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Lercanidipine

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Molecule Description

Lercanidipine is ‘calcium channel blocker’ medicine that lowers high blood pressure (hypertension).

Uses

High blood pressure.

Contraindications

When should one not use Lercanidipine

  • Do not take this medicine if:
  • You are allergic to this medicine or other calcium channel blocker medicines
  • You have heart failure
  • You have severe kidney disease
  • You have severe liver disease
  • You have unstable angina
  • You are pregnant
  • You are breastfeeding
  • You are taking Ciclosporin, antifungal medicine, Macrolide antibiotics, antiviral medicine

Side effects

Common side effects of this drug are:

  • Angina
  • Chest pain
  • Decrease in blood pressure
  • Allergic reaction

Precautions and Warnings

Pregnancy

Pregnancy

This medicine should not be taken in pregnancy as it can harm an unborn baby. Consult with the doctor before taking medicine.

Breast Feeding

Breast Feeding

No data available whether this medicine passes in breast milk or not. Therefore avoid this medicine during breastfeeding. Consult with the doctor before taking medicine.

Driving

Driving

It may impair the ability to drive. You may feel dizziness, drowsiness.

Alcohol

Alcohol

Patients should not consume alcohol while taking this medicine as it can cause dizziness, tiredness as it further decreases the blood pressure.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have heart disease called sick sinus syndrome or angina
  • You have liver disease
  • You are on dialysis for kidney disease

Mode of Action

How Does It Work?

Lercanidipine blocks L-type calcium channels in the smooth muscle cells of blood vessels, relaxing them, and thus lowering blood pressure.

Interactions

Interactions with other medicines

  • Antacids like Cimetidine and Ranitidine
  • Itraconazole
  • ketoconazole
  • Erythromycin
  • Phenytoin
  • Ritonavir
  • Simvastatin
  • Carbamazepine
  • Rifampicin
  • Beta-blockers like Metoprolol
  • Diuretics
  • Digoxin

Interactions with food items

  • The medicine should be taken at least 15 minutes before breakfast, as a diet rich in fat increases medicine level in the blood
  • Grapefruit or its juice increases the effect of medicine
  • The patient should reduce salt intake, eat more potassium-rich foods, avoid caffeine

Dietary Restrictions

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further information.

Dosage

Overdose

The effect of an overdose may be harmful as it may further lower your blood pressure that may lead to unconsciousness and you may require immediate medical attention.

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Inform the doctor about your detailed medical and surgical historyInform your physician if you have any of the following conditions:Liver diseaseHeart disorderKidney diseaseIf you are pregnant, lactating or planning a pregnancy

Low salt intake dietDaily Regular exercise and walkingUse of sunflower or safflower cooking oilDecrease body weight according to height

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References:

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