any liver or pancreas problems or have cancer of the breast, uterus or vagina. Inform your doctor, if you are above 35 years or smoke and about all the medicines, herbs and supplements you take and all the conditions or diseases you suffer from before starting this medicine.

Uses

Levonorgestrel+Ethinylestradiol is used as an oral contraceptive for women.

Contraindications

When should one not use Levonorgestrel+Ethinylestradiol

  • If you are allergic to levonorgestrel or ethinylestradiol or any other ingredients of this medicine.
  • If you have a history of any blood clot formation or bleeding disorder.
  • If you have heart or blood vessel problems like stroke, heart attack or chest pain, or serious or uncontrolled high blood pressure.
  • If you have or had a history of migraine attacks.
  • If you had or have pancreas or liver problems.
  • If you have a history of vaginal bleeding (cause not established), absent periods for more than 3 months (amenorrhea).
  • If you have or are suspected of having breast cancer or cancer of the genital organs (private parts).
  • If you are taking treatment for Hepatitis C with a medicine that contains Ombitasvir/Paritaprevir/Ritonavir plus Dasabuvir.

Side effects

Common side effects of this drug are:

  • Headache
  • Acne
  • Nausea
  • Nervousness
  • Stomach discomfort like pain, bloating
  • Depression
  • Weight gain
  • Painful menstruation

Precautions and Warnings

Pregnancy

Pregnancy

Levonorgestrel+Ethinylestradiol should not be used during pregnancy as it is used to stop or prevent pregnancy. When pregnancy is detected, this medicine should be discontinued immediately and you should consult your doctor.

Breast Feeding

Breast Feeding

Levonorgestrel+Ethinylestradiol should not be used during breastfeeding as it passes into the breastmilk and may harm the breastfed baby. Moreover, it may also lead to a reduction in the amount of milk produced and may affect its quality. You should consult your doctor before using this medicine during breastfeeding.

Driving

Driving

It is not expected that Levonorgestrel+Ethinylestradiol will affect your ability to drive but if you do not feel well or are unable to be alert, you should avoid driving.

Alcohol

Alcohol

The consumption of alcohol does not affect the efficacy of Levonorgestrel+Ethinylestradiol. This medicine can enhance the effects of alcohol and affect you adversely. Hence, it is best advised to avoid consuming alcohol while taking this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a family history of breast cancer, diabetes, fits or other brain disorders.
  • You have diabetes, high blood pressure or cholesterol.
  • You have a disease of the liver, gall bladder or inflammatory bowel disease (Crohn's disease or ulcerative colitis).
  • You have a blood disease that damages the kidneys (hemolytic uremic syndrome).
  • You have an immune system disorder like systemic lupus erythematosus (SLE).
  • You have a history of pregnancy patches especially on the face (chloasma).
  • You have a disease that first appeared during pregnancy like porphyria (a rare inherited metabolic disorder), hearing loss, gestational herpes (vesicular skin rashes during pregnancy) and Sydenham's chorea (rapid, irregular movements of the body).
  • You have a family history or previous history of serious allergic reactions causing swelling of the face and throat, breathing difficulty, skin rashes and blisters (hereditary angioedema).
  • You should let the doctor or the laboratory person know that you are using this medicine while going for a lab test, as this medicine may interfere with the lab tests.

Mode of Action

How Does It Work?

Levonorgestrel+Ethinylestradiol is an oestrogen-progestogen combination that works by preventing the release of the egg by the ovary, thickening vaginal secretions (blocking the sperm from reaching the egg) and thinning down the lining of the uterus. It helps in preventing the implantation of the egg if it is fertilized by any chance, thus preventing pregnancy.

Interactions

Interactions with other medicines

  • Levonorgestrel+Ethinylestradiol may interact with other medications and provide an altered response to the treatment. Please notify your doctor if you are undergoing any other treatments, over-the-counter medications (that you buy without a prescription) and herbal preparations.
  • Concomitant use of Levonorgestrel+Ethinylestradiol along with medicines used to treat fits (phenytoin, carbamazepine, etc), anti-HIV medicines like ritonavir, anti-infectives like penicillin, herbal supplements like St. John's Wort (used to treat a psychiatric illness), may alter the effects of Levonorgestrel+Ethinylestradiol.
  • Concomitant use of this medicine with certain antiviral medicines may affect your liver enzymes. Thus, this medicine should be stopped and can be restarted 2 weeks after completing the treatment.
  • Other medicines that should be used with caution are anti-tuberculosis medicines like rifampicin and anti-epileptic medicines like carbamazepine, immunosuppressants like ciclosporin, etc.

Dosage

Overdose

The symptoms of an overdose are nausea, vomiting or withdrawal bleeding. If you experience any of the symptoms or think you have taken too much of Levonorgestrel+Ethinylestradiol, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Missing a dose of Levonorgestrel+Ethinylestradiol may reduce the effectiveness of the treatment. If you have missed any dose of this medicine, take it as soon as you remember and continue with your regular dosing schedule. You should also inform your doctor and seek further advice.

Frequently Asked Questions (FAQs)

You should take Levonorgestrel+Ethinylestradiol in the correct doses and for the exact duration as told by your doctor. You need to swallow it, with water and not chew, cut or break it. You need to take it regularly and at a fixed time.

No, you should not stop taking Levonorgestrel+Ethinylestradiol midway. You must finish the full course of treatment. Stopping the medication can lead to treatment failure. You need to consult your doctor if you have any concerns.

Do not stop taking Levonorgestrel+Ethinylestradiol on your own. Do not use combinations of hormonal contraceptives like pills, patches or rings all at one time. Stick to any one method. Be cautious if you are older than 35 years, overweight, have a family history of thrombosis or clot formation. Discuss with your doctor before taking this medicine if you have high cholesterol, high blood pressure, migraine or heart disease. Be watchful of your diet, weight gain and any metabolic disorders.

No, Levonorgestrel+Ethinylestradiol is not meant for use in irregular periods.

Yes, you may experience an increase in your weight after treatment with Levonorgestrel+Ethinylestradiol.

Withdrawal bleeding is the bleeding that occurs when a woman on hormonal contraception such as pills, patches or the vaginal ring suddenly stops using them. It is not the same as menstrual bleeding and is much lighter and of shorter duration than a normal menstrual period. However, not everyone gets this when they stop using contraceptive measures.

No, you should not smoke while on treatment with Levonorgestrel+Ethinylestradiol, as cigarette smoking may increase the risk of heart problems.

No, Levonorgestrel+Ethinylestradiol is used to prevent pregnancy; it does not delay or postpone periods.

No, Levonorgestrel+Ethinylestradiol is not an emergency contraceptive pill.

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