Lamivudine
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Molecule Description
Lamivudine is a medicine used to control certain complicated viral infections such as HIV/ AIDS and Hepatitis B in combination with other medicines. This medicine is classified as an ‘antiviral.’
Uses
- Lamivudine is used along with other medications to treat Human Immunodeficiency Virus (HIV) infection in adults and children
- This medicine is also used to treat viral infection of the liver, but only at a lower dose (Hepatitis B infection), which is not severe (compensated liver disease) or which is very critical (decompensated liver disease), in adults
Contraindications
When should one not use Lamivudine
Allergy to Lamivudine or any other components of the medicine.
Side effects
Common side effects of this drug are:
- Headache, feeling sick (nausea), vomiting, generalized discomfort
- Stomach pain, loose motions
- Fever, muscle and joint pains
- Cough, running nose
- Rashes, hair loss
- Difficulty in sleeping
- Decreased red blood cell counts (anemia), platelets (thrombocytopenia) or a type of white blood cells (neutropenia), elevated liver enzymes
- Severe allergic reactions causing facial and throat swelling, difficulty in swallowing and breathing with or without rashes, itching; infections of the pancreas; breakdown of muscle; enlarged liver
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have or had any liver or kidney disease in the past
- You are obese/ overweight (women need to be more careful)
- You or your child have kidney problems
Mode of Action
How Does It Work?
Lamivudine works by interfering with multiplication or replication of the genetic material (DNA or RNA) of the virus; this will reduce the virus load in the blood and will bring the infection under control.
Interactions
Interactions with other medicines
- If you regularly take medicines containing Sorbitol or other sugar alcohols (Xylitol, Mannitol, Lactitol, Maltitol)
- Other medicines containing Lamivudine or a closely related medicine used to treat HIV/ AIDS (Emtricitabine)
- Co-trimoxazole (antibiotic) or Cladribine (used to treat a type of white blood cell cancer)
Interactions with food items
Lamivudine can be taken with or without meals.
Dietary Restrictions
No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further information.
Dosage
Overdose
Unintentional overdose with Lamivudine may not be harmful. Seek medical attention if you feel uncomfortable following the overdose.
Missed a Dose
Take the missed dose as soon as you remember. Skip the missed dose if it is too late. But, do not take a higher or a double dose to compensate for the missed dose.
Frequently Asked Questions (FAQs)
Articles
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References:
- EMC lamivudine. [accessed on 14 Sep,2019](Online)
- EMC lamivudine. [accessed on 14 Sep,2019](Online)
- Webmd lamivudine[accessed on 24Aug2019] (Online)
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Lamivudine. [Updated 2019 May 1]. Available from:
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